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Masculinizing Hormone Therapy
Masculinizing hormone therapy, also known as transmasculine hormone therapy, is a form of hormone therapy and gender affirming therapy which is used to change the secondary sexual characteristics of transgender people from what is typically perceived as feminine to what is typically perceived as masculine. It is a common type of transgender hormone therapy (another being feminizing hormone therapy), and is predominantly used to treat transgender men, transmasculine individuals, and other gender diverse people who were assigned female at birth. Some intersex people also receive this form of therapy, either starting in childhood to confirm the assigned sex or later if the assignment proves to be incorrect. The purpose of this form of therapy is to cause the development of secondary sex characteristics such as voice deepening, increased body hair, enhanced size and sensitivity of the clitoris, redistributed fat, and muscle distribution. It cannot undo many of the changes produ ...
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Hormone Therapy
Hormone therapy or hormonal therapy is the use of hormones in medical treatment. Treatment with hormone antagonists may also be referred to as hormonal therapy or antihormone therapy. The most general classes of hormone therapy are hormonal therapy (oncology), oncologic hormone therapy, hormone replacement therapy (for menopause), androgen replacement therapy (ART), oral contraceptive pills, and Gender-affirming hormone therapy. __TOC__ Types * Hormone replacement therapy (HRT), also known as menopausal hormone therapy (MHT), is for women with menopause, menopausal symptoms. It is based on the idea that the treatment may prevent discomfort caused by diminished circulating estrogen and progesterone hormones, or in the case of the surgically or prematurely menopausal, that it may prolong life and may reduce incidence of dementia. It involves the use of one or more of a group of medications designed to artificially boost hormone levels. The main types of hormones involved are estrogen ...
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Puberty
Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a female, the testicles in a male. In response to the signals, the gonads produce hormones that stimulate libido and the growth, function, and transformation of the brain, bones, muscle, blood, skin, hair, breasts, and sex organs. Physical growth—height and weight—accelerates in the first half of puberty and is completed when an adult body has been developed. Before puberty, the external sex organs, known as primary sexual characteristics, are sex characteristics that distinguish males and females. Puberty leads to sexual dimorphism through the development of the secondary sex characteristics, which further distinguish the sexes. On average, females begin puberty at age 10½ and complete puberty at ages 15-17; males begin at ages 11½-12 and complete pube ...
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Sleep Apnea
Sleep apnea (sleep apnoea or sleep apnœa in British English) is a sleep-related breathing disorder in which repetitive Apnea, pauses in breathing, periods of shallow breathing, or collapse of the upper airway during sleep results in poor ventilation and sleep disruption. Each pause in breathing can last for a few seconds to a few minutes and often occurs many times a night. A choking or snorting sound may occur as breathing resumes. Common symptoms include daytime sleepiness, snoring, and non restorative sleep despite adequate sleep time. Because the disorder disrupts normal sleep, those affected may experience sleepiness or feel tired during the day. It is often a chronic condition. Sleep apnea may be categorized as obstructive sleep apnea (OSA), in which breathing is interrupted by a blockage of air flow, central sleep apnea (CSA), in which regular unconscious breath simply stops, or a combination of the two. OSA is the most common form. OSA has four key contributors; these ...
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Hypertension
Hypertension, also known as high blood pressure, is a Chronic condition, long-term Disease, medical condition in which the blood pressure in the artery, arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. Hypertension is a major cause of premature death worldwide. High blood pressure is classified as essential hypertension, primary (essential) hypertension or secondary hypertension. About 90–95% of cases are primary, defined as high blood pressure due to non-specific lifestyle and Genetics, genetic factors. Lifestyle factors that increase the risk include excess salt in the diet, overweight, excess body weight, smoking, physical inactivity and Alcohol (drug), alcohol use. The remaining 5–10% of cases are categorized as secondary hypertension, d ...
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Hormone-sensitive Cancer
A hormone-sensitive cancer, or hormone-dependent cancer, is a type of cancer that is dependent on a hormone for growth and/or survival. Examples include breast cancer, which is dependent on estrogens like estradiol, and prostate cancer, which is dependent on androgens like testosterone. Hormones can cause some tumors grow and spread, which are so-called hormone-sensitive or hormone-dependent cancer. If a tumor is hormone-sensitive, it means that there are special proteins called receptors on cells surface. When the hormone binds to a matched receptor, it results in the growth and spread of cancer cells. Mechanism of carcinogenesis While tumor initiating event for hormone-related cancers can be varied, the promotion event and subsequent proliferation is driven by a sex hormone. Both endogenous and exogenous hormones, by driving cell proliferation, increased the number of cell divisions and the opportunity for random genetic errors to lead to cancer. Hormone-sensitive cancer ...
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Pregnancy
Pregnancy is the time during which one or more offspring gestation, gestates inside a woman's uterus. A multiple birth, multiple pregnancy involves more than one offspring, such as with twins. Conception (biology), Conception usually occurs following sexual intercourse, vaginal intercourse, but can also occur through assisted reproductive technology procedures. A pregnancy may end in a Live birth (human), live birth, a miscarriage, an Abortion#Induced, induced abortion, or a stillbirth. Childbirth typically occurs around 40 weeks from the start of the Menstruation#Onset and frequency, last menstrual period (LMP), a span known as the Gestational age (obstetrics), ''gestational age''; this is just over nine months. Counting by Human fertilization#Fertilization age, ''fertilization age'', the length is about 38 weeks. Implantation (embryology), Implantation occurs on average 8–9 days after Human fertilization, fertilization. An ''embryo'' is the term for the deve ...
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Contraindication
In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a reason to use a certain treatment. Absolute contraindications are contraindications for which there are no reasonable circumstances for undertaking a course of action (that is, overriding the prohibition). For example: * Children and teenagers with viral infections should not be given aspirin because of the risk of Reye syndrome. * A person with an anaphylactic food allergy should never eat the food to which they are allergic. * A person with hemochromatosis should not be administered iron preparations. * Some medications are so teratogenic that they are absolutely contraindicated in pregnancy; examples include thalidomide and isotretinoin. Relative contraindications are contraindications for circumstances in which the patient is at hig ...
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Somatics
Somatics is a field within bodywork (alternative medicine), bodywork and movement studies which emphasizes proprioception, internal physical perception and experience. The term is used in movement therapy to signify approaches based on the soma, or "the body as perceived from within", including Skinner Releasing Technique, Alexander technique, the Feldenkrais method, Gerda Alexander, Eutony, Rolfing Structural Integration, among others. In dance, the term refers to techniques based on the dancer's internal sensation, in contrast with "performance, performative techniques", such as ballet or modern dance, which emphasize the external observation of movement by an audience. Somatic techniques may be used in bodywork, psychotherapy, dance, or spiritual practices. History An early precursor of the somatic movement in Western culture was the 19th-century physical culture movement. This movement sought to integrate movement practices, or "gymnastics", related to military and athletic ...
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Gender Identity
Gender identity is the personal sense of one's own gender. Gender identity can correlate with a person's assigned sex or can differ from it. In most individuals, the various biological determinants of sex are congruent and consistent with the individual's gender identity. Gender expression typically reflects a person's gender identity, but this is not always the case. While a person may express behaviors, attitudes, and appearances consistent with a particular gender role, such expression may not necessarily reflect their gender identity. The term ''gender identity'' was coined by psychiatry professor Robert J. Stoller in 1964 and popularized by psychologist John Money. In most societies, there is a basic division between gender attributes associated with males and females, a gender binary to which most people adhere and which includes expectations of masculinity and femininity in all aspects of sex and gender: biological sex, gender identity, gender expression, and sexual orient ...
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Passing (gender)
In the context of gender, passing is someone being perceived as a gender they identify as or are attempting to be seen as, rather than their sex assigned at birth. Historically, this was common among women who served in occupations where they were prohibited, such as in combat roles in the military. For transgender people, it is when a person is perceived as a cisgender person of their gender instead of the sex they were assigned at birth. For example, a transgender man is passing if he is perceived as a cisgender man. The appropriateness of the term ''passing'', and the desirability of blending into society, are debated within the transgender community. A trans person who is perceived as cisgender may face less prejudice, harassment, and risk of violence, as well as better employment opportunities. This is sometimes termed ''passing privilege''. Terminology Gender attribution Gender attribution is the process by which an observer decides which gender they believe another pe ...
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Gender Dysphoria
Gender dysphoria (GD) is the distress a person experiences due to inconsistency between their gender identitytheir personal sense of their own genderand their sex assigned at birth. The term replaced the previous diagnostic label of gender identity disorder (GID) in 2013 with the release of the diagnostic manual DSM-5. The condition was renamed to remove the stigma associated with the term ''disorder''. The International Classification of Diseases uses the term gender incongruence (GI) instead of ''gender dysphoria'', defined as a marked and persistent mismatch between gender identity and assigned gender, regardless of distress or impairment. Not all transgender people have gender dysphoria. Gender nonconformity is not the same thing as gender dysphoria and does not always lead to dysphoria or distress. In pre-pubertal youth, the diagnoses are gender dysphoria in childhood and gender incongruence of childhood. The causes of gender incongruence are unknown but a gender i ...
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GnRH Analogue
A GnRH modulator, or GnRH receptor modulator, also known as an LHRH modulator or LHRH receptor modulator, is a type of medication which modulates the GnRH receptor, the biological target of the hypothalamic hormone gonadotropin-releasing hormone (GnRH; also known as luteinizing-releasing hormone, or LHRH). They include GnRH agonists and GnRH antagonists. These medications may be GnRH analogues like leuprorelin and cetrorelix – peptides that are structurally related to GnRH – or small-molecules like elagolix and relugolix, which are structurally distinct from and unrelated to GnRH analogues. GnRH modulators affect the secretion of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn affects the gonads, influencing their function and hence fertility as well as the production of sex steroids, including that of estradiol and progesterone in women and of testosterone in men. As such, GnRH modulators can also be described a ...
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