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MDM1EA
''N''-Methyl-1-(3,4-methylenedioxyphenyl)-1-ethanamine (MDM1EA), also known as α,''N''-dimethyl-3,4-methylenedioxybenzylamine (α,''N''-DMMDBA) or as α,''N''-dimethylpiperonylamine, is an entactogen-like drug of the benzylamine family related to MDMA. It is the analogue of MDMA in which the side chain has been shortened by one carbon atom. The drug has been found to be a weak serotonin reuptake inhibitor and partially substituted for MDMA in rodent drug discrimination tests at the highest assessed doses. The effects of α,''N''-DMMDBA in humans are unknown. It is not a controlled substance in the United States as of 2011. Homo-MDMA (HMDMA), an analogue of MDMA in which the side chain was extended by one carbon atom, has also been synthesized and studied. It partially substituted for MDMA similarly to MDM1EA. See also * ALPHA * M-ALPHA * Benzylpiperazine Benzylpiperazine (BZP) is a substance often used as a recreational drug and is known to have euphoriant and stimu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzodioxoles
The substituted methylenedioxyphenethylamines (abbreviated as MDxx) represent a diverse chemical class of compounds derived from phenethylamines. This category encompasses numerous Psychoactive drug, psychoactive substances with Empathogen, entactogenic, Psychedelic drug, psychedelic, and/or stimulant properties, in addition to entheogens. These compounds find application as research chemicals, designer drugs, and recreational substances. The base chemical compound, compound of the MDxx class is methylenedioxyphenethylamine, 3,4-methylenedioxyphenethylamine (MDPEA), and the prototypical agent of this class is MDMA, 3,4-methylenedioxy-''N''-methylamphetamine (MDMA; "ecstasy"). Other notable MDxx class substances include 3,4-methylenedioxyamphetamine (MDA), methylenedioxyethylamphetamine, 3,4-methylenedioxy-''N''-ethylamphetamine (MDEA; "Eve"), methylbenzodioxolylbutanamine, ''N''-methyl-1,3-benzodioxolylbutanamine (MBDB; "Eden"), and methylenedioxymethcathinone, 3,4-methylenedioxy- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homo-MDMA
Homo-MDMA (HMDMA), also known as α,''N''-dimethyl-3-(3,4-methylenedioxyphenyl)propylamine, is an entactogen-like drug of the phenylpropylamine group related to MDMA. It is an analogue of MDMA in which the side chain has been lengthened by one carbon atom. It showed very weak induction of serotonin release (much less than that of MDMA or methamphetamine) and no significant release of dopamine in rat brain synaptosomes. As such, its monoamine-releasing activity was said to have been essentially abolished relative to MDMA. The drug partially substituted for MDMA in rodent drug discrimination tests but produced seizures at high doses. Based on unpublished findings by Alexander Shulgin, homo-MDMA has been said to be inactive in humans. However, it has been encountered as a designer and recreational drug in Japan and was being sold as " MBDB". It is not a controlled substance in the United States as of 2011. See also * Homo-MDA * MDM1EA * ALPHA Alpha (uppercase , lower ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzylamine
Benzylamine, also known as phenylmethylamine, is an Organic chemistry, organic chemical compound with the Structural formula#Condensed formulas, condensed structural formula C6H5CH2NH2 (sometimes abbreviated as Phenyl group#Nomenclature, PhCH2NH2 or Benzyl#Abbreviations, BnNH2). It consists of a benzyl group, C6H5CH2, attached to an amine functional group, NH2. This colorless water-soluble liquid is a common precursor in organic chemistry and used in the industrial production of many pharmaceuticals. The hydrochloride salt was used to treat motion sickness on the Mercury-Atlas 6 mission in which NASA astronaut John Glenn became the first American to orbit the Earth. Manufacturing Benzylamine can be produced by several methods, the main industrial route being the reaction of benzyl chloride and ammonia. It is also produced by the reduction of benzonitrile and reductive amination of benzaldehyde, both done over Raney nickel. : It was first produced accidentally by Rudolf Leucka ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzylamines
Benzylamine, also known as phenylmethylamine, is an organic chemical compound with the condensed structural formula C6H5CH2NH2 (sometimes abbreviated as PhCH2NH2 or BnNH2). It consists of a benzyl group, C6H5CH2, attached to an amine functional group, NH2. This colorless water-soluble liquid is a common precursor in organic chemistry and used in the industrial production of many pharmaceuticals. The hydrochloride salt was used to treat motion sickness on the Mercury-Atlas 6 mission in which NASA astronaut John Glenn became the first American to orbit the Earth. Manufacturing Benzylamine can be produced by several methods, the main industrial route being the reaction of benzyl chloride and ammonia. It is also produced by the reduction of benzonitrile and reductive amination of benzaldehyde, both done over Raney nickel. : It was first produced accidentally by Rudolf Leuckart in the reaction of benzaldehyde with formamide in a process now known as the Leuckart reaction. Bio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homo-MDA
Homo-MDA (HMDA), also known as α-methyl-γ-(3,4-methylenedioxyphenyl)propylamine, is a entactogen-like drug related to 3,4-methylenedioxyamphetamine (MDA). It is an analogue of MDA in which the side chain has been lengthened by one carbon atom. Unlike the stimulant amphetamine and the psychedelic DOM, and in contrast to MDA, homo-MDA has no effect on locomotor activity in rodents. It was found to be more toxic than MDA in rodents. The effects of homo-MDA in humans are unknown. It is not a controlled substance in the United States as of 2011. See also * Homo-MDMA * MDM1EA * ALPHA Alpha (uppercase , lowercase ) is the first letter of the Greek alphabet. In the system of Greek numerals, it has a value of one. Alpha is derived from the Phoenician letter ''aleph'' , whose name comes from the West Semitic word for ' ... * M-ALPHA References External links Homo-MDA - isomer design Amines Benzodioxoles {{Pharmacology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methylenedioxybenzylpiperazine
1-(3,4-Methylenedioxybenzyl)piperazine (MDBZP, piperonylpiperazine) is a chemical compound of the piperazine chemical class related to benzylpiperazine (BZP). MDBZP has been sold as a designer drug and has even been found as an ingredient in street Ecstasy pills. See also * 3,4-Methylenedioxy-''N''-methylamphetamine (MDMA) * Substituted piperazine * MDM1EA ''N''-Methyl-1-(3,4-methylenedioxyphenyl)-1-ethanamine (MDM1EA), also known as α,''N''-dimethyl-3,4-methylenedioxybenzylamine (α,''N''-DMMDBA) or as α,''N''-dimethylpiperonylamine, is an entactogen-like drug of the benzylamine family related t ... References External links * Benzodioxoles Benzylpiperazines Designer drugs 1-Piperazinyl compounds {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M-ALPHA
M-ALPHA, also known as 3,4-methylenedioxy-α-ethyl-''N''-methylbenzylamine or as α-ethyl-''N''-methylpiperonylamine, is a psychoactive drug of the substituted benzylamine group. It was reported by Alexander Shulgin in his book PIHKAL as a positional isomer of MDMA. Subsequently, the drug was encountered as a designer drug in the United Kingdom in 2010 and was reported to the EMCDDA new drug monitoring service. It was described by Shulgin as similar in action to its demethylated homologue, ALPHA, but with roughly twice the duration and twice the potency. ALPHA itself was described as active at doses of 10 to 140mg, with a duration of about 3hours, and producing eyes-closed "dreams", some body tingling, and a pleasant positive feeling, but without any appetite suppression. M-ALPHA was encountered as a designer drug by 2010. See also * ALPHA Alpha (uppercase , lowercase ) is the first letter of the Greek alphabet. In the system of Greek numerals, it has a value of on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ALPHA (drug)
ALPHA, also known as 3,4-methylenedioxy-α-ethylbenzylamine, is a psychoactive drug of the substituted benzylamine group and a positional isomer of 3,4-methylenedioxyamphetamine (MDA). It is also a benzylamine analogue of 3,4-methylenedioxyamphetamine (MDA). ALPHA was first synthesized by Alexander Shulgin. In his book ''PIHKAL'' on the MDA page, the threshold dosage is listed as 10mg. At mild threshold dosages (around 10mg) there are eyes-closed "dreams" with some body tingling, at higher doses (up to 140mg) was reported to produce a pleasant, positive feeling. This compound is not anoretic at any dose. Its duration is about 3hours. Very little data exists about the pharmacological properties, metabolism, and toxicity of ALPHA. The drug was encountered as a novel designer drug by 1996. See also * M-ALPHA (''N''-methyl analogue) * MDM1EA (3,4-methylenedioxy-α,''N''-dimethylbenzylamine) * Methylenedioxybenzylpiperazine (MDBZP) * Homo-MDA * Homo-MDMA Homo-MDMA (HMDMA), a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Entactogen
Entactogens, also known as empathogens or connectogens, are a class of psychoactive drugs that induce the production of experiences of emotional communion, oneness, connectedness, emotional openness—that is, empathy—as particularly observed and reported for experiences with MDMA. This class of drug is distinguished from the classes of hallucinogens or psychedelics and stimulants, although entactogens, for instance MDMA, can also have these properties. Entactogens are used both as recreational drugs and are being investigated for medical use in the treatment of psychiatric disorders, for instance MDMA-assisted therapy for post-traumatic stress disorder (PTSD). Notable members of this class include MDMA, MDA, MDEA, MDOH, MBDB, 5-APB, 5-MAPB, 6-APB, 6-MAPB, methylone, mephedrone, αMT, αET, and MDAI, among others. Most entactogens are phenethylamines and amphetamines, although several, such as αMT and αET, are tryptamines. When referring to MDMA and its cou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzylpiperazine
Benzylpiperazine (BZP) is a substance often used as a recreational drug and is known to have euphoriant and stimulant properties. Several studies conducted between 2000 and 2011 found that the effects of BZP are similar to amphetamine, although BZP's dosage is roughly 10 times higher by weight. Adverse effects have been reported following its use including psychosis, acute psychosis, renal toxicity and seizures. Deaths from piperazine derivatives are extremely rare, but there has been at least one death apparently due to BZP alone. Its sale is banned in several countries, including Australia, Canada, New Zealand, the United States, the Republic of Ireland, the United Kingdom, Bulgaria, Romania and other parts of Europe. History Development history BZP was first synthesized by Burroughs Wellcome & Company in 1944. It is often claimed that it was originally synthesized as a potential antihelminthic (anti-parasitic) agent for use in farm animals, but its synthesis is thought ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Synthesis
Chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products. This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds (known as '' reagents'' or ''reactants'') that will experience a transformation under certain conditions. Various reaction types can be applied to formulate a desired product. This requires mixing the compounds in a reaction vessel, such as a chemical reactor or a simple round-bottom flask. Many reactions require some form of processing (" work-up") or purification procedure to isolate the final product. The amount produced by chemical synthesis is known as the '' reaction yield''. Typically, yields are expressed as a mass in grams (in a laboratory setting) or as a percentage of the total theoretical quantity that could be produced based ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Controlled Substance
A controlled substance is generally a drug or chemical whose manufacture, possession and use is regulated by a government, such as illicitly used drugs or prescription medications that are designated by law. Some treaties, notably the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, provide internationally agreed-upon "schedules" of controlled substances, which have been incorporated into national laws; however, national laws usually significantly expand on these international conventions. Some precursor chemicals used for the production of illegal drugs are also controlled substances in many countries, even though they may lack the pharmacological effects of the drugs themselves. Substances are classified according to schedules and consist primarily of potentially psychoactive substances and anabolic steroids. The controlled substanc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
