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MCL Restaurant
MCL may refer to: Medicine * Mantle cell lymphoma * Mast cell leukemia * Medial collateral ligament * Medical Center Leeuwarden * Microlitre (μL), or microliter * Midclavicular line * Mucocutaneous leishmaniasis * Multiple cutaneous leiomyoma * Myeloid cell leukemia sequence 1 (MCL1) Companies and organizations * MCL Cafeterias, a chain of American cafeteria-style restaurants * Mahanadi Coalfields Limited, a coal-producing company in India * Marine Corps League * Movement for Christian Liberation * Malabar Cements Limited a cement company in Kerala * McLaren, a British racing team and McLaren Automotive, automaker * Mysore Cements Limited a cement company Law * Michigan Compiled Laws Science, engineering and industry * Maximum Contaminant Level * Coupling loss, Maximum Coupling Loss * Mid-Canada Line of early-warning radar stations Computer Science and mathematics * 1150 in Roman numerals * Macintosh Common Lisp * McLaughlin group (mathematics), a sporadic simple gr ...
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Mantle Cell Lymphoma
Mantle cell lymphoma (MCL) is a type of Non-Hodgkin lymphoma, non-Hodgkin's lymphoma, comprising about 6% of cases. It is named for the mantle zone of the lymph nodes where it develops. The term 'mantle cell lymphoma' was first adopted by Raffeld and Jaffe in 1991. MCL is a subtype of B-cell lymphoma, due to CD5 (protein), CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles. MCL cells generally over-express cyclin D1 due to the t(11:14) translocation, a chromosomal translocation in the DNA. Signs and symptoms People with mantle cell lymphoma typically present with symptoms later in life, with a median age of onset between 60 and 70 years of age. In Western countries MCL accounts for around 7% of adult non-Hodgkin's lymphomas, with between 4 and 8 per cases per million diagnosed each year. The incidence of MCL increases with age. In the United States, the median age for its diagnosis is 68 years. Three-q ...
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