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MADD (other)
MADD or Madd may refer to: * Mothers Against Drunk Driving, a nonprofit organization in the United States and Canada that seeks to stop driving with any amount of alcohol in the bloodstream * Myoadenylate deaminase deficiency or Adenosine monophosphate deaminase deficiency type 1, a metabolic disorder * Multiple acyl-CoA dehydrogenase deficiency, another name for the genetic disorder Glutaric acidemia type 2 * MADD (gene) or MAP kinase-activating death domain protein * Madd, the fruit of ''Saba senegalensis'' * Maladaptive daydreaming, Maladaptive Daydreaming Disorder (written MaDD) * Mixed anxiety–depressive disorder, a psychological disorder {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mothers Against Drunk Driving
Mothers Against Drunk Driving (MADD) is a non-profit organization in the United States, Canada ( MADD Canada) and Brazil that seeks to stop driving with any amount of alcohol in the bloodstream, support those affected by drunk driving, prevent underage drinking, and strive for stricter impaired driving policy, whether that impairment is caused by alcohol or any other drug. The Irving, Texas-based organization was founded on September 5, 1980, in California by Candace Lightner after her 13-year-old daughter, Cari, was killed by a drunk driver. There is at least one MADD office in every state of the United States and at least one in each province of Canada. These offices offer victim services and many resources involving alcohol safety. MADD has claimed that drunk driving has been reduced by half since its founding. Positions According to MADD's website, "The mission of Mothers Against Drunk Driving is to end drunk driving, help fight drugged driving, support the victims of these vi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenosine Monophosphate Deaminase Deficiency Type 1
Adenosine monophosphate deaminase deficiency type 1 or AMPD1, is a human metabolic disorder in which the body consistently lacks the enzyme AMP deaminase, in sufficient quantities. This may result in exercise intolerance, muscle pain and muscle cramping. The disease was formerly known as myoadenylate deaminase deficiency (MADD). In virtually all cases, the deficiency has been caused by an SNP mutation, known as ''rs17602729'' or ''C34T''. While it was initially regarded as a recessive (or purely homozygous) disorder, some researchers have reported the existence of similarly deleterious effects from the heterozygous form of the SNP. In the homozygous form of the mutation, a single genetic base (character) has been changed from cytosine ("C") to thymine ("T") on both strands of Chromosome 1 – in other words, "C;C" has been replaced by "T;T". A rarer but analogous condition, in which two guanine bases ("G;G") bases (in the unmutated form) have been changed to adenine ("A;A") has al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multiple Acyl-CoA Dehydrogenase Deficiency
Glutaric acidemia type 2 is an autosomal recessive metabolic disorder that is characterised by defects in the ability of the body to use proteins and fats for energy. Incompletely processed proteins and fats can build up, leading to a dangerous chemical imbalance called acidosis. It is a metabolic myopathy, categorized under fatty acid metabolism disorder as that is the bioenergetic system that it affects the most. It also affects choline metabolism. The phenotypic presentation has 3 forms: a neonatal-onset form with congenital anomalies (type I), a neonatal-onset form without congenital anomalies (type II), and a late-onset form (type III). Individuals with glutaric acidemia type 2 frequently experience exercise-induced muscle fatigue, hypotonia, myalgia, and proximal muscle weakness. The symptoms not only overlap with another type of metabolic myopathy, that of mitochondrial myopathy, but MADD also impairs the FAD-dependent respiratory chain in the mitochondria of muscle cells ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MADD (gene)
MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the ''MADD'' gene. ''MADD'' is one out of four of the splice variants of the human ''IG20 ''(insulinoma-glucagonoma clone 20) gene which is located on human chromosome 11. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis Apoptosis (from ) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. Biochemistry, Biochemical events lead to characteristic cell changes (Morphology (biol .... The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expres ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saba Senegalensis
''Saba senegalensis'', known as ''weda'' in the Moore, French, and English languages and ‘’madd’’ in Wolof and ‘’laare’’ in Pulaar, is a fruit-producing plant of the Apocynaceae family, native to the Sahel region of sub-Saharan Africa. It has several common names in various West African languages. The tree grows predominantly on riverbanks and in woodlands in Senegal, Mali, Guinea-Bissau, The Gambia, Burkina Faso, Somalia and Ivory Coast. It has been observed growing as vine up trees, as a small erect shrub, and oftentimes growing to the size of a large tree. ICRISAT has cited ''S. senegalensis'' as a useful food crop plant and as a tool to combat soil degradation in rural Africa. Fruit The fruit of ''Saba senegalensis'' has a hard yellow peel containing large seeds embedded in a yellowish pulp, having a pleasing acidity similar to that of the tamarind. The flavor has also been compared to that of a mango. Drink Natives of the Sahel region often use the fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maladaptive Daydreaming
Maladaptive daydreaming, also called excessive daydreaming, is when an individual experiences excessive daydreaming that interferes with daily life. It is a proposed diagnosis of a disordered form of dissociative absorption, associated with excessive fantasy that is not recognized by any major medical or psychological criteria. Maladaptive daydreaming can result in distress, can replace human interaction and may interfere with normal functioning such as social life or work. Maladaptive daydreaming is not a widely recognized diagnosis and is not found in any major diagnostic manual of psychiatry or medicine. The term was coined in 2002 by Eli Somer of the University of Haifa. Somer's definition of the proposed condition is "extensive fantasy activity that replaces human interaction and/or interferes with academic, interpersonal, or vocational functioning." There has been limited research outside of Somer's. Range of daydreaming Daydreaming, a form of normal dissociation ass ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
