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Latrodectus Variolus
''Latrodectus variolus'', the northern black widow spider or northern widow, is a venomous species of spider in the genus '' Latrodectus'' of the family Theridiidae. The population is closely related to the southern black widow, '' Latrodectus mactans'', and the western black widow, ''Latrodectus hesperus'', of the genus. In North America, the species is commonly found in Middle Atlantic states (New Jersey, Delaware, Connecticut, Maryland). During the April–May mating season, it can travel north along the coast as far as Massachusetts in summer, and rarely, in southern Ontario and southern Quebec Quebec is Canada's List of Canadian provinces and territories by area, largest province by area. Located in Central Canada, the province shares borders with the provinces of Ontario to the west, Newfoundland and Labrador to the northeast, ..., Michigan, and at least as far northwest as parts of Wisconsin. A bite may cause latrodectism, and requires medical attention in the ...
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Charles Athanase Walckenaer
Baron Charles Athanase Walckenaer (25 December 1771 – 28 April 1852) was a French civil servant, writer, man of letters, and scientist. He was a polymath and wrote extensively on geography, natural history, and literature. Major contributions included his multi-volume natural histories of arachnids and insects, some published in collaboration with others. He was made a baron in 1823. Biography Walckenaer was born in Paris and after losing his parents at an early age he was raised by his uncle Charles-Nicolas Duclos Dufresnoy, a notary in the court of Louis XVI. His uncle's elite and educated circle made an impression on the young boy and he was sent to study at the universities of Oxford and Glasgow. Dufresnoy was guillotined in 1794 following the French Revolution for being associated with the regime. In 1793, Walckenaer was appointed head of the military transports in the Pyrenees, after which he pursued technical studies at the École Nationale des Ponts et Chaussées an ...
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Massachusetts
Massachusetts ( ; ), officially the Commonwealth of Massachusetts, is a U.S. state, state in the New England region of the Northeastern United States. It borders the Atlantic Ocean and the Gulf of Maine to its east, Connecticut and Rhode Island to its south, New Hampshire and Vermont to its north, and New York (state), New York to its west. Massachusetts is the List of U.S. states and territories by area, sixth-smallest state by land area. With a 2024 U.S. Census Bureau-estimated population of 7,136,171, its highest estimated count ever, Massachusetts is the most populous state in New England, the List of U.S. states and territories by population, 16th-most-populous in the United States, and the List of states and territories of the United States by population density, third-most densely populated U.S. state, after New Jersey and Rhode Island. Massachusetts was a site of early British colonization of the Americas, English colonization. The Plymouth Colony was founded in 16 ...
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Antivenom
Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection. Side effects may be severe. They include serum sickness, shortness of breath, and allergic reactions including anaphylaxis. Antivenom is traditionally made by collecting venom from the relevant animal and injecting small amounts of it into a domestic animal. The antibodies that form are then collected from the domestic animal's blood and purified. Versions are available for spider bites, snake bites, fish stings, and scorpion stings. Due to the high cost of producing antibody-based antivenoms and their short shelf lives when not refrigerated, alternative methods of production of antiven ...
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Toxicon
''Toxicon'' is a peer-reviewed scientific journal of toxinology and the official journal of the International Society on Toxinology and the North American Society of Toxinology. It is published by Elsevier and the editor-in-chief is Ray Norton. It aims to publish original research, novel findings, and review papers on toxins and their chemical, toxicological, pharmacological, and immunological properties. The journal was established in 1962. According to the ''Journal Citation Reports'', ''Toxicon'' has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 3.033. References External links * Academic journals established in 1962 Elsevier academic journals English-language journals Toxicology journals Pharmacology journals {{pharmacology-jou ...
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LD-50
In toxicology, the median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given substance. The value of LD50 for a substance is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity. A lower LD50 is indicative of higher toxicity. The term LD50 is generally attributed to John William Trevan. The test was created by J. W. Trevan in 1927. The term semilethal dose is occasionally used in the same sense, in particular with translations of foreign language text, but can also refer to a sublethal dose. LD50 is usually determined by tests on animals such as laboratory mice. In 2011, the U.S. Food and Drug Administration approved alternative methods to LD50 for testing the cosmetic drug botox without animal tests. Conventions The LD50 is usually express ...
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Latrodectism
Latrodectism () is the illness caused by the bite of ''Latrodectus'' spiders (the black widow spider and related species). Pain, muscle rigidity, vomiting, and sweating are the symptoms of latrodectism. There are several spider species all named black widow: southern black widow spider (''L. mactans''), the European black widow (''L. tredecimguttatus''), Western black widow spider (''L. hesperus''), Northern black widow spider (''L. variolus''). Other ''Latrodectus'' that cause latrodectism are the Australian redback spider (''L. hasselti''), the New Zealand katipō spider (''L. katipo'') and the South American '' Latrodectus corallinus'' and ''Latrodectus curacaviensis''. Several other members of the genus ''Latrodectus'' are not commonly associated with latrodectism, including the cosmopolitan brown widow (''L. geometricus''). Signs and symptoms Symptoms of a bite depend on the amount of venom injected. A bite of ''Latrodectus'' may not ...
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Quebec
Quebec is Canada's List of Canadian provinces and territories by area, largest province by area. Located in Central Canada, the province shares borders with the provinces of Ontario to the west, Newfoundland and Labrador to the northeast, New Brunswick to the southeast and a coastal border with the territory of Nunavut. In the south, it shares a border with the United States. Between 1534 and 1763, what is now Quebec was the List of French possessions and colonies, French colony of ''Canada (New France), Canada'' and was the most developed colony in New France. Following the Seven Years' War, ''Canada'' became a Territorial evolution of the British Empire#List of territories that were once a part of the British Empire, British colony, first as the Province of Quebec (1763–1791), Province of Quebec (1763–1791), then Lower Canada (1791–1841), and lastly part of the Province of Canada (1841–1867) as a result of the Lower Canada Rebellion. It was Canadian Confederation, ...
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Ontario
Ontario is the southernmost Provinces and territories of Canada, province of Canada. Located in Central Canada, Ontario is the Population of Canada by province and territory, country's most populous province. As of the 2021 Canadian census, it is home to 38.5% of the country's population, and is the second-largest province by total area (after Quebec). Ontario is Canada's fourth-largest jurisdiction in total area of all the Canadian provinces and territories. It is home to the nation's capital, Ottawa, and its list of the largest municipalities in Canada by population, most populous city, Toronto, which is Ontario's provincial capital. Ontario is bordered by the province of Manitoba to the west, Hudson Bay and James Bay to the north, and Quebec to the east and northeast. To the south, it is bordered by the U.S. states of (from west to east) Minnesota, Michigan, Ohio, Pennsylvania, and New York (state), New York. Almost all of Ontario's border with the United States follows riv ...
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Maryland
Maryland ( ) is a U.S. state, state in the Mid-Atlantic (United States), Mid-Atlantic region of the United States. It borders the states of Virginia to its south, West Virginia to its west, Pennsylvania to its north, and Delaware to its east, as well as with the Atlantic Ocean to its east, and the national capital and federal district of Washington, D.C. to the southwest. With a total area of , Maryland is the List of U.S. states and territories by area, ninth-smallest state by land area, and its population of 6,177,224 ranks it the List of U.S. states and territories by population, 18th-most populous state and the List of states and territories of the United States by population density, fifth-most densely populated. Maryland's capital city is Annapolis, Maryland, Annapolis, and the state's most populous city is Baltimore. Maryland's coastline was first explored by Europeans in the 16th century. Prior to that, it was inhabited by several Native Americans in the United States ...
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Black Widow Spider
''Latrodectus'' is a broadly distributed genus of spiders with several species that are commonly known as the true widows. This group is composed of those often loosely called black widow spiders, brown widow spiders, and similar spiders. However, the diversity of species is much greater. A member of the family Theridiidae, this genus contains 34 species, which include several North American "black widows" (southern Black Widow ''Latrodectus mactans'', western black widow ''Latrodectus hesperus'', and northern black widow ''Latrodectus variolus''). Besides these, North America also has the red widow ''Latrodectus bishopi'' and the brown widow ''Latrodectus geometricus'', which, in addition to North America, has a much wider geographic distribution. Elsewhere, others include the European black widow (''Latrodectus tredecimguttatus''), the Australian redback spider (''Latrodectus hasseltii'') and the closely related New Zealand katipō (''Latrodectus katipo''), several different spe ...
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Connecticut
Connecticut ( ) is a U.S. state, state in the New England region of the Northeastern United States. It borders Rhode Island to the east, Massachusetts to the north, New York (state), New York to the west, and Long Island Sound to the south. Its capital is Hartford, Connecticut, Hartford, and its most populous city is Bridgeport, Connecticut, Bridgeport. Connecticut lies between the major hubs of New York City and Boston along the Northeast megalopolis, Northeast Corridor, where the New York metropolitan area, New York-Newark Combined Statistical Area, which includes four of Connecticut's seven largest cities, extends into the southwestern part of the state. Connecticut is the List of U.S. states and territories by area, third-smallest state by area after Rhode Island and Delaware, and the List of U.S. states and territories by population, 29th most populous with more than 3.6 million residents as of 2024, ranking it fourth among the List of states and territories of the Unite ...
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Delaware
Delaware ( ) is a U.S. state, state in the Mid-Atlantic (United States), Mid-Atlantic and South Atlantic states, South Atlantic regions of the United States. It borders Maryland to its south and west, Pennsylvania to its north, New Jersey to its northeast, and the Atlantic Ocean to its east. The state's name derives from the adjacent Delaware Bay, which in turn was named after Thomas West, 3rd Baron De La Warr, an English nobleman and the Colony of Virginia's first colonial-era governor. Delaware occupies the northeastern portion of the Delmarva Peninsula, and some islands and territory within the Delaware River. It is the List of U.S. states and territories by area, second-smallest and List of U.S. states and territories by population, sixth-least populous state, but also the List of U.S. states and territories by population density, sixth-most densely populated. Delaware's List of municipalities in Delaware, most populous city is Wilmington, Delaware, Wilmington, and the ...
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