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Laryngeal Perichondritis
Perichondritis is inflammation of the perichondrium, a layer of connective tissue which surrounds cartilage. A common form, auricular perichondritis (''perichondritis auriculae'') involves infection of the pinna due to infection of traumatic or surgical wound or the spread of inflammation into depth (e.g. Infected transcartilaginous ear piercings). It may lead to severe deformation of the pinna if not treated vigorously with IV antibiotics. The causative organism is usually ''Pseudomonas aeruginosa''. A rare form is laryngeal perichondritis (''perichondritis laryngis''). It develops suddenly due to an injury, virulent organisms or compromised immune status of the host, and also affects cartilage of the larynx. This may result in deformations and stenoses. Signs and symptoms Signs of perichondritis or chondritis in patients with an embedded earring are similar (these include pain, swelling and erythema of the overlying skin) and fluctuant swelling indicate an abscess th ...
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Pinna (anatomy)
The auricle or auricula is the visible part of the ear that is outside the head. It is also called the pinna (Latin for 'wing' or ' fin', : pinnae), a term that is used more in zoology. Structure The diagram shows the shape and location of most of these components: * '' antihelix'' forms a 'Y' shape where the upper parts are: ** ''Superior crus'' (to the left of the ''fossa triangularis'' in the diagram) ** ''Inferior crus'' (to the right of the ''fossa triangularis'' in the diagram) * ''Antitragus'' is below the ''tragus'' * ''Aperture'' is the entrance to the ear canal * ''Auricular sulcus'' is the depression behind the ear next to the head * ''Concha'' is the hollow next to the ear canal * Conchal angle is the angle that the back of the ''concha'' makes with the side of the head * ''Crus'' of the helix is just above the ''tragus'' * ''Cymba conchae'' is the narrowest end of the ''concha'' * External auditory meatus is the ear canal * ''Fossa triangularis'' is the depression ...
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Otorhinolaryngology
Otorhinolaryngology ( , abbreviated ORL and also known as otolaryngology, otolaryngology–head and neck surgery (ORL–H&N or OHNS), or ear, nose, and throat (ENT)) is a surgical subspecialty within medicine that deals with the surgical and medical management of conditions of the head and neck. Doctors who specialize in this area are called otorhinolaryngologists, otolaryngologists, head and neck surgeons, or ENT surgeons or physicians. Patients seek treatment from an otorhinolaryngologist for diseases of the ear, Human nose, nose, throat, base of skull, base of the skull, head, and neck. These commonly include functional diseases that affect the senses and activities of eating, drinking, speaking, breathing, swallowing, and hearing. In addition, ENT surgery encompasses the surgical management of cancers and benign tumors and reconstruction of the head and neck as well as plastic surgery of the face, scalp, and neck. Etymology The term is a combination of Neo-Latin classic ...
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Otitis Externa
Otitis externa, also called swimmer's ear, is inflammation of the ear canal. It often presents with ear pain, swelling of the ear canal, and occasionally decreased hearing. Typically there is pain with movement of the outer ear. A high fever is typically not present except in severe cases. Otitis externa may be acute (lasting less than six weeks) or chronic (lasting more than three months). Acute cases are typically due to bacterial infection, and chronic cases are often due to allergies and autoimmune disorders. The most common cause of otitis externa is bacterial. Risk factors for acute cases include swimming, minor trauma from cleaning, using hearing aids and ear plugs, and other skin problems, such as psoriasis and dermatitis. People with diabetes are at risk of a severe form of ''malignant otitis externa''. Diagnosis is based on the signs and symptoms. Culturing the ear canal may be useful in chronic or severe cases. Acetic acid ear drops may be used as a preventive m ...
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Perichondrium
The perichondrium (from Greek and ) is a layer of dense irregular connective tissue that surrounds the cartilage of developing bone. It consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibres. The chondrogenic layer remains undifferentiated and can form chondroblasts. Perichondrium can be found around the perimeter of elastic cartilage and hyaline cartilage. Perichondrium is a type of irregular collagenous ordinary connective tissue, and also functions in the growth and repair of cartilage. Perichondrium contains type I collagen Type I collagen is the most abundant collagen of the human body, consisting of around 90% of the body's total collagen in vertebrates. Due to this, it is also the most abundant protein type found in all vertebrates. Type I forms large, eosinop ... and type XII collagen. References External links * Iowa Histology Index 4/iv-05' - "Slide 12, ...
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Connective Tissue
Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. It develops mostly from the mesenchyme, derived from the mesoderm, the middle embryonic germ layer. Connective tissue is found in between other tissues everywhere in the body, including the nervous system. The three meninges, membranes that envelop the brain and spinal cord, are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells. Blood and lymph are classed as specialized fluid connective tissues that do not contain fiber. All are immersed in the body water. The cells of connective tissue include fibroblasts, adipocytes, macrophages, mast cells and leukocytes. The term "connective tissue" (in German, ) was introduced in 1830 by Johannes Peter Müller. The tissue was already recognized as ...
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Cartilage
Cartilage is a resilient and smooth type of connective tissue. Semi-transparent and non-porous, it is usually covered by a tough and fibrous membrane called perichondrium. In tetrapods, it covers and protects the ends of long bones at the joints as articular cartilage, and is a structural component of many body parts including the rib cage, the neck and the bronchial tubes, and the intervertebral discs. In other taxa, such as chondrichthyans and cyclostomes, it constitutes a much greater proportion of the skeleton. It is not as hard and rigid as bone, but it is much stiffer and much less flexible than muscle. The matrix of cartilage is made up of glycosaminoglycans, proteoglycans, collagen fibers and, sometimes, elastin. It usually grows quicker than bone. Because of its rigidity, cartilage often serves the purpose of holding tubes open in the body. Examples include the rings of the trachea, such as the cricoid cartilage and carina. Cartilage is composed of specialized c ...
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Pseudomonas Aeruginosa
''Pseudomonas aeruginosa'' is a common Bacterial capsule, encapsulated, Gram-negative bacteria, Gram-negative, Aerobic organism, aerobic–facultative anaerobe, facultatively anaerobic, Bacillus (shape), rod-shaped bacteria, bacterium that can cause disease in plants and animals, including humans. A species of considerable medical importance, ''P. aeruginosa'' is a multiple drug resistance, multidrug resistant pathogen recognized for its ubiquity, its Intrinsic and extrinsic properties, intrinsically advanced antibiotic resistance mechanisms, and its association with serious illnesses – hospital-acquired infections such as ventilator-associated pneumonia and various sepsis syndromes. ''P. aeruginosa'' is able to selectively inhibit various antibiotics from penetrating its outer membrane'' ''– and has high resistance to several antibiotics. According to the World Health Organization ''P. aeruginosa'' poses one of the greatest threats to humans in terms of an ...
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Immune Status
In immunology, immunocompetence is the ability of the body to produce a normal immune response following exposure to an antigen. Immunocompetence is the opposite of immunodeficiency (also known as ''immuno-incompetence'' or being ''immuno-compromised''). In reference to lymphocytes, immunocompetence means that a B cell or T cell is mature and can recognize antigens and allow a person to mount an immune response. In order for lymphocytes such as T cells to become immunocompetent, which refers to the ability of lymphocyte cell receptors to recognize MHC molecules, they must undergo positive selection. Adaptive immunocompetence is regulated by growth hormone (GH), prolactin (PRL), and vasopressin (VP) – hormones secreted by the pituitary gland.Berczi, I., Quintanar-Stephano, A., & Kovacs, K. (2009). Neuroimmune regulation in immunocompetence, acute illness, and healing. Annals of the New York Academy of Sciences, 1153(1), 220–239. https://doi.org/10.1111/j.1749-6632.2008.03975 ...
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Larynx
The larynx (), commonly called the voice box, is an organ (anatomy), organ in the top of the neck involved in breathing, producing sound and protecting the trachea against food aspiration. The opening of larynx into pharynx known as the laryngeal inlet is about 4–5 centimeters in diameter. The larynx houses the vocal cords, and manipulates pitch (music), pitch and sound pressure, volume, which is essential for phonation. It is situated just below where the tract of the pharynx splits into the trachea and the esophagus. The word 'larynx' (: larynges) comes from the Ancient Greek word ''lárunx'' ʻlarynx, gullet, throatʼ. Structure The triangle-shaped larynx consists largely of cartilages that are attached to one another, and to surrounding structures, by muscles or by fibrous and elastic tissue components. The larynx is lined by a respiratory epithelium, ciliated columnar epithelium except for the vocal folds. The laryngeal cavity, cavity of the larynx extends from its tria ...
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Chondritis
Chondritis is inflammation of cartilage. It takes several forms, osteochondritis, costochondritis Costochondritis, also known as chest wall pain syndrome or costosternal syndrome, is a benign inflammation of the upper Costochondral joint, costochondral (rib to cartilage) and costosternal joint, sternocostal (cartilage to sternum) joints. 90% ..., and relapsing polychondritis among them. Costochondritis is notable for feeling like a heart attack. See also * Chondropathy * Chondrolysis * Perichondritis, commonly involving the outer ear * Relapsing polychondritis References Rheumatology {{musculoskeletal-disease-stub ...
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