Lactobacillus Salivarius
''Ligilactobacillus salivarius'' is a probiotic bacteria species that has been found to live in the gastrointestinal tract and exert a range of therapeutic properties including suppression of pathogenic bacteria. Therapeutic research Irritable bowel syndrome ''Ligilactobacillus salivarius'' has been found to be of benefit in the alleviation of flatulence in individuals suffering from irritable bowel syndrome. Pancreatic necrosis Pancreatic necrosis, if left untreated, has an almost 100 percent fatality rate due to bacterial translocation. ''Ligilactobacillus salivarius'' has been found to have a wide spectrum of coverage against pathogenic organisms that translocate from the gastrointestinal tract thereby demonstrating therapeutic benefit in the management of pancreatic necrosis. Research has shown that the addition of this species along with other probiotic species (specifically ''Bifidobacterium bifidum'', '' Bifidobacterium infantis'', ''Lactobacillus acidophilus'', ''L ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, Hot spring, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the nitrogen fixation, fixation of nitrogen from the Earth's atmosphere, atmosphere. The nutrient cycle includes the decomposition of cadaver, dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, suc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bacterial Translocation
Intestinal permeability is a term describing the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall, into the rest of the body. The intestine normally exhibits some permeability, which allows nutrients to pass through the gut, while also maintaining a barrier function to keep potentially harmful substances (such as antigens) from leaving the intestine and migrating to the body more widely. In a healthy human intestine, small particles (< 4 Å in radius) can migrate through tight junction claudin pore pathways, and particles up to 10–15 Å (3.5 kDa) can transit through the paracellular space uptake route. There is some evidence abnormally increased intestinal permeability may play a role in some chronic diseases and inflammatory conditions. The most well understood condition with observed increased intestinal permeability is celiac disease. Physiology The barrier formed by the intestinal epithelium separates the external ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Streptococcus Mutans
''Streptococcus mutans'' is a Facultative anaerobic organism, facultatively anaerobic, gram-positive coccus (round bacteria, bacterium) commonly found in the human oral cavity and is a significant contributor to dental caries, tooth decay. The microbe was first described by James Kilian Clarke in 1924. This bacterium, along with the closely related species ''Streptococcus sobrinus'', can cohabit the mouth: Both contribute to oral disease, and the expense of differentiating them in laboratory testing is often not clinically necessary. Therefore, for clinical purposes they are often considered together as a group, called the mutans streptococci. This grouping of similar bacteria with similar tropism can also be seen in the viridans streptococci – of which ''Streptococcus mutans'' is itself also a member. Ecology ''S. mutans'' is naturally present in the human oral microbiota, along with at least 25 other species of oral streptococci. The Taxonomy (biology), taxonomy of these ba ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tooth Decay
Tooth decay, also known as caries,The word 'caries' is a mass noun, and is not a plural of 'carie'.'' is the breakdown of teeth due to acids produced by bacteria. The resulting cavities may be a number of different colors, from yellow to black. Symptoms may include pain and difficulty eating. Complications may include periodontal disease, inflammation of the tissue around the tooth, tooth loss and infection or dental abscess, abscess formation. Tooth regeneration is an ongoing Stem-cell therapy, stem cell–based field of study that aims to find methods to reverse the effects of decay; current methods are based on easing symptoms. The cause of cavities is acid from bacteria dissolving the hard tissues of the teeth (Tooth enamel, enamel, dentin and cementum). The acid is produced by the bacteria when they break down food debris or sugar on the tooth surface. Simple sugars in food are these bacteria's primary energy source and thus a diet high in simple sugar is a risk factor. I ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Atopic Dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. Atopic dermatitis results in puritis, itchy, red, swollen, and cracked skin. Clear fluid may come from the affected areas, which can thicken over time. Atopic dermatitis affects about 20% of people at some point in their lives. It is more common in younger children. Females are affected slightly more often than males. Many people outgrow the condition. While the condition may occur at any age, it typically starts in childhood, with changing severity over the years. In children under one year of age, the face and limbs and much of the body may be affected. As children get older, the areas on the insides of the knees and folds of the elbows and around the neck are most commonly affected. In adults, the hands and feet are commonly affec ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Small Intestine
The small intestine or small bowel is an organ (anatomy), organ in the human gastrointestinal tract, gastrointestinal tract where most of the #Absorption, absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the pancreatic duct to aid in digestion. The small intestine is about long and folds many times to fit in the abdomen. Although it is longer than the large intestine, it is called the small intestine because it is narrower in diameter. The small intestine has three distinct regions – the duodenum, jejunum, and ileum. The duodenum, the shortest, is where preparation for absorption through small finger-like protrusions called intestinal villus, intestinal villi begins. The jejunum is specialized for the absorption through its lining by enterocytes: small nutrient particles which have been previously digested by enzymes in the duodenum. The main function of the ileum is to absorb vitami ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cytokines
Cytokines () are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Cytokines are produced by a broad range of cells, including immune cells like macrophages, B cell, B lymphocytes, T cell, T lymphocytes and mast cells, as well as Endothelium, endothelial cells, fibroblasts, and various stromal cells; a given cytokine may be produced by more than one type of cell. Due to their size, cytokines cannot cross the lipid bilayer of cells to enter the cytoplasm and therefore typically exert their functions by interacting with specific cytokine receptor, cytokine receptors on the target cell surface. Cytokines are especially important in the immune system; cytokines modulate the balance between humoral immunity, humoral and cell-mediated immunity, cell-based immune responses, and they regulate the maturation, growth, and responsiveness of particular cell populations. Some cytokines enhance or inhibit the action of other cytokines in complex way ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lactococcus Lactis
''Lactococcus lactis'' is a gram-positive bacterium used extensively in the production of buttermilk and cheese, but has also become famous as the first genetically modified organism to be used alive for the treatment of human disease. ''L. lactis'' cells are cocci that group in pairs and short chains, and, depending on growth conditions, appear ovoid with a typical length of 0.5 - 1.5 μm. ''L. lactis'' does not produce spores ( nonsporulating) and are not motile ( nonmotile). They have a homofermentative metabolism, meaning they produce lactic acid from sugars. They've also been reported to produce exclusive L-(+)- lactic acid. However, reported D-(−)-lactic acid can be produced when cultured at low pH. The capability to produce lactic acid is one of the reasons why ''L. lactis'' is one of the most important microorganisms in the dairy industry. Based on its history in food fermentation, ''L. lactis'' has generally recognized as safe (GRAS) status, with few case report ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lacticaseibacillus Casei
''Lacticaseibacillus casei'' is an organism that belongs to the largest genus in the family ''Lactobacillaceae'', a lactic acid bacteria (LAB), that was previously classified as ''Lactobacillus casei''. This bacteria has been identified as facultatively anaerobic or microaerophilic, acid-tolerant, non-spore-forming bacteria. This species is a non-sporing, rod-shaped, gram positive microorganism that can be found within the reproductive and digestive tract of the human body. Since ''L. casei'' can survive in a variety of environmental habitats, it has and continues to be extensively studied by health scientists. Commercially, ''L. casei'' is used in fermenting dairy products and its application as a probiotic. In bacteraemia, it is regarded to be similar in pathogenicity to Lactobacillus and associated with infective endocarditis. Taxonomy The taxonomy of the ''L. casei'' group has been debated for several years because researchers struggled to differentiate between the strain ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lactobacillus Acidophilus
''Lactobacillus acidophilus'' (Neo-Latin 'acid-loving milk-bacillus') is a rod-shaped, Gram-positive bacteria, Gram-positive, homofermentative, Anaerobic organism, anaerobic microbe first isolated from infant feces in the year 1900. The species is commonly found in humans, specifically the gastrointestinal tract and oral cavity as well as some speciality fermented foods such as fermented milk or yogurt, though it is not the most common species for this. The species most readily grows at low pH levels (below 5.0), and has an optimum growth temperature of 37 °C. Certain strains of ''L. acidophilus'' show strong probiotic effects, and are commercially used in dairy production. The genome of ''L. acidophilus'' has been sequenced. ''L. acidophilus'' has antagonistic effects on the growth of ''Staphylococcus aureus, Escherichia coli, Salmonella typhimurium,'' and ''Clostridium perfringens''. Out of the four organisms, ''Staphylococcus aureus'' is the most affected. Along with '' ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bifidobacterium Infantis
''Bifidobacterium longum'' is a Gram-positive, catalase-negative, rod-shaped bacterium present in the human gastrointestinal tract and one of the 32 species that belong to the genus ''Bifidobacterium''. It is a microaerotolerant anaerobe and considered to be one of the earliest colonizers of the gastrointestinal tract of infants. When grown on general anaerobic medium, ''B. longum'' forms white, glossy colonies with a convex shape. ''B. longum'' is one of the most common bifidobacteria present in the gastrointestinal tracts of both children and adults. ''B. longum'' is non-pathogenic, is often added to food products, and its production of lactic acid is believed to prevent growth of pathogenic organisms. Classification In 2002, three previously distinct species of ''Bifidobacterium'', ''B. infantis'', ''B. longum'', and ''B. suis'', were unified into a single species named ''B. longum'' with the biotypes ''infantis, longum,'' and ''suis'', respectively. This occurred as the thr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bifidobacterium Bifidum
''Bifidobacterium bifidum'' is a bacterial species of the genus '' Bifidobacterium''. ''B. bifidum'' is one of the most common probiotic bacteria that can be found in the body of mammals, including humans. Structure and characteristics ''B. bifidum'' is a Gram-positive, anaerobic bacterium that is neither motile nor spore-forming. The bacterium is rod-shaped and can be found living in clusters, pairs, or even independently. The majority of the population of ''B. bifidum'' is found in the colon, lower small intestine, breast milk, and often in the vagina. ''B. bifidum'' (along with ''B. longum'' and ''B. breve'') dominates in breastfed infants. With age, this composition alters in favor of other bifidobacteria species, and the total bifidobacteria population declines to lower but relatively stable levels. ''B. bifidum'' is an essential bacteria found in the human intestine. When it is low or absent all together in the human intestine, it is an indication of being in an un ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |