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Lemsip
Lemsip is a British brand of cold and flu remedies for treating people with cold, cough and flu by Reckitt, a UK-based consumer goods company. History Originally called LEM-SIP, the product was first introduced in 1969. In the 1970s, Reckitt rebranded the product to Lemsip and included the 'sword in a glass' logo on packaging. Products Their original and best-known product is the titular lemon-flavoured hot drink containing 650 mg of paracetamol (an analgesic), and 10 mg phenylephrine hydrochloride (a decongestant) to help to relieve headache, fever, blocked nose, body aches and pains, and a sore throat. In 1995 the Lemsip Max range was launched, which included lemon, blackcurrant and "Breathe Easy" hot drink flavours, and saw a variety of capsule products added to the range, including Lemsip Max Cold & Flu Capsules. The entire Lemsip Max range contains the maximum level of active ingredients allowed for general sales listing in the UK. In 2016 it was the four ...
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Guaifenesin
Guaifenesin, also known as glyceryl guaiacolate, sold under the brand name Mucinex, among others, is an expectorant medication taken by mouth and marketed as an aid to eliminate sputum from the respiratory tract. Chemically, it is an ether of guaiacol and glycerine. It may be used in combination with other medications. A 2014 study found that guaifenesin does not affect sputum volume in upper respiratory infections (the upper respiratory system includes most breathing parts ''above'' the lungs). It has been alleged to work in 2023 by making airway secretions more liquid. Side effects may include dizziness, sleepiness, skin rash, and nausea. While it has not been properly studied in pregnancy, it appears to be safe. Guaifenesin has been used medically since at least 1933. It is available as a generic medication and over-the-counter (OTC). In 2022, it was the 295th most commonly prescribed medication in the United States, with more than 400,000 prescriptions. In 2022, the com ...
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Common Cold
The common cold, or the cold, is a virus, viral infectious disease of the upper respiratory tract that primarily affects the Respiratory epithelium, respiratory mucosa of the human nose, nose, throat, Paranasal sinuses, sinuses, and larynx. Signs and symptoms may appear in as little as two days after exposure to the virus. These may include coughing, sore throat, rhinorrhea, runny nose, Sneeze, sneezing, headache, fatigue, and fever. People usually recover in seven to ten days, but some symptoms may last up to three weeks. Occasionally, those with other health problems may develop pneumonia. Well over 200 virus strains are implicated in causing the common cold, with rhinoviruses, coronaviruses, Adenoviridae, adenoviruses and enteroviruses being the most common. They spread through the air or indirectly through contact with objects in the environment, followed by transfer to the mouth or nose. Risk factors include going to child care facilities, Sleep deprivation, not sleepin ...
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Antipyretics
An antipyretic (, from ''anti-'' 'against' and ' 'feverish') is a substance that reduces fever. Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever. Most antipyretic medications have other purposes. The most common antipyretics in the US are usually ibuprofen and aspirin, which are nonsteroidal anti-inflammatory drugs (NSAIDs) used primarily as anti-inflammatories and analgesics (pain relievers), but which also have antipyretic properties; and paracetamol (acetaminophen), an analgesic without anti-inflammatory properties. There is some debate over the appropriate use of such medications, since fever is part of the body's immune response to infection. A study published by the Royal Society claims that fever suppression causes at least 1% more influenza deaths in the United States, or 700 extra deaths per year. Non-pharmacological treatment Bathing or ...
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Nottingham
Nottingham ( , East Midlands English, locally ) is a City status in the United Kingdom, city and Unitary authorities of England, unitary authority area in Nottinghamshire, East Midlands, England. It is located south-east of Sheffield and north-east of Birmingham. Nottingham is the legendary home of Robin Hood and to the lace-making, bicycle and Smoking in the United Kingdom, tobacco industries. The city is also the county town of Nottinghamshire and the settlement was granted its city charter in 1897, as part of Queen Victoria's Diamond Jubilee celebrations. In the 2021 United Kingdom census, 2021 Census, Nottingham had a reported population of 323,632. The wider conurbation, which includes many of the city's suburbs, has a population of 768,638. It is the largest urban area in the East Midlands and the second-largest in the Midlands. Its Functional Urban Area, the largest in the East Midlands, has a population of 919,484. The population of the Nottingham/Derby metropolitan a ...
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Kingston Upon Hull
Kingston upon Hull, usually shortened to Hull, is a historic maritime city and unitary authorities of England, unitary authority area in the East Riding of Yorkshire, England. It lies upon the River Hull at its confluence with the Humber Estuary, inland from the North Sea. It is a tightly bounded city which excludes the majority of its suburbs, with a population of (), it is the fourth-largest city in the Yorkshire and the Humber region. The built-up area has a population of 436,300. Hull has more than 800 years of seafaring history and is known as Yorkshire's maritime city. The town of Wyke on Hull was founded late in the 12th century by the monks of Meaux Abbey as a port from which to export their wool. Renamed ''Kings-town upon Hull'' in 1299, Hull had been a market town, military supply port, trading centre, fishing and whaling centre and industrial metropolis. Hull was an early theatre of battle in the First English Civil War, English Civil Wars. Its 18th-century ...
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Phenylephrine
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository. It can also be applied to the skin. Common side effects when taken by mouth or injected include nausea, vomiting, headache, and anxiety. Use on hemorrhoids is generally well tolerated. Severe side effects may include a slow heart rate, intestinal ischemia, chest pain, kidney failure, and tissue death at the site of injection. It is unclear whether its use during pregnancy and breastfeeding is safe. Phenylephrine is a selective α1-adrenergic receptor agonist with minimal to no β-adrenergic receptor agonist activity or induction of norepinephrine release. It causes constriction of both arteries and veins. Phenylephrine ...
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Kidney Damage
Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation. Inflammation can be diagnosed by blood tests. Nephrosis is non-inflammatory kidney disease. Nephritis and nephrosis can give rise to nephritic syndrome and nephrotic syndrome respectively. Kidney disease usually causes a loss of kidney function to some degree and can result in kidney failure, the complete loss of kidney function. Kidney failure is known as the end-stage of kidney disease, where dialysis or a kidney transplant is the only treatment option. Chronic kidney disease is defined as prolonged kidney abnormalities (functional and/or structural in nature) that last for more than three months. Acute kidney disease is now termed acute kidney injury and is marked by the sudden reduction in kidney function over seven days. Rates for both chronic kidne ...
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Liver Damage
Liver disease, or hepatic disease, is any of many diseases of the liver. If long-lasting it is termed chronic liver disease. Although the diseases differ in detail, liver diseases often have features in common. Liver diseases File:Ground glass hepatocytes high mag cropped 2.jpg, Ground glass hepatocytes File:Primary biliary cirrhosis intermed mag much cropping.jpg, Primary biliary cirrhosis File:Buddchiari2.PNG, Budd–Chiari syndrome File:Non-alcoholic_fatty_liver_disease1.jpg, Micrograph of non-alcoholic fatty liver disease There are more than a hundred different liver diseases. Some of the most common are: * Fascioliasis, a parasitic infection of liver caused by a liver fluke of the genus '' FascioIa'', mostly '' FascioIa hepatica''. * Hepatitis, inflammation of the liver, is caused by various viruses ( viral hepatitis) also by some liver toxins (e.g. alcoholic hepatitis), autoimmunity (autoimmune hepatitis) or hereditary conditions. * Alcoholic liver disease is a hepati ...
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Overdose
A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. Retrieved on September 20, 2014."Stairway to Recovery: Glossary of Terms"
. Retrieved on March 19, 2021
Typically the term is applied for cases when a risk to health is a potential result. An overdose may result in a toxicity, toxic state or death.


Classification

The word "overdose" implies that there is a common safe dosage and usage for the drug; therefore, the term is commonly applied only to drugs, not poisons, even though many poisons as well are harmless at a low enough dosage. Drug overdose is sometimes used as a means to commit suicide, as the result of intentional or unintentional misuse of medi ...
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Vomiting
Vomiting (also known as emesis, puking and throwing up) is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pregnancy, motion sickness, or hangover; or it can be an after effect of diseases such as brain tumors, elevated intracranial pressure, or overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea; it often precedes, but does not always lead to vomiting. Impairment due to alcohol or anesthesia can cause inhalation of vomit. In severe cases, where dehydration develops, intravenous fluid may be required. Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating disorder such as bulimia nervosa, and is itself now classified as an eating disorder on its own, purging disorder. Complications Aspiration Vomiting is dangerous if gastric content e ...
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Pancreatitis
Pancreatitis is a condition characterized by inflammation of the pancreas. The pancreas is a large organ behind the stomach that produces digestive enzymes and a number of hormone A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physio ...s. There are two main types, acute pancreatitis and chronic pancreatitis. Signs and symptoms of pancreatitis include epigastrium, pain in the upper abdomen, nausea, and vomiting. The pain often goes into the back and is usually severe. In acute pancreatitis, a fever may occur; symptoms typically resolve in a few days. In chronic pancreatitis, weight loss, steatorrhea, fatty stool, and diarrhea may occur. Complications may include infection, bleeding, diabetes mellitus, or problems with other organs. The two most common causes of acute pancreatitis ar ...
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Hypersensitivity
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to an antigen. It is an abnormality in the immune system that causes Immune disorder, immune diseases including allergies and autoimmunity. It is caused by many types of particles and substances from the external environment or from within the body that are recognized by the immune cells as antigens. The immune reactions are usually referred to as an over-reaction of the immune system and they are often damaging and uncomfortable. In 1963, Philip George Houthem Gell and Robin Coombs introduced a systematic classification of the different types of hypersensitivity based on the types of antigens and immune responses involved. According to this system, known as the #Gell and Coombs classification, Gell and Coombs classification or Gell-Coombs's classification, there are four types of hypersensitivity, namely: Typ ...
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