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Kupe Virus
Kupe virus is a species of virus in the genus ''Orthonairovirus''. History The virus was isolated from pooled ticks ('' Amblyomma gemma'' and ''Rhipicephalus pulchellus'') collected from cattle hides in Nairobi, Kenya, in October 1999.Sang R, Onyango C, Gachoya J, Mabinda E, Konongoi S, Ofula V, Dunster L, Okoth F, Coldren R, Tesh R, da Rossa AT, Finkbeiner S, Wang D, Crabtree M, Miller B (2006) Tickborne arbovirus surveillance in market livestock, Nairobi, Kenya. Emerg Infect Dis. 2006 Jul;12(7):1074-1080 The word 'Kupe' is Kiswahili for tick. Genome The genome is composed a single strand of negative sense RNA in three parts - small (S), medium (M0 and large(L). The L segment RNA is 12,330 nucleotides (nt) in length and encodes one open reading frame In molecular biology, reading frames are defined as spans of DNA sequence between the start and stop codons. Usually, this is considered within a studied region of a prokaryotic DNA sequence, where only one of the six possib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Orthonairovirus
''Orthonairovirus'' is a genus of viruses in the family '' Nairoviridae'' of the order '' Hareavirales'' which includes viruses with circular, negative-sense single stranded RNA. The name is derived from the Nairobi sheep disease which affects the gastrointestinal tracts of sheep and goats. All viruses in this genus are tick-borne viruses with human or other vertebrate hosts. Structure The virions for viruses in this genus have a spherical shape. They range in size from about 80–120 nm in diameter, with 50% of their weight attributed to proteins and 20–30% of their weight attributed to lipids. The ribonucleocapsid is filamentous, having a length of about 200-300 nm and a width of about 2–2.5 nm. These nucleocapsids are surrounded by a single envelope that has projections made of glycoproteins protruding from its surface. These projections evenly cover the surface of the virion, and are about 5–10 nm long. They aid in attachment to the host r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tick
Ticks are parasitic arachnids of the order Ixodida. They are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, and species, but can become larger when engorged. Ticks are external parasites, living by feeding on the blood of mammals, birds, and sometimes reptiles and amphibians. The timing of the origin of ticks is uncertain, though the oldest known tick fossils are around 100 million years old, and come from the Cretaceous period. Ticks are widely distributed around the world, especially in warm, humid climates. Ticks belong to two major families: the Ixodidae, or hard ticks, and the Argasidae, or soft ticks. '' Nuttalliella'', a genus of tick from southern Africa, is the only member of the family Nuttalliellidae, and represents the most primitive living lineage of ticks. Adults have ovoid/pear-shaped bodies (idiosomas) which become engorged with blood when they feed, and eight legs. Their cephalotho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amblyomma Gemma
''Amblyomma'' is a genus of hard ticks. Some are disease vectors, for example the Rocky Mountain spotted fever in United States or ehrlichiosis in Brazil. This genus is the third largest in the family Ixodidae, with its species primarily occupying the torrid zones of all the continents. The centre of species diversity is on the American continent, where half of all the species occur. On this continent, ''Amblyomma'' species reach far beyond the torrid zone, up to the 40th parallel in the Northern Hemisphere, to the 50th parallel in the Southern Hemisphere, and even reaches the alpine zone of the Andes. They also occur in Eurasia, Africa and Australia. G. V. Kolonin, Fauna of Ixodid Ticks of the World (Acari, Ixodidae), Moscow 2009 Species * '' ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhipicephalus Pulchellus
The zebra tick or yellow back tick (''Rhipicephalus pulchellus'') is a species of hard tick. It is common in the Horn of Africa, with a habitat of the East African Rift, Rift Valley and eastward. It feeds upon a wide variety of species, including livestock, wild mammals, and humans, and can be a vector (epidemiology), vector for various pathogens. The adult male has a distinctive black and ivory ornamentation on its Scute#Insects and other arthropods, scutum. Taxonomy and names ''Rhipicephalus pulchellus'' was species description, described by Carl Eduard Adolph Gerstaecker, who initially placed it in the genus ''Dermacentor'' due to the ornamentation; all ''Dermacentor'' ticks are ornate. Its syntypes are at the Museum für Naturkunde. transferred this species to ''Rhipicephalus'' in 1897. R. I. Pocock described a junior synonym, ''R. marmoreus'', in 1900; its holotype was deposited at the Natural History Museum, London. By 1901, Neumann had synonymized it with ''R. pulchellus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nairobi
Nairobi is the Capital city, capital and largest city of Kenya. The city lies in the south-central part of Kenya, at an elevation of . The name is derived from the Maasai language, Maasai phrase , which translates to 'place of cool waters', a reference to the Nairobi River which flows through the city. The city proper had a population of 4,397,073 in the 2019 census. Nairobi is home of the Parliament Buildings (Kenya), Kenyan Parliament Buildings and hosts thousands of Kenyan businesses and international companies and organisations, including the United Nations Environment Programme (UN Environment) and the United Nations Office at Nairobi (UNON). Nairobi is an established hub for business and culture. The Nairobi Securities Exchange (NSE) is one of the largest stock exchanges in Africa and the second-oldest exchange on the continent. It is Africa's fourth-largest stock exchange in terms of trading volume, capable of making 10 million trades a day. It also contains the Nairobi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kenya
Kenya, officially the Republic of Kenya, is a country located in East Africa. With an estimated population of more than 52.4 million as of mid-2024, Kenya is the 27th-most-populous country in the world and the 7th most populous in Africa. Kenya's capital and largest city is Nairobi. Its second-largest and oldest city is Mombasa, a major port city located on Mombasa Island. Other major cities within the country include Kisumu, Nakuru & Eldoret. Going clockwise, Kenya is bordered by South Sudan to the northwest (though much of that border includes the disputed Ilemi Triangle), Ethiopia to the north, Somalia to the east, the Indian Ocean to the southeast, Tanzania to the southwest, and Lake Victoria and Uganda to the west. Kenya's geography, climate and population vary widely. In western, rift valley counties, the landscape includes cold, snow-capped mountaintops (such as Batian, Nelion and Point Lenana on Mount Kenya) with vast surrounding forests, wildlife and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kiswahili
Swahili, also known as as it is referred to in the Swahili language, is a Bantu language originally spoken by the Swahili people, who are found primarily in Tanzania, Kenya, and Mozambique (along the East African coast and adjacent littoral islands). Estimates of the number of Swahili speakers, including both native and second-language speakers, vary widely. They generally range from 150 million to 200 million; with most of its native speakers residing in Tanzania and Kenya. Swahili has a significant number of loanwords from other languages, mainly Arabic, as well as from Portuguese, English and German. Around 40% of Swahili vocabulary consists of Arabic loanwords, including the name of the language ( , a plural adjectival form of an Arabic word meaning 'of the coasts'). The loanwords date from the era of contact between Arab traders and the Bantu inhabitants of the east coast of Africa, which was also the time period when Swahili emerged as a lingua franca in the region. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleotide
Nucleotides are Organic compound, organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all Life, life-forms on Earth. Nucleotides are obtained in the diet and are also synthesized from common Nutrient, nutrients by the liver. Nucleotides are composed of three subunit molecules: a nucleobase, a pentose, five-carbon sugar (ribose or deoxyribose), and a phosphate group consisting of one to three phosphates. The four nucleobases in DNA are guanine, adenine, cytosine, and thymine; in RNA, uracil is used in place of thymine. Nucleotides also play a central role in metabolism at a fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP), cytidine triphosphate (CTP), and uridine triph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Reading Frame
In molecular biology, reading frames are defined as spans of DNA sequence between the start and stop codons. Usually, this is considered within a studied region of a prokaryotic DNA sequence, where only one of the six possible reading frames will be "open" (the "reading", however, refers to the RNA produced by transcription of the DNA and its subsequent interaction with the ribosome in translation). Such an open reading frame (ORF) may contain a start codon (usually AUG in terms of RNA) and by definition cannot extend beyond a stop codon (usually UAA, UAG or UGA in RNA). That start codon (not necessarily the first) indicates where translation may start. The transcription termination site is located after the ORF, beyond the translation stop codon. If transcription were to cease before the stop codon, an incomplete protein would be made during translation. In eukaryotic genes with multiple exons, introns are removed and exons are then joined together after transcription to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
