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Kevin Johnson (venture Capitalist)
Kevin Johnson (born 30 August 1960 in Holyhead, Wales) is a partner at medicxi, a venture capital firm focused on life sciences investments based on the asset-centric approach to investing. He was formerly with Index Ventures, having joined the venture capital firm in 2010. Education and career Johnson graduated in Molecular Biology from Edinburgh University and has a PhD in Pathology from Cambridge University. From 1990 onwards, Johnson was one of the team at Cambridge Antibody Technology (CAT), heading up research and in 1997 he was appointed to the board, where he held the posts of Research Director and Chief Technology Officer. Kevin led both the development of CAT's platform technologies, and also their application to the discovery of a number of human antibodies currently in clinical development, including the first such drug, Humira to reach the market. He was also part of the management team that floated CAT on the London Stock Exchange (main market). Johnson was CEO ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Holyhead
Holyhead (; , "Cybi's fort") is a historic port town, and is the list of Anglesey towns by population, largest town and a Community (Wales), community in the county of Isle of Anglesey, Wales. Holyhead is on Holy Island, Anglesey, Holy Island, bounded by the Irish Sea to the north, and is separated from Anglesey island by the narrow Cymyran Strait, having originally been connected to Anglesey via the Four Mile Bridge#The Bridge, Four Mile Bridge. In the mid-19th century, John Stanley, 1st Baron Stanley of Alderley, Lord Stanley, a local philanthropist, funded the building of a larger Stanley Embankment, causeway, known locally as "the Cobb". it now carries the A5 road (Great Britain), A5 and the North Wales Coast Line, railway line. The A55 road (Great Britain), A55 dual carriageway runs parallel to the Cobb on a modern causeway. The town houses the Port of Holyhead, a major Irish Sea port for connections towards Ireland. The population of the town proper as of the 2021 censu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wales
Wales ( ) is a Countries of the United Kingdom, country that is part of the United Kingdom. It is bordered by the Irish Sea to the north and west, England to the England–Wales border, east, the Bristol Channel to the south, and the Celtic Sea to the south-west. , it had a population of 3.2 million. It has a total area of and over of Coastline of Wales, coastline. It is largely mountainous with its higher peaks in the north and central areas, including Snowdon (), its highest summit. The country lies within the Temperate climate, north temperate zone and has a changeable, Oceanic climate, maritime climate. Its capital and largest city is Cardiff. A distinct Culture of Wales, Welsh culture emerged among the Celtic Britons after the End of Roman rule in Britain, Roman withdrawal from Britain in the 5th century, and Wales was briefly united under Gruffudd ap Llywelyn in 1055. After over 200 years of war, the Conquest of Wales by Edward I, conquest of Wales by King Edward I o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Venture Capital
Venture capital (VC) is a form of private equity financing provided by firms or funds to start-up company, startup, early-stage, and emerging companies, that have been deemed to have high growth potential or that have demonstrated high growth in terms of number of employees, annual revenue, scale of operations, etc. Venture capital firms or funds invest in these early-stage companies in exchange for Equity (finance), equity, or an ownership stake. Venture capitalists take on the risk of financing start-ups in the hopes that some of the companies they support will become successful. Because Startup company, startups face high uncertainty, VC investments have high rates of failure. Start-ups are usually based on an innovation, innovative technology or business model and often come from high technology industries such as information technology (IT) or biotechnology. Pre-seed and seed money, seed rounds are the initial stages of funding for a startup company, typically occurring earl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Life Sciences
This list of life sciences comprises the branches of science that involve the scientific study of life – such as microorganisms, plants, and animals including human beings. This science is one of the two major branches of natural science, the other being physical science, which is concerned with non-living matter. Biology is the overall natural science that studies life, with the other life sciences as its sub-disciplines. Some life sciences focus on a specific type of organism. For example, zoology is the study of animals, while botany is the study of plants. Other life sciences focus on aspects common to all or many life forms, such as anatomy and genetics. Some focus on the micro-scale (e.g. molecular biology, biochemistry) other on larger scales (e.g. cytology, immunology, ethology, pharmacy, ecology). Another major branch of life sciences involves understanding the mindneuroscience. Life sciences discoveries are helpful in improving the quality and standard of life ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Index Ventures
Index Ventures is a European venture capital firm with headquarters in both San Francisco and London. It invests primarily in tech companies. History Index Ventures has its origins in a Switzerland, Swiss bond (finance), bond-trading firm called Index Securities, founded by Gerald Rimer in 1976. In 1992, Rimer recruited his son Neil to join the firm, launching a technology investment arm that evolved into Index Ventures. Index Ventures was officially founded in 1996 by Neil Rimer, David Rimer and Giuseppe Zocco. It began investing in Israel in 2003, and by 2005 raised €300 million for its third fund. Two years later, it raised an additional €350 million for its fourth found, which focused 15 to 20 percent on investing in Israeli companies. The sixth fund raised €350 million from investors in 2012 and focused on investments in Europe, the United States, U.S., and Israeli tech startups. In 2017, it raised €400 million for its seventh fund, focusing on companies in Europ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edinburgh University
The University of Edinburgh (, ; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Founded by the town council under the authority of a royal charter from King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played a crucial role in Edinburgh becoming a leading intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the " Athens of the North". The three main global university rankings ( ARWU, THE, and QS) place the University of Edinburgh within their respective top 40. It is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2024, the university had a total ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cambridge University
The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, world's third-oldest university in continuous operation. The university's founding followed the arrival of scholars who left the University of Oxford for Cambridge after a dispute with local townspeople. The two ancient university, ancient English universities, although sometimes described as rivals, share many common features and are often jointly referred to as Oxbridge. In 1231, 22 years after its founding, the university was recognised with a royal charter, granted by Henry III of England, King Henry III. The University of Cambridge includes colleges of the University of Cambridge, 31 semi-autonomous constituent colleges and List of institutions of the University of Cambridge#Schools, Faculties, and Departments, over 150 academic departm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cambridge Antibody Technology
Cambridge Antibody Technology Group Plc, (commonly referred to as CAT) was a biotechnology company headquartered in Cambridge, England. Its core focus was on antibody therapeutics, primarily using phage display, Phage Display and ribosome display, Ribosome Display technology. Phage display, Phage Display Technology was used by CAT to create adalimumab, the first fully human antibody blockbuster drug. Humira, the brand name of adalimumab, is an anti-TNF antibody discovered by CAT as D2E7, then developed in the clinic and marketed by Abbvie, formerly Abbott Laboratories. CAT was also behind belimumab, the anti-BlyS antibody drug marketed as Benlysta and the first new approved drug for systemic lupus in more than 50 years. In 2018, the Nobel Prize organisation awarded one quarter of the Nobel Prize in Chemistry to a founding member of CAT, Greg Winter, Sir Greg Winter FRS "for the phage display of peptides and antibodies". Founded in 1989, CAT was acquired by AstraZeneca for £702 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process—from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials—to approved vaccine or drug typically takes more than a decade. New chemical entity development Broadly, the process of drug development can be divided into preclinical and clinical work. Pre-clinical New chemical entities (NCEs, also known as new molecular entities or NMEs) are compounds that emerge from the process of drug discovery. These have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humira
Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis. It is administered by subcutaneous injection (injection under the skin). It works by inactivating tumor necrosis factor-alpha ( TNFα). Common side effects include upper respiratory tract infections, pain at the site of injection, rash, and headache. Other side effects may include serious infections, cancer, anaphylaxis, reactivation of hepatitis B, new onset or exacerbation of demyelinating diseases (such as multiple sclerosis), heart failure, liver failure, and aplastic anemia. Use during pregnancy is not recommended, but some sources show use during breastfeeding may be safe. Adalimumab was approved for medical use in the United States in 2002. It ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
London Stock Exchange
The London Stock Exchange (LSE) is a stock exchange based in London, England. the total market value of all companies trading on the LSE stood at US$3.42 trillion. Its current premises are situated in Paternoster Square close to St Paul's Cathedral. Since 2007, it has been part of the London Stock Exchange Group (LSEG, which the exchange also lists (ticker symbol LSEG)). Despite a post-Brexit exodus of stock listings from the LSE, it was the most valued stock exchange in Europe as of 2023. According to the 2020 Office for National Statistics report, approximately 12% of UK-resident individuals reported having investments in stocks and shares. According to a 2020 Financial Conduct Authority report, approximately 15% of British adults reported having investments in stocks and shares. History Coffee House The Royal Exchange, London, Royal Exchange had been founded by the English financier Thomas Gresham and Sir Richard Clough on the model of the The Belgian bourse of Antwerp, An ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
