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Jonathan Betts-LaCroix
Jonathan "Joe" Betts-LaCroix (born Jonathan Betts; February 26, 1962) is an American scientist and entrepreneur known for his discoveries in biophysics and for creating the world's smallest personal computer. He is working to optimize medical research priorities in the U.S. Early life and education Joe Betts-LaCroix was born and raised in Oregon. He graduated from school with a D average, then spent the next six years living in a shared house with others whom he described as, "musicians, artists and weirdos". At this time, he did electronics, hardware and software work for local businesses. When his girlfriend went to Harvard, he decided to follow. After getting straight A's at a local college, he transferred to Harvard, where he studied environmental geoscience. Academics Beginning in earth sciences at Harvard, Betts-LaCroix contributed to the field of long-term regulation of oxygen on Earth over multi-100 Million-year timespans, quantifying the effect of the burial efficienc ...
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Seattle
Seattle ( ) is the most populous city in the U.S. state of Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the 18th-most populous city in the United States. The city is the county seat of King County, the most populous county in Washington. The Seattle metropolitan area's population is 4.02 million, making it the 15th-most populous in the United States. Its growth rate of 21.1% between 2010 and 2020 made it one of the country's fastest-growing large cities. Seattle is situated on an isthmus between Puget Sound, an inlet of the Pacific Ocean, and Lake Washington. It is the northernmost major city in the United States, located about south of the Canadian border. A gateway for trade with East Asia, the Port of Seattle is the fourth-largest port in North America in terms of container handling . The Seattle area has been inhabited by Native Americans (such as the Duwamish, who had at least 17 villages a ...
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Electron Microscopy
An electron microscope is a microscope that uses a beam of electrons as a source of illumination. It uses electron optics that are analogous to the glass lenses of an optical light microscope to control the electron beam, for instance focusing it to produce magnified images or electron diffraction patterns. As the wavelength of an electron can be up to 100,000 times smaller than that of visible light, electron microscopes have a much higher resolution of about 0.1 nm, which compares to about 200 nm for light microscopes. ''Electron microscope'' may refer to: * Transmission electron microscope (TEM) where swift electrons go through a thin sample * Scanning transmission electron microscope (STEM) which is similar to TEM with a scanned electron probe * Scanning electron microscope (SEM) which is similar to STEM, but with thick samples * Electron microprobe similar to a SEM, but more for chemical analysis * Low-energy electron microscope (LEEM), used to image surfaces * ...
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Massachusetts Institute Of Technology Alumni
Massachusetts ( ; ), officially the Commonwealth of Massachusetts, is a U.S. state, state in the New England region of the Northeastern United States. It borders the Atlantic Ocean and the Gulf of Maine to its east, Connecticut and Rhode Island to its south, New Hampshire and Vermont to its north, and New York (state), New York to its west. Massachusetts is the List of U.S. states and territories by area, sixth-smallest state by land area. With a 2024 U.S. Census Bureau-estimated population of 7,136,171, its highest estimated count ever, Massachusetts is the most populous state in New England, the List of U.S. states and territories by population, 16th-most-populous in the United States, and the List of states and territories of the United States by population density, third-most densely populated U.S. state, after New Jersey and Rhode Island. Massachusetts was a site of early British colonization of the Americas, English colonization. The Plymouth Colony was founded in 16 ...
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Harvard College Alumni
The list of Harvard University alumni includes notable graduates, professors, and administrators affiliated with Harvard University. For a list of notable non-graduates of Harvard, see the list of Harvard University non-graduate alumni. For a list of Harvard's presidents, see President of Harvard University. Eight Presidents of the United States have graduated from Harvard University: John Adams, John Quincy Adams, Rutherford B. Hayes, John F. Kennedy, Franklin Delano Roosevelt, Theodore Roosevelt, George W. Bush, and Barack Obama. Bush graduated from Harvard Business School, Hayes and Obama from Harvard Law School, and the others from Harvard College. Over 150 Nobel Prize winners have been associated with the university as alumni, researchers or faculty. Nobel laureates Pulitzer Prize winners ...
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Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ...
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1962 Births
The year saw the Cuban Missile Crisis, which is often considered the closest the world came to a Nuclear warfare, nuclear confrontation during the Cold War. Events January * January 1 – Samoa, Western Samoa becomes independent from New Zealand. * January 3 – The office of Pope John XXIII announces the excommunication of Fidel Castro for preaching communism and interfering with Catholic churches in Cuba. * January 8 – Harmelen train disaster: 93 die in the worst Netherlands, Dutch rail disaster. * January 9 – Cuba and the Soviet Union sign a trade pact. * January 12 – The Indonesian Army confirms that it has begun operations in West Irian. * January 13 – People's Socialist Republic of Albania, Albania allies itself with the People's Republic of China. * January 15 ** Portugal abandons the United Nations General Assembly due to the debate over Angola. ** French designer Yves Saint Laurent (designer), Yves Saint Laurent launches Yves Saint Lau ...
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Aging-associated Diseases
An aging-associated disease (commonly termed age-related disease, ARD) is a disease that is most often seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself because all adult animals age ( with rare exceptions) but not all adult animals experience all age-associated diseases. The term does not refer to age-specific diseases, such as the childhood diseases chicken pox and measles, only diseases of the elderly. They are also not accelerated aging diseases, all of which are genetic disorders. Examples of aging-associated diseases are atherosclerosis and cardiovascular disease, cancer, arthritis, cataracts, osteoporosis, type 2 diabetes, hypertension and Alzheimer's disease. The incidence of all of these diseases increases exponentially with age. Of the roughly 150,000 people who die each day across the globe, about two thirds—100,000 per day—die of age-related causes. In ...
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Autophagy
Autophagy (or autophagocytosis; from the Greek language, Greek , , meaning "self-devouring" and , , meaning "hollow") is the natural, conserved degradation of the cell that removes unnecessary or dysfunctional components through a lysosome-dependent regulated mechanism. It allows the orderly degradation and recycling of cellular components. Although initially characterized as a primordial degradation pathway induced to protect against starvation, it has become increasingly clear that autophagy also plays a major role in the homeostasis of non-starved cells. Defects in autophagy have been linked to various human diseases, including neurodegeneration and cancer, and interest in modulating autophagy as a potential treatment for these diseases has grown rapidly. Four forms of autophagy have been identified: macroautophagy, microautophagy, chaperone-mediated autophagy (CMA), and crinophagy. In macroautophagy (the most thoroughly researched form of autophagy), cytoplasmic components ( ...
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Sam Altman
Samuel Harris Altman (born April 22, 1985) is an American technology entrepreneur, investor, and the chief executive officer of OpenAI since 2019 (he was Removal of Sam Altman from OpenAI, briefly dismissed and reinstated in November 2023). He is considered one of the leading figures of the AI boom. Altman dropped out of Stanford University after two years and founded Loopt, a mobile social networking service, raising more than $30million in venture capital. In 2011, Altman joined Y Combinator, a startup accelerator, and was its president from 2014 to 2019. He has served as Chair (officer), chairman of clean energy companies Helion Energy and Oklo Inc., Oklo (until April 2025). Altman's net worth was estimated at $1.8billion as of June 2025. Early life and education Altman was born on April 22, 1985, in Chicago, Illinois, into a Jewish family, and grew up in St. Louis, Missouri. His mother was a dermatologist, and his father a real estate broker. Altman is the eldest of four ...
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OpenAI
OpenAI, Inc. is an American artificial intelligence (AI) organization founded in December 2015 and headquartered in San Francisco, California. It aims to develop "safe and beneficial" artificial general intelligence (AGI), which it defines as "highly autonomous systems that outperform humans at most economically valuable work". As a leading organization in the ongoing AI boom, OpenAI is known for the GPT family of large language models, the DALL-E series of text-to-image models, and a text-to-video model named Sora (text-to-video model), Sora. Its release of ChatGPT in November 2022 has been credited with catalyzing widespread interest in generative AI. The organization has a complex corporate structure. As of April 2025, it is led by the Nonprofit organization, non-profit OpenAI, Inc., Delaware General Corporation Law, registered in Delaware, and has multiple for-profit subsidiaries including OpenAI Holdings, LLC and OpenAI Global, LLC. Microsoft has invested US$13 billion ...
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Y Combinator
Y Combinator, LLC (YC) is an American technology startup accelerator and venture capital firm launched in March 2005 which has been used to launch more than 5,000 companies. The accelerator program started in Boston and Mountain View, California, Mountain View, expanded to San Francisco in 2019, and was entirely online during the COVID-19 pandemic. Companies started via Y Combinator include Airbnb, Coinbase, Cruise (autonomous vehicle), Cruise, DoorDash, Dropbox (service), Dropbox, Instacart, Reddit, Stripe (company), Stripe, Scale AI, Deel (company), Deel, Helion Energy, and Twitch (service), Twitch. History Founded in 2005 by Paul Graham (programmer), Paul Graham, Jessica Livingston, Robert Tappan Morris, and Trevor Blackwell, Y Combinator (YC) initiated operations with concurrent programs in Cambridge, Massachusetts, and Mountain View, California. However, operational complexities arising from managing two programs prompted a consolidation in January 2009, resulting in the cl ...
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AbbVie Inc
AbbVie Inc. is an American pharmaceutical company headquartered in North Chicago, Illinois. It is ranked sixth on the list of largest biomedical companies by revenue. In 2023, the company's seat in Forbes Global 2000 was 74, and rank 89 on the 2024 list. The company's primary product is Humira (adalimumab) ($14billion in 2023 revenues, 27percent of total), administered via injection. It is approved to treat autoimmune diseases including rheumatoid arthritis, Crohn's disease, plaque psoriasis, and ulcerative colitis. It developed Skyrizi ($7.8billion in 2023 revenues), an interleukin-23 (IL-23) inhibitor also used to treat autoimmune diseases. Its other major products include Botox ($5.7billion in 2023 revenues), Imbruvica to treat cancer ($3.6billion in 2023 revenues), Rinvoq to treat arthritis ($4billion in 2023 revenues), Venclexta to treat leukemia and lymphoma ($2.3billion in 2023 revenues), Vraylar to treat schizophrenia and bipolar disorder ($2.7billion in 2023 revenues), a ...
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