|
Joffroy's Sign
Joffroy's sign is a clinical sign in which there is a lack of wrinkling of the forehead when a patient looks up with the head bent forwards. It occurs in patients with exophthalmos in Graves disease Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyro .... The sign is named after Alexis Joffroy. References External links Symptoms and signs: Endocrinology, nutrition, and metabolism {{med-sign-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Sign
Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition. A sign for example may be a higher or lower temperature than normal, raised or lowered blood pressure or an abnormality showing on a medical scan. A symptom is something out of the ordinary that is experienced by an individual such as feeling feverish, a headache or other pain or pains in the body. Signs and symptoms Signs A medical sign is an objective observable indication of a disease, injury, or abnormal physiological state that may be detected during a physical examination, examining the patient history, or diagnostic procedure. These signs are visible or otherwise detectable such as a rash or bruise. Medical signs, along with symptoms, assist in formulating diagnostic hypothesis. Examples of signs include elevated blood pressure, nail clubbing of the fingernails or toenails, staggering gait, and arcus senilis and arcus juvenilis of the eyes. Ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exophthalmos
Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or swelling of surrounding tissue resulting from trauma. In the case of Graves' disease, the displacement of the eye results from abnormal connective tissue deposition in the orbit and extraocular muscles, which can be visualized by CT or MRI. If left untreated, exophthalmos can cause the eyelids to fail to close during sleep, leading to corneal dryness and damage. Another possible complication is a form of redness or irritation called superior limbic keratoconjunctivitis, in which the area above the cornea becomes inflamed as a result of increased friction when blinking. The process that is causing the displacement of the eye may also compr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Graves Disease
Graves' disease (german: Morbus Basedow), also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyroid. Signs and symptoms of hyperthyroidism may include irritability, muscle weakness, sleeping problems, a fast heartbeat, poor tolerance of heat, diarrhea and unintentional weight loss. Other symptoms may include thickening of the skin on the shins, known as pretibial myxedema, and eye bulging, a condition caused by Graves' ophthalmopathy. About 25 to 30% of people with the condition develop eye problems. The exact cause of the disease is unclear; however, it is believed to involve a combination of genetic and environmental factors. A person is more likely to be affected if they have a family member with the disease. If one twin is affected, a 30% chance exists that the other twin will also have the disease. The onset of disease may be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexis Joffroy
Alix Joffroy (16 December 1844, in Stainville – 24 November 1908) was a French neurologist and psychiatrist remembered for describing Joffroy's sign. He studied in Paris, earning his doctorate in 1873, becoming médecin des hôpitaux in 1879 and agrégé in 1880. He worked at the Pitié-Salpêtrière Hospital from 1885 and succeeded Benjamin Ball as professor of clinical psychiatry in 1893. Jean-Martin Charcot encouraged him to study neurology, and together they demonstrated atrophy of anterior horn cells in the spinal cord in poliomyelitis in 1869. See also * A Clinical Lesson at the Salpêtrière ''A Clinical Lesson at the Salpêtrière'' (french: Une leçon clinique à la Salpêtrière) is an 1887 group tableau portrait painted by the history and genre artist André Brouillet (1857–1914). The painting, one of the best-known in the his ... External links * French neurologists French psychiatrists 1844 births 1908 deaths {{France-psychiatrist-stu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.jpg "Click for more on -> Graves Disease")
