Jacques Dubochet
Jacques Dubochet (born 8 June 1942) is a retired Swiss biophysicist. He is a former researcher at the European Molecular Biology Laboratory in Heidelberg, Germany, and an honorary professor of biophysics at the University of Lausanne in Switzerland. In 2017, he received the Nobel Prize in Chemistry together with Joachim Frank and Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution". He received the Royal Photographic Society Progress Medal, alongside his colleagues Professor Joachim Frank and Dr Richard Henderson, in 2018 for 'an important advance in the scientific or technological development of photography or imaging in the widest sense'. Career Dubochet started to study physics at the ''École polytechnique de l'Université de Lausanne'' (now École polytechnique fédérale de Lausanne) in 1962 and obtained his degree in physical engineering in 1967. He obtained a Certificate of Molecula ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Aigle
, neighboring_municipalities= Vaud: Yvorne, Leysin, Ormont-Dessous, Ollon; Valais: Vouvry, Collombey-Muraz , twintowns = L'Aigle (France), Tübingen (Germany), Bassersdorf (Switzerland) } Aigle (French for "eagle", ; frp, Âgllo) is a historic town and a municipality and the capital of the district of Aigle in the canton of Vaud in Switzerland. The official language of Aigle is Swiss French. Geography Aigle lies at an elevation of about south-southeast of Montreux. It is on the east edge of the Rhône valley, at the foot of the Swiss Alps. Aigle has an area, , of . Of this area, or 34.1% is used for agricultural purposes, while or 37.4% is forested. Of the rest of the land, or 25.6% is settled (buildings or roads), or 2.7% is either rivers or lakes and or 0.6% is unproductive land. [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Joachim Frank
Joachim Frank () (born September 12, 1940) is a German-American biophysicist at Columbia University and a Nobel laureate. He is regarded as the founder of single-particle cryo-electron microscopy (cryo-EM), for which he shared the Nobel Prize in Chemistry in 2017 with Jacques Dubochet and Richard Henderson. He also made significant contributions to structure and function of the ribosome from bacteria and eukaryotes. Life and career Frank was born in Siegen in the borough of Weidenau. After completing his Vordiplom (B.S.) degree in physics at the University of Freiburg (1963) and his Diplom under Walter Rollwagen's mentorship at the Ludwig Maximilian University of Munich with the thesis "Untersuchung der Sekundärelektronen-Emission von Gold am Schmelzpunkt" (Investigation of secondary electron emission of gold at its melting point) (1967), Frank obtained his Ph.D. from the Technical University of Munich for graduate studies in Walter Hoppe's lab at the Max Planck Institut ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vitrification
Vitrification (from Latin ''vitreum'', "glass" via French ''vitrifier'') is the full or partial transformation of a substance into a glass, that is to say, a non-crystalline amorphous solid. Glasses differ from liquids structurally and glasses possess a higher degree of connectivity with the same Hausdorff dimensionality of bonds as crystals: dimH = 3. In the production of ceramics, vitrification is responsible for its impermeability to water. Vitrification is usually achieved by heating materials until they liquidize, then cooling the liquid, often rapidly, so that it passes through the glass transition to form a glassy solid. Certain chemical reactions also result in glasses. In terms of chemistry, vitrification is characteristic for amorphous materials or disordered systems and occurs when bonding between elementary particles (atoms, molecules, forming blocks) becomes higher than a certain threshold value. Thermal fluctuations break the bonds; therefore, the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lennart Philipson
Carl Lennart Philipson (July 16, 1929 – June 26, 2011) was a Swedish virologist and professor at Karolinska Institute. He is well known for his research in respiratory viruses and his direction over several research institutions. Career Philipson earned his MD in 1957 and PhD in 1958 at Uppsala University, working with Arne Tiselius. He came to the United States in 1959 to do a postdoc at the Rockefeller University in virology, before returning to Sweden's Uppsala University to establish his own laboratory in 1961 with Jan Pontén. He did two sabbaticals in the United States. In 1971 in the laboratory of Jim Darnell, and in 1977 in the laboratory of David Baltimore. In 1967, he was appointed director of the Wallenberg Laboratory in Sweden. In 1982, he was appointed to be the second director general of the European Molecular Biology Laboratory (EMBL), which he ran until 1993. He resigned after being unable to convince the council to increase the funding by 15-20% each year. A ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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EMBO Reports
''EMBO Reports'' is a peer-reviewed scientific journal covering research related to biology at a molecular level. It publishes primary research papers, reviews, and essays and opinion. It also features commentaries on the social impact of advances in the life sciences and the converse influence of society on science. A sister journal to '' The EMBO Journal'', ''EMBO Reports'' was established in 2000 and was published on behalf of the European Molecular Biology Organization by Nature Publishing Group since 2003. It is now published by EMBO Press Embo ( gd, Eurabol, IPA: �iaɾəpɔɫ̪ is a village in the Highland Council Area in Scotland and the former postal county of Sutherland, about north-northeast of Dornoch. On 16 July 1988, Embo declared itself independent from the rest of the .... External links * Molecular biology Molecular and cellular biology journals Monthly journals English-language journals Publications established in 2000 European Molecular Biology Org ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Protein Complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains. Protein complexes are distinct from multienzyme complexes, in which multiple catalytic domains are found in a single polypeptide chain. Protein complexes are a form of quaternary structure. Proteins in a protein complex are linked by non-covalent protein–protein interactions. These complexes are a cornerstone of many (if not most) biological processes. The cell is seen to be composed of modular supramolecular complexes, each of which performs an independent, discrete biological function. Through proximity, the speed and selectivity of binding interactions between enzymatic complex and substrates can be vastly improved, leading to higher cellular efficiency. Many of the techniques used to enter cells and isolate proteins are inherently disruptive to such large complexes, complicating the task of determining the components of a complex. Examples of protein complexes include th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Journal Of Microscopy
The ''Journal of Microscopy'' is the monthly peer-reviewed scientific journal of the Royal Microscopical Society which covers all aspects of microscopy including spatially resolved spectroscopy, compositional mapping, and image analysis. This includes technology and applications in physics, chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ..., material science, and the life sciences. It is published by Wiley-Blackwell on behalf of the Society. The editor-in-chief is Michelle Peckham, a Cell Biology professor at University of Leeds. The journal publishes review articles, original research papers, short communications, and letters to the editor. It was established in 1841 as the ''Transactions of the Microscopical Society of London'', obtaining its current name in 1869, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cryo-electron Tomography
Electron cryotomography (CryoET) is an imaging technique used to produce high-resolution (~1–4 nm) three-dimensional views of samples, often (but not limited to) biological macromolecules and cells. CryoET is a specialized application of transmission electron cryomicroscopy (CryoTEM) in which samples are imaged as they are tilted, resulting in a series of 2D images that can be combined to produce a 3D reconstruction, similar to a CT scan of the human body. In contrast to other electron tomography techniques, samples are imaged under cryogenic conditions (< −150 °C). For cellular material, the structure is immobilized in non-crystalline, vitreous ice, allowing them to be imaged without dehydration or chemical fixation, which would otherwise disrupt or distort biological structures. Description of technique [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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West Germany
West Germany is the colloquial term used to indicate the Federal Republic of Germany (FRG; german: Bundesrepublik Deutschland , BRD) between its formation on 23 May 1949 and the German reunification through the accession of East Germany on 3 October 1990. During the Cold War, the western portion of Germany and the associated territory of West Berlin were parts of the Western Bloc. West Germany was formed as a political entity during the Allied occupation of Germany after World War II, established from eleven states formed in the three Allied zones of occupation held by the United States, the United Kingdom, and France. The FRG's provisional capital was the city of Bonn, and the Cold War era country is retrospectively designated as the Bonn Republic. At the onset of the Cold War, Europe was divided between the Western and Eastern blocs. Germany was divided into the two countries. Initially, West Germany claimed an exclusive mandate for all of Germany, representing itself ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Jacques Dubochet D81 4477 (38005059805)
Ancient and noble French family names, Jacques, Jacq, or James are believed to originate from the Middle Ages in the historic northwest Brittany region in France, and have since spread around the world over the centuries. To date, there are over one hundred identified noble families related to the surname by the Nobility & Gentry of Great Britain & Ireland. Origins The origin of this surname ultimately originates from the Latin, Jacobus which belongs to an unknown progenitor. Jacobus comes from the Hebrew name, Yaakov, which translates as "one who follows" or "to follow after". Ancient history A French knight returning from the Crusades in the Holy Lands probably adopted the surname from "Saint Jacques" (or "James the Greater"). James the Greater was one of Jesus' Twelve Apostles, and is believed to be the first martyred apostle. Being endowed with this surname was an honor at the time and it is likely that the Church allowed it because of acts during the Crusades. Indeed, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Royal Photographic Society
The Royal Photographic Society of Great Britain, commonly known as the Royal Photographic Society (RPS), is one of the world's oldest photographic societies. It was founded in London, England, in 1853 as the Photographic Society of London with the objective of promoting the art and science of photography, and in 1853 received royal patronage from Queen Victoria and Prince Albert. A change to the society's name to reflect the patronage was, however, not considered expedient at the time. In 1874, it was renamed the Photographic Society of Great Britain, and only from 1894 did it become known as the Royal Photographic Society of Great Britain, a title which it continues to use today. On 25 June 2019, the Duchess of Cambridge, now Catherine, Princess of Wales, became the Society's Patron, taking over from Queen Elizabeth II who had been patron since 1952. A registered charity since 1962, in July 2004, the society was granted a royal charter recognising its eminence in the field of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national "newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |