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Intervertebral Disc Damage And Spaceflight
Astronauts have expressed an increased incidence of back pain during spaceflight and Spinal disc herniation, herniated intervertebral discs (IVD) have been diagnosed upon return of Skylab and Space Shuttle program, Shuttle spaceflight participants. These conditions and symptoms may be from previous back injury, but the evidence of IVD injuries raises the concern that astronauts are at an increased risk of intervertebral disc damage during loading scenarios experienced during exploration missions (re-entry to a gravitational field and activities on planetary surfaces). To date, flight data related to potential back injuries have focused on spine elongation and the well-established effects of mechanical unloading on intervertebral discs. Causes and current studies Sixty-eight percent of early astronauts, through 1991, who have flown in space have reported generalized back pain. The pain is considered most painful during early flight and lessens as the flight progresses. Possible cau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spaceflight
Spaceflight (or space flight) is an application of astronautics to fly spacecraft into or through outer space, either with or without humans on board. Most spaceflight is uncrewed and conducted mainly with spacecraft such as satellites in orbit around Earth, but also includes space probes for flights beyond Earth orbit. Such spaceflight operates either by telerobotic or autonomous control. The more complex human spaceflight has been pursued soon after the first orbital satellites and has reached the Moon and permanent human presence in space around Earth, particularly with the use of space stations. Human spaceflight programs include the Soyuz, Shenzhou, the past Apollo Moon landing and the Space Shuttle programs, with currently the International Space Station as the main destination of human spaceflight missions while China's Tiangong Space Station is under construction. Spaceflight is used for placing in Earth's orbit communications satellites, reconnaissance sat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Compressive Strength
In mechanics, compressive strength or compression strength is the capacity of a material or structure to withstand loads tending to reduce size (as opposed to tensile strength which withstands loads tending to elongate). In other words, compressive strength resists compression (being pushed together), whereas tensile strength resists tension (being pulled apart). In the study of strength of materials, tensile strength, compressive strength, and shear strength can be analyzed independently. Some materials fracture at their compressive strength limit; others deform irreversibly, so a given amount of deformation may be considered as the limit for compressive load. Compressive strength is a key value for design of structures. Compressive strength is often measured on a universal testing machine. Measurements of compressive strength are affected by the specific test method and conditions of measurement. Compressive strengths are usually reported in relationship to a specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lumbar Vertebrae
The lumbar vertebrae are, in human anatomy, the five vertebrae between the rib cage and the pelvis. They are the largest segments of the vertebral column and are characterized by the absence of the foramen transversarium within the transverse process (since it is only found in the cervical region) and by the absence of facets on the sides of the body (as found only in the thoracic region). They are designated L1 to L5, starting at the top. The lumbar vertebrae help support the weight of the body, and permit movement. Human anatomy General characteristics The adjacent figure depicts the general characteristics of the first through fourth lumbar vertebrae. The fifth vertebra contains certain peculiarities, which are detailed below. As with other vertebrae, each lumbar vertebra consists of a ''vertebral body'' and a ''vertebral arch''. The vertebral arch, consisting of a pair of ''pedicles'' and a pair of ''laminae'', encloses the ''vertebral foramen'' (opening) and s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cervical Vertebrae
In tetrapods, cervical vertebrae (singular: vertebra) are the vertebrae of the neck, immediately below the skull. Truncal vertebrae (divided into thoracic and lumbar vertebrae in mammals) lie caudal (toward the tail) of cervical vertebrae. In sauropsid species, the cervical vertebrae bear cervical ribs. In lizards and saurischian dinosaurs, the cervical ribs are large; in birds, they are small and completely fused to the vertebrae. The vertebral transverse processes of mammals are homologous to the cervical ribs of other amniotes. Most mammals have seven cervical vertebrae, with the only three known exceptions being the manatee with six, the two-toed sloth with five or six, and the three-toed sloth with nine. In humans, cervical vertebrae are the smallest of the true vertebrae and can be readily distinguished from those of the thoracic or lumbar regions by the presence of a foramen (hole) in each transverse process, through which the vertebral artery, vertebral veins, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weightlessness
Weightlessness is the complete or near-complete absence of the sensation of weight. It is also termed zero gravity, zero G-force, or zero-G. Weight is a measurement of the force on an object at rest in a relatively strong gravitational field (such as on the surface of the Earth). These weight-sensations originate from contact with supporting floors, seats, beds, scales, and the like. A sensation of weight is also produced, even when the gravitational field is zero, when contact forces act upon and overcome a body's inertia by mechanical, non- gravitational forces- such as in a centrifuge, a rotating space station, or within an accelerating vehicle. When the gravitational field is non-uniform, a body in free fall experiences tidal effects and is not stress-free. Near a black hole, such tidal effects can be very strong. In the case of the Earth, the effects are minor, especially on objects of relatively small dimensions (such as the human body or a spacecraft) and the overa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skylab 4
Skylab 4 (also SL-4 and SLM-3) was the third crewed Skylab mission and placed the third and final crew aboard the first American space station. The mission began on November 16, 1973, with the launch of Gerald P. Carr, Edward Gibson, and William R. Pogue in an Apollo command and service module on a Saturn IB rocket from the Kennedy Space Center, Florida, and lasted 84 days, one hour and 16 minutes. A total of 6,051 astronaut-utilization hours were tallied by the Skylab 4 astronauts performing scientific experiments in the areas of medical activities, solar observations, Earth resources, observation of the Comet Kohoutek and other experiments. The crewed Skylab missions were officially designated Skylab 2, 3, and 4. Miscommunication about the numbering resulted in the mission emblems reading "Skylab I", "Skylab II", and "Skylab 3" respectively. Launch NASA's launch center was located in an area called Cape Kennedy since May 15, 1964. Cape Kennedy was renamed Cape Canaveral off ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteoglycan
Proteoglycans are proteins that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein" with one or more covalently attached glycosaminoglycan (GAG) chain(s). The point of attachment is a serine (Ser) residue to which the glycosaminoglycan is joined through a tetrasaccharide bridge (e.g. chondroitin sulfate-GlcA- Gal-Gal- Xyl-PROTEIN). The Ser residue is generally in the sequence -Ser- Gly-X-Gly- (where X can be any amino acid residue but proline), although not every protein with this sequence has an attached glycosaminoglycan. The chains are long, linear carbohydrate polymers that are negatively charged under physiological conditions due to the occurrence of sulfate and uronic acid groups. Proteoglycans occur in connective tissue. Types Proteoglycans are categorized by their relative size (large and small) and the nature of their glycosaminoglycan chains. Types include: Certain members are considered members of the "small leucine-rich prote ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from computed tomography (CT) and positron emission tomography (PET) scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, although "open ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osmotic Pressure
Osmotic pressure is the minimum pressure which needs to be applied to a solution to prevent the inward flow of its pure solvent across a semipermeable membrane. It is also defined as the measure of the tendency of a solution to take in a pure solvent by osmosis. Potential osmotic pressure is the maximum osmotic pressure that could develop in a solution if it were separated from its pure solvent by a semipermeable membrane. Osmosis occurs when two solutions containing different concentrations of solute are separated by a selectively permeable membrane. Solvent molecules pass preferentially through the membrane from the low-concentration solution to the solution with higher solute concentration. The transfer of solvent molecules will continue until equilibrium is attained. Theory and measurement Jacobus van 't Hoff found a quantitative relationship between osmotic pressure and solute concentration, expressed in the following equation: :\Pi = icRT where \Pi is osmotic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinal Disc Herniation
Spinal disc herniation is an injury to the cushioning and connective tissue between vertebrae, usually caused by excessive strain or trauma to the spine. It may result in back pain, pain or sensation in different parts of the body, and physical disability. The most conclusive diagnostic tool for disc herniation is MRI, and treatment may range from painkillers to surgery. Protection from disc herniation is best provided by core strength and an awareness of body mechanics including posture. When a tear in the outer, fibrous ring of an intervertebral disc allows the soft, central portion to bulge out beyond the damaged outer rings, the disc is said to be herniated. Disc herniation is frequently associated with age-related degeneration of the outer ring, known as the '' annulus fibrosus'', but is normally triggered by trauma or straining by lifting or twisting. Tears are almost always posterolateral (on the back sides) owing to relative narrowness of the posterior longitudin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
G-force
The gravitational force equivalent, or, more commonly, g-force, is a measurement of the type of force per unit mass – typically acceleration – that causes a perception of weight, with a g-force of 1 g (not gram in mass measurement) equal to the conventional value of gravitational acceleration on Earth, ''g'', of about . Since g-forces indirectly produce weight, any g-force can be described as a "weight per unit mass" (see the synonym specific weight). When the g-force is produced by the surface of one object being pushed by the surface of another object, the reaction force to this push produces an equal and opposite weight for every unit of each object's mass. The types of forces involved are transmitted through objects by interior mechanical stresses. Gravitational acceleration (except certain electromagnetic force influences) is the cause of an object's acceleration in relation to free fall. The g-force experienced by an object is due to the vector sum o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleus Pulposus
An intervertebral disc (or intervertebral fibrocartilage) lies between adjacent vertebrae in the vertebral column. Each disc forms a fibrocartilaginous joint (a symphysis), to allow slight movement of the vertebrae, to act as a ligament to hold the vertebrae together, and to function as a shock absorber for the spine. Structure Intervertebral discs consist of an outer fibrous ring, the anulus fibrosus disci intervertebralis, which surrounds an inner gel-like center, the nucleus pulposus. The ''anulus fibrosus'' consists of several layers (laminae) of fibrocartilage made up of both type I and type II collagen. Type I is concentrated toward the edge of the ring, where it provides greater strength. The stiff laminae can withstand compressive forces. The fibrous intervertebral disc contains the ''nucleus pulposus'' and this helps to distribute pressure evenly across the disc. This prevents the development of stress concentrations which could cause damage to the underlying vertebra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
