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Institute Of Medical Science (Japan)
The Institute of Medical Science (Tōkyō-daigaku Ikagaku Kenkyūjo 東京大学医科学研究所) is an ancillary establishment of the University of Tokyo. It succeeded established in 1892 and is the foremost institute for medical and bioscience research in Japan. A research hospital is attached to the institute. The former Institute of Public Health was located on the site. History *1892: Dainihon Shiritu Eiseikai Fuzoku Densenbyo Kenkyujyo (Empire of Japan Private Sanitation Meeting Attachment Institute of Infectious Diseases) was established. *1899: It became the National Institute of Infectious Diseases under the jurisdiction of the Ministry of the Interior. *1914: The institute entered under the management of the Ministry of Education). *1916: It becomes an ancillary establishment of Tokyo Imperial University. *1967: Densenbyo Kenkyujyo (Institute of Infectious Diseases) was reorganized, then, Ikagaku Kenkyu-jyo (Institute of Medical Science) was established. Organiza ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yoshikazu Uchida
was a Japanese architect and structural engineer. He designed many buildings on the campus of the University of Tokyo, and served as the 14th president of the university. Career Uchida was one of five 1907 graduates from the Department of Architecture of Tokyo Imperial University. For the next four years he worked as an architect in the real estate division of the Mitsubishi group. In 1910, he returned to Tokyo Imperial University for graduate studies under Toshikata Sano, the country's leading structural engineer and a pioneer in the study of earthquake resistant architecture. From 1911, Uchida lectured at the university on structural engineering. As Sano's successor, he did pioneering work in the study of steel frame and reinforced concrete construction. He also made important contributions in the fields of fire prevention, urban planning, and the restoration of cultural monuments. His interests were wide-ranging, and he influenced nearly every aspect of architectural engineer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cord Blood Bank
A cord blood bank is a facility which stores umbilical cord blood for future use. Both private and public cord blood banks have developed in response to the potential for cord blood in treating diseases of the blood and immune systems. Public cord blood banks accept donations to be used for anyone in need, and as such function like public blood banks. Traditionally, public cord blood banking has been more widely accepted by the medical community. Private cord blood banks store cord blood solely for potential use by the donor or donor's family. Private banks typically charge around $2,000 for the collection and around $200 a year for storage. The policy of the American Academy of Pediatrics states that "private storage of cord blood as 'biological insurance' is unwise" unless there is a family member with a current or potential need to undergo a stem cell transplantation. The American Academy of Pediatrics also notes that the odds of using one's own cord blood is 1 in 200,000 while ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Science
Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for hea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amgen
Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical Corporation, company headquartered in Thousand Oaks, California. As one of the world's largest independent biotechnology companies, Amgen has approximately 24,000 staff in total as of 2022. The name "AMGen" is a portmanteau of the company's original name, Applied Molecular Genetics, which became the official name of the company in 1983 (three years after incorporation and coincident with its initial public offering). The company is listed on the Nasdaq Global Select Market under the ticker symbol "AMGN", as well as a component of the Nasdaq-100, the Dow Jones Industrial Average, and the S&P 100 and S&P 500, 500 indices. History Amgen was established in Thousand Oaks in 1980, as Applied Molecular Genetics.Baker, Pam (2002). ''Thousand Oaks Westlake Village: A Contemporary Portrait''. Community Communications, Inc., p. 37. . Amgen was backed by a small group of venture capital ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Minoru Kanehisa
(born January 23, 1948) is a Japanese bioinformatician. He is a project professor at Kyoto University, technical director of Pathway Solutions Inc and president of NPO Bioinformatics Japan. He is one of Japan's most recognized and respected bioinformatics experts and is known for developing the KEGG bioinformatics database. In 2018 he was listed on a list of Clarivate Citation Laureates for the Nobel Prize in Physiology or Medicine for "contributions to bioinformatics, specifically for his development of the Kyoto Encyclopedia of Genes and Genomes (KEGG)". Career Kanehisa studied at the University of Tokyo, gaining his Doctor of Science degree in physics in 1976. Following postdoctoral studies at Johns Hopkins School of Medicine and Los Alamos National Laboratory, he became a staff scientist at Los Alamos in 1981. While at Los Alamos, he was one of the developers of the GenBank database of all publicly available nucleotide sequences and their protein translations. Kanehisa joine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regulation Of Gene Expression
Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources. Virtually any step of gene expression can be modulated, from Transcriptional regulation, transcriptional initiation, to RNA processing, and to the post-translational modification of a protein. Often, one gene regulator controls another, and so on, in a gene regulatory network. Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. Although as early as 1951, Barbara McClintock showed interaction between two genetic loci, Activator (''Ac'') and Dissociator (''Ds''), in the color f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stem Cell Therapy
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. , the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood. Research is underway to develop various sources for stem cells as well as to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes and heart disease. Stem-cell therapy has become controversial following developments such as the ability of scientists to isolate and culture embryonic stem cells, to create stem cells using somatic cell nuclear transfer, and their use of techniques to create induced pluripotent stem cells. This controversy is often related to abortion politics and human cloning. Additionally, efforts to market treatments based on transplant of stored umbilical cord blood have been controversial. Medical us ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chihiro Sasakawa
is a Japanese bacteriologist well known for his pioneering research into the invasive mechanisms of pathogenic bacteria and the host’s subsequent immune response to infection. In his work on Shigella species and Helicobacter pylori, Sasakawa was an early adopter of a multi-disciplinary research strategy, combining molecular biology, cellular biology, biochemistry and immunological approaches. This research strategy and his discoveries greatly influenced later research on the invasive mechanisms of other pathogenic bacteria. Biography Sasakawa was born in 1948 in Tokyo. He graduated from the Faculty of Science at Chiba University in 1972, and obtained his doctorate from the Graduate school of Medicine, the University of Tokyo in 1978. Following research stints at the Institute of Medical Science, the University of Tokyo (1978-1980) and the Washington University School of Medicine as an NIH Fogarty Fellow (1980-1983), he became an associate professor at the Institute of Medical S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yoshihiro Kawaoka
is a virologist specializing in the study of the influenza and Ebola viruses. He holds a professorship in virology in the Department of Pathobiological Sciences at the University of Wisconsin-Madison, USA, and at the University of Tokyo, Japan. Following the West African Ebola virus epidemic of 2014, Kawaoka attempted to develop an Ebola vaccine working in close coordination with Alhaji N'jai a toxicologist at the University of Wisconsin–Madison and his non-profit organization Project 1808, Inc. Controversial experiment Kawaoka created a new virus based on H5N1, which he revealed to the public in 2011. For now, no known vaccine has been developed. His research was halted by a moratorium issued from the US government in 2014. However, in 2019 he was allowed to resume the research. Dan Brown mentioned the experiment in his novel '' Inferno''. Recognition *2006 – Robert Koch Prize (with Peter Palese) *2011 – Medal with Purple Ribbon *2013 – Members of the United Sta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virology
Virology is the Scientific method, scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host (biology), host cell (biology), cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. The identification of the causative agent of tobacco mosaic disease (TMV) as a novel pathogen by Martinus Beijerinck (1898) is now acknowledged as being the history of virology, official beginning of the field of virology as a discipline distinct from bacteriology. He realized the source was neither a bacterial nor a fungal infection, but something completely different. Beijerinck used the word "virus" to describe the mysterious agent in his 'contagium vivum fluidum' ('contagious living fluid'). Rosalind Franklin proposed the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mucosal Immunology
Mucosal immunology is the study of immune system responses that occur at mucosal membranes of the intestines, the urogenital tract, and the respiratory system. The mucous membranes are in constant contact with microorganisms, food, and inhaled antigens. In healthy states, the mucosal immune system protects the organism against infectious pathogens and maintains a tolerance towards non-harmful commensal microbes and benign environmental substances. Disruption of this balance between tolerance and deprivation of pathogens can lead to pathological conditions such as food allergies, irritable bowel syndrome, susceptibility to infections, and more. The mucosal immune system consists of a cellular component, humoral immunity, and defense mechanisms that prevent the invasion of microorganisms and harmful foreign substances into the body. These defense mechanisms can be divided into physical barriers ( epithelial lining, mucus, cilia function, intestinal peristalsis, etc.) and chemi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
