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Institute Of Chemical Biology And Fundamental Medicine
Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the RAS, ICBFM SB RAS (russian: link=no, Институт химической биологии и фундаментальной медицины СО РАН, ИХБФМ СО РАН) is a research institute in Novosibirsk, Russia. It was founded in 1984. History The Institute of Chemical Biology and Fundamental Medicine (formerly the Novosibirsk Institute of Bioorganic Chemistry) was founded on 1 April 1984. Scientific activity Creation of gene-targeted biological preparations, developments in the field of gene therapy, the study of physical and chemical processes of transmission and preservation of hereditary information. Test system for detection of SARS-CoV-2 Omicron variant At the end of 2021, the staff of the ICBFM SB RAS, together with scientists from Saint Petersburg, created a test system that simultaneously detects the presence of the genetic material of the coronavirus and determines wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Siberian Branch Of The Russian Academy Of Sciences
The Siberian Branch of the Russian Academy of Sciences (SBRAS) was established by the Decree of the Government of the USSR which was based on the proposal of Mikhail Lavrentyev, Sergei Sobolev and Sergey Khristianovich in 1957 as a regional division of the Academy of Sciences of the USSR, replacing a previous small branch of the Academy of Sciences of the USSR. Novosibirsk State University was founded to serve as a staff base for the Siberian Branch. Lavrentyev was also the founding chairman of the branch. Publications The Siberian branch publishes two journals — '' Archaeology, Ethnology & Anthropology of Eurasia'' and ''Geography and Natural Resource'' — in association with Elsevier Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as '' The Lancet'', '' Cell'', the ScienceDirect collection of electronic journals, '' Trends'', .... References 1957 establishments i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novosibirsk
Novosibirsk (, also ; rus, Новосиби́рск, p=nəvəsʲɪˈbʲirsk, a=ru-Новосибирск.ogg) is the largest city and administrative centre of Novosibirsk Oblast and Siberian Federal District in Russia. As of the 2021 Census, it had a population of 1,633,595, making it the most populous city in Siberia and the third-most populous city in Russia. The city is located in southwestern Siberia, on the banks of the Ob River. Novosibirsk was founded in 1893 on the Ob River crossing point of the future Trans-Siberian Railway, where the Novosibirsk Rail Bridge was constructed. Originally named Novonikolayevsk ("New Nicholas") in honor of Emperor Nicholas II, the city rapidly grew into a major transport, commercial, and industrial hub. Novosibirsk was ravaged by the Russian Civil War but recovered during the early Soviet period and gained its present name, Novosibirsk ("New Siberia"), in 1926. Under the leadership of Joseph Stalin, Novosibirsk became one of the large ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academician Lavrentyev Avenue, Novosibirsk
Academician Lavrentyev Avenue (russian: Проспект Лаврентьева) or Academician Lavrentyev Prospekt is a street in Akademgorodok of Novosibirsk, Russia. The avenue is named after Mikhail Lavrentyev, a Soviet mathematician and hydrodynamicist. Research institutes * Institute of Cytology and Genetics * Nikolaev Institute of Inorganic Chemistry * Rzhanov Institute of Semiconductor Physics * Institute of Soil Science and Agrochemistry * Lavrentyev Institute of Hydrodynamics * Institute of Chemical Biology and Fundamental Medicine * Budker Institute of Nuclear Physics * Institute of Laser Physics * Boreskov Institute of Catalysis * Institute of Computational Technologies * Ershov Institute of Informatics Systems * Institute of Computational Mathematics and Mathematical Geophysics * Kutateladze Institute of Thermophysics * Institute of Economics and Industrial Engineering * Vorozhtsov Novosibirsk Institute of Organic Chemistry * Institute of Archaeology and Et ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Targeting
Gene targeting (also, replacement strategy based on homologous recombination) is a genetic technique that uses homologous recombination to modify an endogenous gene. The method can be used to delete a gene, remove exons, add a gene and modify individual base pairs (introduce point mutations). The process of gene targeting provides a way to alter specific genes in order to better identify their biological roles. Gene targeting can be permanent or conditional. Conditions can be a specific time during development / life of the organism or limitation to a specific tissue, for example. Gene targeting requires the creation of a specific vector for each gene of interest. However, it can be used for any gene, regardless of transcriptional activity or gene size. Methods In general, DNA containing part of the gene to be targeted, a reporter gene, and a (dominant) selectable marker is assembled in bacteria. Gene targeting methods are established for several model organisms and may v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Therapy
Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DNA was performed in 1980, by Martin Cline, but the first successful nuclear gene transfer in humans, approved by the National Institutes of Health, was performed in May 1989. The first therapeutic use of gene transfer as well as the first direct insertion of human DNA into the nuclear genome was performed by French Anderson in a trial starting in September 1990. It is thought to be able to cure many genetic disorders or treat them over time. Between 1989 and December 2018, over 2,900 clinical trials were conducted, with more than half of them in phase I.Gene Therapy Cl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saint Petersburg
Saint Petersburg ( rus, links=no, Санкт-Петербург, a=Ru-Sankt Peterburg Leningrad Petrograd Piter.ogg, r=Sankt-Peterburg, p=ˈsankt pʲɪtʲɪrˈburk), formerly known as Petrograd (1914–1924) and later Leningrad (1924–1991), is the List of cities and towns in Russia by population, second-largest city in Russia. It is situated on the Neva River, at the head of the Gulf of Finland on the Baltic Sea, with a population of roughly 5.4 million residents. Saint Petersburg is the List of European cities by population within city limits, fourth-most populous city in Europe after Istanbul, Moscow and London, the List of cities and towns around the Baltic Sea, most populous city on the Baltic Sea, and the world's List of northernmost items#Cities and settlements, northernmost city of more than 1 million residents. As Russia's Imperial capital, and a Ports of the Baltic Sea, historically strategic port, it is governed as a Federal cities of Russia, federal city. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SARS-CoV-2 Omicron Variant
Omicron (B.1.1.529) is a variant of SARS-CoV-2 first reported to the World Health Organization (WHO) by the Network for Genomics Surveillance in South Africa on 24 November 2021. It was first detected in Botswana and has spread to become the predominant variant in circulation around the world. Following the original BA.1 variant, several subvariants of Omicron have emerged: BA.2, BA.3, BA.4, and BA.5. Since October 2022, two subvariants of BA.5 named BQ.1 and BQ.1.1 have spread rapidly. Three doses of a COVID-19 vaccine provide protection against severe disease and hospitalisation caused by BA.1 and BA.2. The immunity effects of BA.2 are similar to those of BA.1. For three-dose vaccinated individuals, the BA.4 and BA.5 variants are more infectious than previous subvariants, making it likely, , for a new peak in COVID-19 infections to occur. __TOC__ Classification On 26 November, the WHO's Technical Advisory Group on SARS-CoV-2 Virus Evolution declared PANGO lineage ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jennifer Doudna
Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing." She is the Li Ka Shing Chancellor's Chair Professor in the Department of Chemistry and the Department of Molecular and Cell Biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997. She graduated from Pomona College in 1985 and earned a Ph.D. from Harvard Medical School in 1989. Apart from her professorship at Berkeley, she is also president and chair of the board of the Innovative Genomics Institute, a faculty scientist at Lawrence Berkeley National Laboratory, a senior investigator at the Gladstone Institutes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emmanuelle Charpentier
Emmanuelle Marie Charpentier (; born 11 December 1968) is a French professor and researcher in microbiology, genetics, and biochemistry. As of 2015, she has been a director at the Max Planck Institute for Infection Biology in Berlin. In 2018, she founded an independent research institute, the Max Planck Unit for the Science of Pathogens. In 2020, Charpentier and American biochemist Jennifer Doudna of the University of California, Berkeley, were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing" (through CRISPR). This was the first science Nobel Prize ever won by two women only. Early life and education Born in 1968 in Juvisy-sur-Orge in France, Charpentier studied biochemistry, microbiology, and genetics at the Pierre and Marie Curie University (today the Faculty of Science of Sorbonne University) in Paris. She was a graduate student at the Institut Pasteur from 1992 to 1995 and was awarded a research doctorate. Charpentier's PhD ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Institutes In Novosibirsk
Research is "creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, economic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1984 Establishments In The Soviet Union
Events January * January 1 – The Bornean Sultanate of Brunei gains full independence from the United Kingdom, having become a British protectorate in 1888. * January 7 – Brunei becomes the sixth member of the Association of Southeast Asian Nations (ASEAN). * January 10 ** The United States and the Vatican City, Vatican (Holy See) restore full diplomatic relations. ** The Victoria, Seychelles, Victoria Agreement is signed, institutionalising the Indian Ocean Commission. *January 24 – Steve Jobs launches the Macintosh 128K, Macintosh personal computer in the United States. February * February 3 ** Dr. John Buster and the research team at Harbor–UCLA Medical Center announce history's first embryo transfer from one woman to another, resulting in a live birth. ** STS-41-B: Space Shuttle Challenger, Space Shuttle ''Challenger'' is launched on the 10th Space Shuttle mission. * February 7 – Astronauts Bruce McCandless II and Robert L. Stewart make the first untethered spac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Institutes Established In 1984
Research is "creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, economic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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