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ImClone Systems
ImClone Systems LLC was a biopharmaceutical company dedicated to developing biologic medicines in the area of oncology. It was founded in 1984 and had its corporate headquarters in Bridgewater, New Jersey, and its research headquarters in New York City. On October 6, 2008, it accepted a $6.5 billion acquisition offer from Eli Lilly and Company, and became a fully-owned subsidiary of Eli Lilly and Company on November 24, 2008. Prior to the acquisition, it was traded on the NASDAQ stock exchange under the symbol IMCL. Imclone lost its separate identity in 2014 when its former ImClone research and manufacturing sites were renamed as ''Eli Lilly and Company''. Insider trading scandal ImClone's stock price dropped sharply at the end of 2001 when its drug Erbitux, an experimental monoclonal antibody, failed to get the expected Food and Drug Administration (FDA) approval. It was later revealed by the U.S. Securities and Exchange Commission that numerous executives sold their stock be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subsidiary
A subsidiary, subsidiary company, or daughter company is a company (law), company completely or partially owned or controlled by another company, called the parent company or holding company, which has legal and financial control over the subsidiary company. Unlike regional branches or divisions, subsidiaries are considered to be distinct entities from their parent companies; they are required to follow the laws of where they are incorporated, and they maintain their own executive leadership. Two or more subsidiaries primarily controlled by same entity/group are considered to be sister companies of each other. Subsidiaries are a common feature of modern business, and most multinational corporations organize their operations via the creation and purchase of subsidiary companies. Examples of holding companies are Berkshire Hathaway, Jefferies Financial Group, The Walt Disney Company, Warner Bros. Discovery, and Citigroup, which have subsidiaries involved in many different Industry (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Martha Stewart Living Omnimedia
Martha Stewart Living Omnimedia Inc. (MSLO) is an American diversified media and merchandising company founded by Martha Stewart in 1997 and owned by Marquee Brands LLC since April 2019. It is organized into four business segments: publishing, Internet, broadcasting media platforms, and merchandising product lines. MSLO's business holdings include a variety of print publications, television and radio programming, and e-commerce websites. History The company was founded in 1997 by Martha Stewart as an umbrella company for the various media and merchandising ventures linked to the Martha Stewart brand. It went public, via an initial public offering, on the New York Stock Exchange (NYSE) on October 19, 1999. The stock opened at US$18 a share, but shot up to $38 a share, making Stewart an instant billionaire. On August 6, 2002, a class-action lawsuit was filed against the company for misleading investors by issuing materially false and misleading statements, and its officers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidermal Growth Factor Receptor
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor (biochemistry), receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligand (biochemistry), ligands. The epidermal growth factor receptor is a member of the ErbB, ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), ERBB3, Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer. Epidermal growth factor and its receptor was discovered by Stanley Cohen (biochemist), Stanley Cohen of Vanderbilt University. Cohen shared the 1986 Nobel Prize in Medicine with Rita Levi-Montalcini for their discovery of growth factors. Deficient signaling of the EGFR and other receptor tyrosine kinases in humans is associated with diseases such as Alzheimer's, while over-expression is associated with th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weizmann Institute Of Science
The Weizmann Institute of Science ( ''Machon Weizmann LeMada'') is a Public university, public research university in Rehovot, Israel, established in 1934, fourteen years before the State of Israel was founded. Unlike other List of Israeli universities and colleges, Israeli universities it exclusively offers postgraduate-only degrees in the natural science, natural and exact sciences. The institute is a multidisciplinary research center, employing around 3,800 scientists, Postdoctoral researcher, postdoctoral fellows, Ph.D. and M.Sc. students, and scientific, technical, and administrative staff working at the institute. As of 2019, the Weizmann Institute of Science has been associated with six Nobel laureates and three Turing Award winners. The Weizmann Institute of Science and Elbit Systems have collaborated on various projects, notably including the development and supply of the space telescope for Israel's Ultraviolet Transient Astronomy Satellite (ULTRASAT) program and re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carl Icahn
Carl Celian Icahn (; born February 16, 1936) is an American businessman and investor. He is the founder and controlling shareholder of Icahn Enterprises, a public company and diversified conglomerate holding company based in Sunny Isles Beach, Sunny Isles Beach, Florida. Icahn's business model is to take large stakes in companies that he believes will appreciate from changes to corporate policy; Icahn then pressures management to make the changes that he believes will benefit shareholders, and him. Widely regarded as one of the most successful hedge fund managers of all time and one of the greatest investors on Wall Street, he was one of the first activist shareholders and is credited with making that investment strategy mainstream for hedge funds. In the 1980s, Icahn developed a reputation as a "corporate raider" after profiting from the hostile takeover and asset stripping of Trans World Airlines. Icahn is on the Forbes 400, ''Forbes'' 400 and has a net worth of approximately ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Boston Globe
''The Boston Globe,'' also known locally as ''the Globe'', is an American daily newspaper founded and based in Boston, Massachusetts. The newspaper has won a total of 27 Pulitzer Prizes. ''The Boston Globe'' is the oldest and largest daily newspaper in Boston and tenth-largest newspaper by print circulation in the nation as of 2023. Founded in 1872, the paper was mainly controlled by Irish Catholic interests before being sold to Charles H. Taylor and his family. After being privately held until 1973, it was sold to ''The New York Times'' in 1993 for $1.1billion, making it one of the most expensive print purchases in United States history. The newspaper was purchased in 2013 by Boston Red Sox and Liverpool F.C. owner John W. Henry for $70million from The New York Times Company, having lost over 90% of its value in 20 years. The chief print rival of ''The Boston Globe'' is the '' Boston Herald'', whose circulation is smaller and is shrinking faster. The newspaper is "one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
WebMD
WebMD is an American corporation which publishes online news and information about human health and well-being. The WebMD website also includes information about drugs and is an important healthcare information website and the most popular consumer-oriented health site. WebMD was started in 1998 by internet entrepreneur Jeff Arnold. In early 1999, it was part of a three-way merger with Sapient Health Network (SHN) and Direct Medical Knowledge (DMK). SHN began in Portland, Oregon, in 1996 by Jim Kean, Bill Kelly, and Kris Nybakken, who worked together at a CD-ROM publishing firm, Creative Multimedia. Later, in 1999, WebMD merged with Healtheon, founded by Netscape Communications founder James H. Clark. History WebMD is best known as a health information services website, which publishes content regarding health and health care topics, including a symptom checklist, pharmacy information, drugs information, and blogs of physicians with specific topics, and provides a place t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
60 Minutes
''60 Minutes'' is an American television news magazine broadcast on the CBS television network. Debuting in 1968, the program was created by Don Hewitt and Bill Leonard, who distinguished it from other news programs by using a unique style of reporter-centered investigation. In 2002, ''60 Minutes'' was ranked number six on ''TV Guide''s list of the " 50 Greatest TV Shows of All Time", and in 2013, it was ranked number 24 on the magazine's list of the "60 Best Series of All Time". In 2023, '' Variety'' ranked ''60 Minutes'' as the twentieth-greatest TV show of all time. ''The New York Times'' has called it "one of the most esteemed news magazines on American television". The program began in 1968 as a bi-weekly television show hosted by Mike Wallace and Harry Reasoner. The two sat on opposite sides of the cream-colored set, though the set's color was later changed to black, the color still in use. The show used a large stopwatch during transition periods and highlighted its ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Expanded Access
Expanded access or compassionate use is the use of an unapproved drug or medical device under special forms of investigational new drug, investigational new drug applications (IND) or Investigational device exemption, IDE application for devices, outside of a clinical trial, by people with serious or life-threatening conditions who do not meet the enrollment criteria for the clinical trial in progress. These programs go under various names, including early access, special access, or managed access program, compassionate use, compassionate access, named-patient access, temporary authorization for use, cohort access, and pre-approval access. In general the person and their doctor must apply for access to the investigational product, the company has to choose to cooperate, and the medicine's regulatory agency needs to agree that the risks and possible benefits of the drug or device are understood well enough to determine if putting the person at risk has sufficient potential benefit. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Wall Street Journal
''The Wall Street Journal'' (''WSJ''), also referred to simply as the ''Journal,'' is an American newspaper based in New York City. The newspaper provides extensive coverage of news, especially business and finance. It operates on a subscription model, requiring readers to pay for access to most of its articles and content. The ''Journal'' is published six days a week by Dow Jones & Company, a division of News Corp. As of 2023, ''The'' ''Wall Street Journal'' is the List of newspapers in the United States, largest newspaper in the United States by print circulation, with 609,650 print subscribers. It has 3.17 million digital subscribers, the second-most in the nation after ''The New York Times''. The newspaper is one of the United States' Newspaper of record, newspapers of record. The first issue of the newspaper was published on July 8, 1889. The Editorial board at The Wall Street Journal, editorial page of the ''Journal'' is typically center-right in its positio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bristol-Myers Squibb
The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company. Headquartered in Princeton, New Jersey, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the largest U.S. corporations. For fiscal 2022, it had a total revenue of $46.2 billion. Bristol Myers Squibb manufactures prescription pharmaceuticals and biologics in several therapeutic areas, including cancer, HIV/AIDS, cardiovascular disease, diabetes, hepatitis, rheumatoid arthritis, and psychiatric disorders. BMS's primary research and development (R&D) sites are located in Lawrence, New Jersey (formerly Squibb, near Princeton), Summit, New Jersey, formerly HQ of Celgene, New Brunswick, New Jersey; Redwood City, California; and Seville in Spain, with other sites in Devens and Cambridge, Massachusetts; Braine-l'Alleud, Belgium; Tokyo, Japan; Hyderabad; Bangalore, India and Wirr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
