Hypersensitivity (other)
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Hypersensitivity (other)
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an undesirable and adverse immune response to an antigen. Hypersensitivity or hypersensitive may also refer to: *Hypersensitivity, or Sensory Processing Sensitivity, a psychological condition relating to sensitivity to processing information. * Hypersensitization, a cellular increase in the expression of a specific receptor *Dentin hypersensitivity, a cause of dental pain *Hyperesthesia, abnormal increase in sensitivity to stimuli of the senses *Electromagnetic hypersensitivity *''Hypersensitive'', a music album *Hypersensitive response, infection defense in plants *Hypersensitive site, a region in chromatin *Sensory overload, experiencing overstimulation *Sensory processing disorder (SPD), a medical condition relating to abnormal multisensory integration Multisensory integration, also known as multimodal integration, is the study of how information from the different sensory modality, sensory modalities (su ...
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Hypersensitivity
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to an antigen. It is an abnormality in the immune system that causes Immune disorder, immune diseases including allergies and autoimmunity. It is caused by many types of particles and substances from the external environment or from within the body that are recognized by the immune cells as antigens. The immune reactions are usually referred to as an over-reaction of the immune system and they are often damaging and uncomfortable. In 1963, Philip George Houthem Gell and Robin Coombs introduced a systematic classification of the different types of hypersensitivity based on the types of antigens and immune responses involved. According to this system, known as the #Gell and Coombs classification, Gell and Coombs classification or Gell-Coombs's classification, there are four types of hypersensitivity, namely: Typ ...
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Sensory Processing Sensitivity
Sensory processing sensitivity (SPS) is a temperamental or personality trait involving "an increased sensitivity of the central nervous system and a deeper cognitive processing of physical, social, and emotional stimuli". The trait is characterized by "a tendency to 'pause to check' in novel situations, greater sensitivity to subtle stimuli, and the engagement of deeper cognitive processing strategies for employing coping actions, all of which is driven by heightened emotional reactivity, both positive and negative". A human with a particularly high measure of SPS is considered to have "hypersensitivity", or be a highly sensitive person (HSP). The terms ''SPS'' and ''HSP'' were coined in the mid-1990s by psychologists Elaine Aron and her husband Arthur Aron, who developed the Highly Sensitive Person Scale (HSPS) questionnaire by which SPS is measured. Other researchers have applied various other terms to denote this responsiveness to stimuli that is seen in humans and other ...
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Upregulation
In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by which a cell decreases the production and quantities of its cellular components, such as RNA and proteins, in response to an external stimulus. The complementary process that involves increase in quantities of cellular components is called upregulation. An example of downregulation is the cellular decrease in the expression of a specific receptor in response to its increased activation by a molecule, such as a hormone or neurotransmitter, which reduces the cell's sensitivity to the molecule. This is an example of a locally acting (negative feedback) mechanism. An example of upregulation is the response of liver cells exposed to such xenobiotic molecules as dioxin. In this situation, the cells increase their production of cytochrome P450 enzymes, which in turn increases degradation of these dioxin molecules. Downregulation ...
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Dentin Hypersensitivity
Dentin hypersensitivity (DH, DHS) is dental pain which is sharp in character and of short duration, arising from exposed dentin surfaces in response to stimuli, typically thermal, evaporative, tactile, osmosis, osmotic, chemical or electrical; and which cannot be ascribed to any other dental disease. A degree of dentin sensitivity is normal, but pain is not usually experienced in everyday activities like drinking a cooled drink. Therefore, although the terms ''dentin sensitivity'' and ''sensitive dentin'' are used interchangeably to refer to dental hypersensitivity, the latter term is the more accurate. Signs and symptoms The pain is sharp and sudden, in response to an external stimulus. The most common trigger is cold, with 75% of people with hypersensitivity reporting pain upon application of a cold stimulus. Other types of stimuli may also trigger pain in dentin hypersensitivity, including: * Thermal – hot and cold drinks and foods, cold air, coolant water jet from a dental ...
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Hyperesthesia
Hyperesthesia is a condition that involves an abnormal increase in sensitivity to stimuli of the senses. Stimuli of the senses can include sound that one hears, foods that one tastes, textures that one feels, and so forth. Increased touch sensitivity is referred to as "tactile hyperesthesia", and increased sound sensitivity is called "auditory hyperesthesia". In the context of pain, hyperaesthesia can refer to an increase in sensitivity where there is both allodynia and hyperalgesia. In psychology, Jeanne Siaud-Facchin uses the term by defining it as an "exacerbation des sens" that characterizes gifted individuals: for them, the sensory information reaches the brain much faster than the average, and the information is processed in a significantly shorter time. Other animals Feline hyperesthesia syndrome is an uncommon but recognized condition in cats, particularly Siamese, Burmese, Himalayan, and Abyssinian cats. It can affect cats of all ages, though it is most preval ...
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Electromagnetic Hypersensitivity
Electromagnetic hypersensitivity (EHS) is a claimed sensitivity to electromagnetic fields, to which adverse symptoms are attributed. EHS has no scientific basis and is not a recognized medical diagnosis, although it is generally accepted that the experience of EHS symptoms is of psychosomatic origin. Claims are characterized by a "variety of non-specific symptoms, which afflicted individuals attribute to exposure to electromagnetic fields". Attempts to justify the claim that EHS is caused by exposure to electromagnetic fields have amounted to pseudoscience. Those self-diagnosed with EHS report adverse reactions to electromagnetic fields at intensities well below the maximum levels permitted by international radiation safety standards. Provocation trials have found that such claimants are unable to distinguish between exposure and non-exposure to electromagnetic fields. A systematic review of medical research in 2011 found no convincing scientific evidence for symptoms bein ...
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Hypersensitive
''Hypersensitive'' is the second album by American rock band Ghost Machine. It was released on November 21, 2006, via Corporate Punishment Records. The original track listing of the album, displayed on sites like Amazon and AllMusic AllMusic (previously known as All-Music Guide and AMG) is an American online database, online music database. It catalogs more than three million album entries and 30 million tracks, as well as information on Musical artist, musicians and Mus ..., was identical to that of their self-titled debut album '' Ghost Machine'' (2005). However, it actually features ten new tracks and the older tracks have been slightly reworked. Track listing # "The End" – 2:12 # "Sheltered" – 4:00 # "Headstone" – 3:50 # "D.U.A." – 2:08 # "God Forbid" – 3:43 # "What You Made Me (Ugli)" – 3:21 # "Skank" – 3:35 # "Bondage" – 3:30 # "Vegas Moon" – 3:50 # "Desert Rose" – 4:32 # "Interlude" – 1:20 # "Crawl" – 4:14 # "Siesta Loca" – 4:00 # "E ...
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Hypersensitive Response
In Plant disease resistance, plant immunology, the hypersensitive response (HR) is a mechanism used by plants to prevent the spread of infection by microbial pathogens. HR is characterized by the rapid apoptosis, death of cells in the local region surrounding an infection and it serves to restrict the growth and spread of pathogens to other parts of the plant. It is analogous to the innate immune system found in animals, and commonly precedes a slower systemic (whole plant) response, which ultimately leads to systemic acquired resistance (SAR). HR can be observed in the vast majority of plant species and is induced by a wide range of plant pathogens such as oomycetes, viruses, fungi and even insects. HR is commonly thought of as an effective defence strategy against biotrophic plant pathogens, which require living tissue to gain nutrients. In the case of necrotrophic pathogens, HR might even be beneficial to the pathogen, as they require dead plant cells to obtain nutrients. Th ...
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Hypersensitive Site
In genetics, a hypersensitive site is a short region of chromatin and is detected by its super sensitivity to cleavage by DNase I and other various nucleases (DNase II and micrococcal nucleases). In a hypersensitive site, the nucleosomal structure is less compacted, increasing the availability of the DNA to binding by proteins, such as transcription factors and DNase I. These sites account for many inherited tendencies. Location Hypersensitive sites are found on every active gene, and many of these genes often have more than one hypersensitive site. Most often, hypersensitive sites are found only in chromatin of cells in which the associated gene is being expressed, and do not occur when the gene is inactive. In DNA being transcribed, 5'hypersensitive sites appear before transcription begins, and the DNA sequences within the hypersensitive sites are required for gene expression. Note: hypersensitive sites precede active promoters. Hypersensitive sites are generated as a r ...
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Sensory Overload
Sensory overload occurs when one or more of the body's senses experiences over-stimulation from the environment. There are many environmental elements that affect an individual. Examples of these elements are urbanization, crowding, noise, mass media, and technology. Signs and symptoms There are a wide variety of symptoms that have been found to be associated with sensory overload. These symptoms can occur in both children and adults. Some of these symptoms are: * Irritability * "Shutting down," or refusing to participate in activities and interact with others * Over-sensitivity to touch, movement, sights, or sounds ** Avoiding touching or being touched ** Irritation caused by shoes, socks, tags, or different textures ** Complaining about noises that do not affect others ** Covering eyes around bright lights ** Covering ears to close out sounds or voices * Excitability * Making poor eye contact * Constantly changing activities without completing any tasks * Having trouble wi ...
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Sensory Processing Disorder
Sensory processing disorder (SPD), formerly known as sensory integration dysfunction, is a condition in which multisensory input is not adequately processed in order to provide appropriate responses to the demands of the environment. Sensory processing disorder is present in many people with dyspraxia, autism spectrum disorder, and attention deficit hyperactivity disorder (ADHD). Individuals with SPD may inadequately process visual, auditory, olfactory (smell), gustatory (taste), tactile (touch), vestibular (balance), proprioception (body awareness), and interoception (internal body senses) sensory stimuli. Sensory integration was defined by occupational therapist Anna Jean Ayres in 1972 as "the neurological process that organizes sensation from one's own body and from the environment and makes it possible to use the body effectively within the environment". Sensory processing disorder has been characterized as the source of significant problems in organizing sensat ...
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Multisensory Integration
Multisensory integration, also known as multimodal integration, is the study of how information from the different sensory modality, sensory modalities (such as sight, sound, touch, smell, self-motion, and taste) may be integrated by the nervous system. A coherent representation of objects combining modalities enables animals to have meaningful perceptual experiences. Indeed, multisensory integration is central to adaptive behavior because it allows animals to perceive a world of coherent perceptual entities. Multisensory integration also deals with how different sensory modalities interact with one another and alter each other's processing. General introduction Multimodal perception is how animals form coherent, valid, and robust perception by sensory processing, processing sensory stimuli from various modalities. Surrounded by multiple objects and receiving multiple sensory stimulations, the brain is faced with the decision of how to categorize the stimuli resulting from different ...
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