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Human Betaherpesvirus 7
Human herpesvirus 7 (HHV-7) is one of nine known members of the ''Herpesviridae'' family that infects humans. HHV-7 is a member of ''Betaherpesvirinae'', a subfamily of the ''Herpesviridae'' that also includes HHV-6 and ''Cytomegalovirus'' (HHV-5 or HCMV). HHV-7 often acts together with HHV-6, and the viruses together are sometimes referred to by their genus, '' Roseolovirus''. HHV-7 was first isolated in 1990 from CD4+ T cells taken from peripheral blood lymphocytes. Signs and symptoms Both HHV-6B and HHV-7, as well as other viruses, can cause a skin condition in infants known as exanthema subitum, although HHV-7 causes the disease less frequently than HHV-6B. HHV-7 infection also leads to or is associated with a number of other symptoms, including acute febrile respiratory disease, fever, rash, vomiting, diarrhea, low lymphocyte counts, and febrile seizures, though most often no symptoms present at all. There are indications that HHV-7 can contribute to the development o ...
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Infectious Disease (medical Speciality)
Infectious diseases (ID), also known as infectiology, is a medical specialty dealing with the diagnosis and treatment of infections. An infectious diseases specialist's practice consists of managing nosocomial ( healthcare-acquired) infections or community-acquired infections. An ID specialist investigates and determines the cause of a disease (bacteria, virus, parasite, fungus or prions). Once the cause is known, an ID specialist can then run various tests to determine the best drug to treat the disease. While infectious diseases have always been around, the infectious disease specialty did not exist until the late 1900s after scientists and physicians in the 19th century paved the way with research on the sources of infectious disease and the development of vaccines. Scope Infectious diseases specialists typically serve as consultants to other physicians in cases of complex infections, and often manage patients with HIV/AIDS and other forms of immunodeficiency. Although many co ...
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Archives Of Disease In Childhood
''Archives of Disease in Childhood'' is a peer review, peer-reviewed medical journal published by the BMJ Group and covering the field of paediatrics. It is the official journal of the Royal College of Paediatrics and Child Health. Scope ''Archives of Disease in Childhood'' focuses on all aspects of pediatric nursing, child health and child disease, disease from the perinatal period through to adolescence. It includes original research reports, commentaries, reviews of clinical and policy issues, and evidence reports. Other sections include: guidelines updates, international health, and a column written by patients about their experience with the health care system. Douglas Gairdner served as editor from 1964 to 1979 and because of his creative editing, he was awarded the Dawson-Williams prize of the British Medical Association. Abstracting and indexing The journal is indexed on MEDLINE/Index Medicus, Web of Science, and EMBASE, Excerpta Medica. According to the ''Journal Cit ...
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Lichen Planus
Lichen planus (LP) is a chronic inflammatory and autoimmune disease that affects the skin, nails, hair, and mucous membranes. It is not an actual lichen, but is named for its appearance. It is characterized by polygonal, flat-topped, violaceous papules and plaques with overlying, reticulated, fine white scale (Wickham striae, Wickham's striae), commonly affecting dorsal hands, flexural wrists and forearms, trunk, anterior lower legs and oral mucosa. The hue may be gray-brown in people with darker skin. Although there is a broad clinical range of LP manifestations, the skin and oral cavity remain as the major sites of involvement. The cause is unknown, but it is thought to be the result of an autoimmune process with an unknown initial trigger. There is no cure, but many different medications and procedures have been used in efforts to control the symptoms. The term lichenoid reaction (lichenoid eruption or lichenoid lesion) refers to a lesion of similar or identical histopathology, ...
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Mononucleosis
Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). Most people are infected by the virus as children, when the disease produces few or no symptoms. In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and fatigue. Most people recover in two to four weeks; however, feeling tired may last for months. The liver or spleen may also become swollen, and in less than one percent of cases splenic rupture may occur. While usually caused by the Epstein–Barr virus, also known as human herpesvirus 4, which is a member of the herpesvirus family, a few other viruses and the protozoon ''Toxoplasma gondii'' may also cause the disease. It is primarily spread through saliva but can rarely be spread through semen or blood. Spread may occur by objects such as drinking glasses or toothbrushes or through a cough or sneeze. Those who are infected can spread the diseas ...
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Epstein–Barr Virus
The Epstein–Barr virus (EBV), also known as human herpesvirus 4 (HHV-4), is one of the nine known Herpesviridae#Human herpesvirus types, human herpesvirus types in the Herpesviridae, herpes family, and is one of the most common viruses in humans. EBV is a DNA virus#Double-stranded DNA viruses, double-stranded DNA virus. EBV is the first identified oncogenic virus, a virus that can cause cancer. EBV establishes permanent infection in human B cells. It uncommonly causes infectious mononucleosis and is also tightly linked to many Malignancy, malignant diseases (cancers and autoimmune diseases). Various vaccine formulations have been tested in animals and humans; however, none of them were able to prevent EBV infection, thus, no vaccine has been approved to date. Infectious mononucleosis ("mono" or "glandular fever"), is characterized by extreme fatigue, fever, sore throat, and swollen lymph nodes. EBV is also associated with various non-malignant, premalignant, and malignant E ...
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Pityriasis Rosea
Pityriasis rosea is a type of skin rash. Classically, it begins with a single red and slightly scaly area known as a "herald patch". This is then followed, days to weeks later, by an eruption of many smaller scaly spots; pinkish with a red edge in people with light skin and greyish in darker skin. About 20% of cases show atypical deviations from this pattern. It usually lasts less than three months and goes away without treatment. Sometimes malaise or a fever may occur before the start of the rash or itchiness, but often there are few other symptoms. While the cause is not entirely clear, it is believed to be related to human herpesvirus 6 (HHV6) or human herpesvirus 7 (HHV7). It does not appear to be contagious disease, contagious. Certain medications may result in a similar rash. Diagnosis is based on the symptoms. Evidence for specific treatment is limited. About 1.3% of people are affected at some point in time. It most often occurs in those between the ages of 10 and 35. ...
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Archives Of Neurology
''JAMA Neurology'' is a monthly peer-reviewed medical journal published by the American Medical Association. It was established in 1960 as ''Archives of Neurology'' and obtained its current name in 2013. The journal publishes research on the nervous system as well as the various mechanisms of neurological disease. Its editor-in-chief is S. Andrew Josephson. Naming History Abstracting and indexing The journal is abstracted and indexed in Index Medicus/MEDLINE/PubMed. According to ''Journal Citation Reports'', the journal's 2021 impact factor is 29.907, ranking it 3rd out of 212 titles in the category "Clinical Neurology". See also *List of American Medical Association journals There are thirteen medical journals published by the JAMA Network, a division of the American Medical Association (AMA). The ''Journal of the American Medical Association (JAMA)'', along with ''JAMA Network Open'' and eleven specialty journals, co ... References External links * Neurology journal ...
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Hepatitis
Hepatitis is inflammation of the liver parenchyma, liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), Anorexia (symptom), poor appetite, vomiting, fatigue (medicine), tiredness, abdominal pain, and diarrhea. Hepatitis is ''acute (medicine), acute'' if it resolves within six months, and ''chronic condition, chronic'' if it lasts longer than six months. Acute hepatitis can self-limiting (biology), resolve on its own, progress to chronic hepatitis, or (rarely) result in acute liver failure. Chronic hepatitis may progress to scarring of the liver (cirrhosis), liver failure, and liver cancer. Hepatitis is most commonly caused by the virus ''hepatovirus A'', ''hepatitis B virus, B'', ''hepatitis C virus, C'', ''hepatitis D virus, D'', and ''hepatitis E virus, E''. Other Viral hepatitis, viruses can also cause liver inflammation, including cytomegalovirus, Epstein–Barr virus, ...
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Brain & Development
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as vision, hearing, and olfaction. Being the most specialized organ, it is responsible for receiving information from the sensory nervous system, processing that information (thought, cognition, and intelligence) and the coordination of motor control (muscle activity and endocrine system). While invertebrate brains arise from paired segmental ganglia (each of which is only responsible for the respective body segment) of the ventral nerve cord, vertebrate brains develop axially from the midline dorsal nerve cord as a vesicular enlargement at the rostral end of the neural tube, with centralized control over all body segments. All vertebrate brains can be embryonically divided into three parts: the forebrain (prosencephalon, subdivided i ...
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Neurology (journal)
''Neurology'' is a weekly peer-reviewed medical journal covering research in neurology. It is published by Wolters Kluwer on behalf of the American Academy of Neurology, of which it is the official journal. It has been edited since April 2020 by José G. Merino (Georgetown University). Previous editors-in-chief The following persons have been editors-in-chief: * Russell N. DeJong (1951-1977; University of Michigan Medical School), founding editor-in-chief * Lewis P. Rowland (1977-1987; Columbia University) * Robert B. Daroff (1987-1997; Case Western Reserve University School of Medicine) * Robert C. Griggs (1997-2007; University of Rochester Medical Center) * John H. Noseworthy (2007-2009; Mayo Clinic) * Robert A. Gross (2009-2020; University of Rochester Medical Center) Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'' by Clarivate, the journal has a 2022 impact factor The impact factor (IF) or journal impac ...
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