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History Of Immunology
The following are notable events in the Timeline of immunology: * 1550 BCE – The Ebers papyrus recommends placing a poultice on a tumor and then making an incision, which would induce infection and cause regression of the tumor * 1549 – The earliest account of inoculation of smallpox (variolation) occurs in Wan Quan's (1499–1582) ''Douzhen Xinfa'' (痘疹心法)Needham, Joseph. (2000). Science and Civilization in China: Volume 6, Biology and Biological Technology, Part 6, Medicine''. Cambridge: Cambridge University Press. Page 134. * 1718 – Smallpox inoculation in Ottoman Empire realized by West, and Henry Kipkosgei, recorded the positive effects of variolation * 1761 – A case of breast cancer cured after ulcerating and getting infected is reported by Lambergen * 1796 – First demonstration of smallpox vaccination (Edward Jenner) * 1808–1813 – First experimental demonstration of the germ theory of disease (Agostino Bassi, though he does not formally propose ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ebers Papyrus
The Ebers Papyrus, also known as Papyrus Ebers, is an Egyptian medical papyrus of herbal knowledge dating to (the late Second Intermediate Period or early New Kingdom). Among the oldest and most important medical papyri of Ancient Egypt, it was purchased at Luxor in the winter of 1873–1874 by the German Egyptologist Georg Ebers. It is currently kept at the Leipzig University Library in Germany. Manuscript The papyrus was written in Ancient Egypt in , during the late Second Intermediate Period or early New Kingdom, but it is believed to have been copied from earlier Egyptian texts. The Ebers Papyrus is a 110-page scroll, which is about 20 meters long. Along with the Kahun Gynaecological Papyrus (), the Edwin Smith Papyrus (), the Hearst papyrus (), the Brugsch Papyrus (), and the London Medical Papyrus (), the Ebers Papyrus is among the oldest preserved medical documents. The Brugsch and the London Medical papyri share some of the same information as the Ebers Papyr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louis Pasteur
Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, Fermentation, microbial fermentation, and pasteurization, the last of which was named after him. His research in chemistry led to remarkable breakthroughs in the understanding of the causes and preventions of diseases, which laid down the foundations of hygiene, public health and much of modern medicine. Pasteur's works are credited with saving millions of lives through the developments of vaccines for rabies vaccine, rabies and anthrax vaccine, anthrax. He is regarded as one of the founders of modern bacteriology and has been honored as the "father of bacteriology" and the "father of microbiology" (together with Robert Koch; the latter epithet also attributed to Antonie van Leeuwenhoek). Pasteur was responsible for disproving the doctrine of spontaneous generation. Under the auspices of the French Aca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pierre Roux
Pierre is a masculine given name. It is a French form of the name Peter. Pierre originally meant "rock" or "stone" in French (derived from the Greek word πέτρος (''petros'') meaning "stone, rock", via Latin "petra"). It is a translation of Aramaic כיפא (''Kefa),'' the nickname Jesus gave to apostle Simon Bar-Jona, referred in English as Saint Peter. Pierre is also found as a surname. People with the given name * Monsieur Pierre, Pierre Jean Philippe Zurcher-Margolle (c. 1890–1963), French ballroom dancer and dance teacher * Pierre (footballer), Lucas Pierre Santos Oliveira (born 1982), Brazilian footballer * Pierre, Baron of Beauvau (c. 1380–1453) * Pierre, Duke of Penthièvre (1845–1919) * Pierre, marquis de Fayet (died 1737), French naval commander and Governor General of Saint-Domingue * Prince Pierre, Duke of Valentinois (1895–1964), father of Rainier III of Monaco * Pierre Affre (1590–1669), French sculptor * Pierre Agostini, French physicist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diphtheria
Diphtheria is an infection caused by the bacteria, bacterium ''Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild Course (medicine), clinical course, but in some outbreaks, the mortality rate approaches 10%. Signs and symptoms may vary from mild to severe, and usually start two to five days after exposure. Symptoms often develop gradually, beginning with a sore throat and fever. In severe cases, a grey or white patch develops in the throat, which can block the airway, and create a barking cough similar to what is observed in croup. The neck may also swell, in part due to the enlargement of the facial lymph nodes. Diphtheria can also involve the skin, eyes, or genitals, and can cause complications, including myocarditis (which in itself can result in an cardiac arrhythmia, abnormal heart rate), peripheral neuropathy, inflammation of nerves (which can result in paralysis), proteinuria, kidney problems, and bleeding problems due to thrombocytopenia, low ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pierre Paul Émile Roux
Pierre is a masculine given name. It is a French form of the name Peter. Pierre originally meant "rock" or "stone" in French (derived from the Greek word πέτρος (''petros'') meaning "stone, rock", via Latin "petra"). It is a translation of Aramaic כיפא (''Kefa),'' the nickname Jesus gave to apostle Simon Bar-Jona, referred in English as Saint Peter. Pierre is also found as a surname. People with the given name * Monsieur Pierre, Pierre Jean Philippe Zurcher-Margolle (c. 1890–1963), French ballroom dancer and dance teacher * Pierre (footballer), Lucas Pierre Santos Oliveira (born 1982), Brazilian footballer * Pierre, Baron of Beauvau (c. 1380–1453) * Pierre, Duke of Penthièvre (1845–1919) * Pierre, marquis de Fayet (died 1737), French naval commander and Governor General of Saint-Domingue * Prince Pierre, Duke of Valentinois (1895–1964), father of Rainier III of Monaco * Pierre Affre (1590–1669), French sculptor * Pierre Agostini, French physicist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elie Metchnikoff
Elie may refer to: People * Elie (given name) * Elie (surname) Places *Elie, Fife, a village in Scotland, now part of the town of Elie and Earlsferry *Elie, Manitoba, Canada **Elie, Manitoba tornado See also *Elie Hall, Grenada *Elie House, country house in Elie, Fife, Scotland * *Eli (other) *Elia (other) *Élie, the French equivalent of "Elias" or "Elijah" *Ellie (other) Ellie or Elly is a given name and nickname. It may also refer to: __NOTOC__ Arts and entertainment * ''Ellie'' (film), a 1984 comedy * "Ellie" (''CSI''), an episode of the American crime drama ''CSI'' * "Ellie" (''The West Wing''), an episode of ... * Ely (surname) {{disambiguation, given name, surname ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Fehleisen
Friedrich Fehleisen () (1854–1924) was a German surgeon whose work focused on streptococcal bacteria. Dr. Fehleisen's work played a necessary role in the eventual uncovering of the etiology of many streptococcal illnesses. He made integral contributions to modern medicine's understanding of the ''Streptococcus pyogenes'' organism. He was born in Reutlingen, Württemberg, in 1854, and died in San Francisco, California, in 1924. ''S. pyogenes'' and erysipelas In 1883, he became the first person to culture and collect ''Streptococcus pyogenes'', which causes scarlet fever and other streptococcal illnesses. He cultured it from perierysipelas lesions on humans. One year later, the organism received its current name from Rosenbach. German physician Friedrich Loeffler subsequently demonstrated the presence of streptococci in the throats of patients with scarlet fever. Additionally, Dr. Fehleisen uncovered the etiology of erysipelas, which is an acute streptococcal bacterial infectio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptococcus Pyogenes
''Streptococcus pyogenes'' is a species of Gram-positive, aerotolerant bacteria in the genus '' Streptococcus''. These bacteria are extracellular, and made up of non-motile and non-sporing cocci (round cells) that tend to link in chains. They are clinically important for humans, as they are an infrequent, but usually pathogenic, part of the skin microbiota that can cause group A streptococcal infection. ''S. pyogenes'' is the predominant species harboring the Lancefield group A antigen, and is often called group A ''Streptococcus'' (GAS). However, both '' Streptococcus dysgalactiae'' and the '' Streptococcus anginosus'' group can possess group A antigen as well. Group A streptococci, when grown on blood agar, typically produce small (2–3 mm) zones of beta-hemolysis, a complete destruction of red blood cells. The name group A (beta-hemolytic) ''Streptococcus'' is thus also used. The species name is derived from Greek words meaning 'a chain' () of berries ( atiniz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paul Ehrlich
Paul Ehrlich (; 14 March 1854 – 20 August 1915) was a Nobel Prize-winning German physician and scientist who worked in the fields of hematology, immunology and antimicrobial chemotherapy. Among his foremost achievements were finding a cure for syphilis in 1909 and inventing an important modification of the technique for Gram staining bacteria. The methods he developed for staining tissue made it possible to distinguish between different types of blood cells, which led to the ability to diagnose numerous Hematology, blood diseases. His laboratory discovered arsphenamine (Salvarsan), the first antibiotic and first effective medicinal treatment for syphilis, thereby initiating and also naming the concept of chemotherapy. Ehrlich introduced the concept of a Magic bullet (medicine), magic bullet. He also made a decisive contribution to the development of an antiserum to combat diphtheria and conceived a method for standardising therapeutic Drug, serums. In 1908, he received the No ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mast Cell
A mast cell (also known as a mastocyte or a labrocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. Specifically, it is a type of granulocyte derived from the myeloid stem cell that is a part of the immune and neuroimmune systems. Mast cells were discovered by Friedrich von Recklinghausen and later rediscovered by Paul Ehrlich in 1877. Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing, angiogenesis, immune tolerance, defense against pathogens, and vascular permeability in brain tumors. The mast cell is very similar in both appearance and function to the basophil, another type of white blood cell. Although mast cells were once thought to be tissue-resident basophils, it has been shown that the two cells develop from different hematopoietic lineages and thus cannot be the same cells. Structure Mast cells ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Koch
Heinrich Hermann Robert Koch ( ; ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology. As such he is popularly nicknamed the father of microbiology (with Louis Pasteur), and as the father of medical bacteriology. His discovery of the anthrax bacterium ('' Bacillus anthracis'') in 1876 is considered as the birth of modern bacteriology. Koch used his discoveries to establish that germs "could cause a specific disease" and directly provided proofs for the germ theory of diseases, therefore creating the scientific basis of public health, saving millions of lives. For his life's work Koch is seen as one of the founders of modern medicine. While working as a private physician, Koch developed many innovative techniques in microbiology. He was the first to use the oil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erysipelas
Erysipelas () is a relatively common bacterial infection of the superficial layer of the skin ( upper dermis), extending to the superficial lymphatic vessels within the skin, characterized by a raised, well-defined, tender, bright- red rash, typically on the face or legs, but which can occur anywhere on the skin. It is a form of cellulitis and is potentially serious. Erysipelas is usually caused by the bacterium '' Streptococcus pyogenes'', also known as group A, β-hemolytic streptococci, which enters the body through a break in the skin, such as a scratch or an insect bite. It is more superficial than cellulitis and is typically more raised and demarcated. The term comes from the Greek ἐρυσίπελας (''erysípelas''), meaning red skin. In animals, erysipelas is a disease caused by infection with the bacterium '' Erysipelothrix rhusiopathiae''. In animals, it is called diamond skin disease, and occurs especially in pigs. Heart valves and skin are affected. ''E. rhus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
