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History Of Computed Tomography
The history of X-ray computed tomography dates back to at least 1917 with the mathematical theory of the Radon transform In October 1963, William H. Oldendorf received a U.S. patent for a "radiant energy apparatus for investigating selected areas of interior objects obscured by dense material". The first clinical CT scan was performed in 1971 using a scanner invented by Sir Godfrey Hounsfield. Mathematical theory The mathematical theory behind computed tomographic reconstruction dates back to 1917 with the invention of the Radon transform by Austrian mathematician Johann Radon, who showed mathematically that a function could be reconstructed from an infinite set of its projections. In 1937, Polish mathematician Stefan Kaczmarz developed a method to find an approximate solution to a large system of linear algebraic equations. This, along with Allan McLeod Cormack's theoretical and experimental work, laid the foundation for the algebraic reconstruction technique, which was ada ...
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Zuse Institute Berlin
The Zuse Institute Berlin (abbreviated ZIB, or ''Konrad-Zuse-Zentrum für Informationstechnik Berlin'') is a research institute for applied mathematics and computer science on the campus of Freie Universität Berlin in Dahlem, Berlin, Germany. The ZIB was founded by law as a statutory establishment and as a non-university research institute of the State of Berlin in 1984. In close interdisciplinary cooperation with the Berlin universities and scientific institutions Zuse Institute implements research and development in the field of information technology with a particular focus on application-oriented algorithmic mathematics and practical computer science. ZIB also provides high-performance computer capacity as an accompanying service as part of the ''Network of high performance computers in Northern Germany'' (Norddeutscher Verbund von Hoch- und Höchstleistungsrechnern (HLRN)). Konrad Zuse, born in Berlin in 1910, is the namesake of the ZIB. SCIP (optimization software) ...
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United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the European mainland, continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The United Kingdom includes the island of Great Britain, the north-eastern part of the island of Ireland, and many List of islands of the United Kingdom, smaller islands within the British Isles. Northern Ireland shares Republic of Ireland–United Kingdom border, a land border with the Republic of Ireland; otherwise, the United Kingdom is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. The total area of the United Kingdom is , with an estimated 2020 population of more than 67 million people. The United Kingdom has evolved from a series of annexations, unions and separations of constituent countries over several hundred years. The Treaty of Union between ...
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Hayes, Hillingdon
Hayes is a town in west London, historically situated within the county of Middlesex, and now part of the London Borough of Hillingdon. The town's population, including its localities Hayes End, Harlington and Yeading, was recorded as 83,564 in the 2011 census. It is situated west of Charing Cross, or east of Slough. The Grand Union Canal flows through the heart of Hayes, accompanied by the Great Western Main Line and significant industry, a town centre, residential areas and country parks. Hayes has a long history. The area appears in the ''Domesday Book'' (1086). Landmarks in the area include the Grade II* listed Parish Church, St Mary's – the central portion of the church survives from the twelfth century and it remains in use (the church dates back to 830 A.D.) – and Barra Hall, a Grade II listed manor house. The town's oldest public house – the Adam and Eve, on the Uxbridge Road – though not the original seventeenth-century structure, has remained on the same ...
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Minicomputers
A minicomputer, or colloquially mini, is a class of smaller general purpose computers that developed in the mid-1960s and sold at a much lower price than mainframe and mid-size computers from IBM and its direct competitors. In a 1970 survey, ''The New York Times'' suggested a consensus definition of a minicomputer as a machine costing less than (), with an input-output device such as a teleprinter and at least four thousand words of memory, that is capable of running programs in a higher level language, such as Fortran or BASIC. The class formed a distinct group with its own software architectures and operating systems. Minis were designed for control, instrumentation, human interaction, and communication switching as distinct from calculation and record keeping. Many were sold indirectly to original equipment manufacturers (OEMs) for final end use application. During the two decade lifetime of the minicomputer class (1965–1985), almost 100 companies formed and only a half ...
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Radiologic Diagnostics
Radiology ( ) is the medical discipline that uses medical imaging to diagnose diseases and guide their treatment, within the bodies of humans and other animals. It began with radiography (which is why its name has a root referring to radiation), but today it includes all imaging modalities, including those that use no electromagnetic radiation (such as ultrasonography and magnetic resonance imaging), as well as others that do, such as computed tomography (CT), fluoroscopy, and nuclear medicine including positron emission tomography (PET). Interventional radiology is the performance of usually minimally invasive medical procedures with the guidance of imaging technologies such as those mentioned above. The modern practice of radiology involves several different healthcare professions working as a team. The radiologist is a medical doctor who has completed the appropriate post-graduate training and interprets medical images, communicates these findings to other physicians by ...
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Focal Plane Tomography
In radiography, focal plane tomography is tomography (imaging a single plane, or slice, of an object) by simultaneously moving the X-ray generator and X-ray detector so as to keep a consistent exposure of only the plane of interest during image acquisition. This was the main method of obtaining tomographs in medical imaging until the late-1970s. It has since been largely replaced by more advanced imaging techniques such as CT and MRI. It remains in use today in a few specialized applications, such as for acquiring orthopantomographs of the jaw in dental radiography. Focal plane tomography’s development began in the 1930s as a means of reducing the problem of superimposition of structures which is inherent to projectional radiography. It was invented in parallel by, among others, by the French physician Bocage, the Italian radiologist Alessandro Vallebona and the Dutch radiologist Bernard George Ziedses des Plantes. Technique Focal plane tomography generally uses mechanic ...
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Intestinal Atresia
Intestinal atresia is any congenital malformation of the structure of the intestine that causes bowel obstruction. The malformation can be a narrowing (stenosis), absence or malrotation of a portion of the intestine. These defects can either occur in the small or large intestine. Symptoms and signs The most prominent symptom of intestinal atresia is bilious vomiting soon after birth. This is most common in jejunal atresia. Other features include abdominal distension and failure to pass meconium. The distension is more generalised the further down the bowel the atresia is located and is thus most prominent with ileal atresia. Inability to pass stool is most common with duodenal or jejunal atresia; if stool is passed, it may be small, mucus-like and grey. Occasionally, there may be jaundice, which is most common in jejunal atresia. Abdominal tenderness or an abdominal mass are not generally seen as symptoms of intestinal atresia. Rather, abdominal tenderness is a symptom of t ...
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Intussusception (medical Disorder)
Intussusception is a medical condition in which a part of the intestine folds into the section immediately ahead of it. It typically involves the small bowel and less commonly the large bowel. Symptoms include abdominal pain which may come and go, vomiting, abdominal bloating, and bloody stool. It often results in a small bowel obstruction. Other complications may include peritonitis or bowel perforation. The cause in children is typically unknown; in adults a ''lead point'' is sometimes present. Risk factors in children include certain infections, diseases like cystic fibrosis, and intestinal polyps. Risk factors in adults include endometriosis, bowel adhesions, and intestinal tumors. Diagnosis is often supported by medical imaging. In children, ultrasound is preferred while in adults a CT scan is preferred. Intussusception is an emergency requiring rapid treatment. Treatment in children is typically by an enema with surgery used if this is not successful. Dexamethasone ...
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Acute Pancreatitis
Acute pancreatitis (AP) is a sudden inflammation of the pancreas. Causes in order of frequency include: 1) a gallstone impacted in the common bile duct beyond the point where the pancreatic duct joins it; 2) heavy alcohol use; 3) systemic disease; 4) trauma; 5) and, in minors, mumps. Acute pancreatitis may be a single event; it may be recurrent; or it may progress to chronic pancreatitis. Mild cases are usually successfully treated with conservative measures: hospitalization, pain control, nothing by mouth, intravenous nutritional support, and intravenous fluid rehydration. Severe cases often require admission to an intensive care unit to monitor and manage complications of the disease. Complications are associated with a high mortality, even with optimal management. Signs and symptoms Common *severe epigastric pain (upper abdominal pain) radiating to the back in 50% of cases *nausea *vomiting * loss of appetite *fever * chills (shivering) * hemodynamic instability, i ...
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Ogilvie Syndrome
Ogilvie syndrome is the acute dilatation of the colon in the absence of any mechanical obstruction in severely ill patients. Acute colonic pseudo-obstruction is characterized by massive dilatation of the cecum (diameter > 10 cm) and right colon on abdominal X-ray. It is a type of megacolon, sometimes referred to as "acute megacolon," to distinguish it from toxic megacolon. The condition carries the name of the British surgeon Sir William Heneage Ogilvie (1887–1971), who first reported it in 1948. Signs and symptoms Usually the patient has abdominal distention, pain and altered bowel movements. There may also be nausea and vomiting. Cause Ogilvie syndrome may occur after surgery, especially following coronary artery bypass surgery and total joint replacement. Drugs that disturb colonic motility (such as anticholinergics or opioid analgesics) contribute to the development of this condition. Pathophysiology The exact mechanism is not known. The probable explanation is imb ...
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Small Bowel Obstruction
Bowel obstruction, also known as intestinal obstruction, is a mechanical or functional obstruction of the intestines which prevents the normal movement of the products of digestion. Either the small bowel or large bowel may be affected. Signs and symptoms include abdominal pain, vomiting, bloating and not passing gas. Mechanical obstruction is the cause of about 5 to 15% of cases of severe abdominal pain of sudden onset requiring admission to hospital. Causes of bowel obstruction include adhesions, hernias, volvulus, endometriosis, inflammatory bowel disease, appendicitis, tumors, diverticulitis, ischemic bowel, tuberculosis and intussusception. Small bowel obstructions are most often due to adhesions and hernias while large bowel obstructions are most often due to tumors and volvulus. The diagnosis may be made on plain X-rays; however, CT scan is more accurate. Ultrasound or MRI may help in the diagnosis of children or pregnant women. The condition may be treated conserv ...
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