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Hexachlorophene
Hexachlorophene, also known as Nabac, is an organochlorine compound that was once widely used as a disinfectant. The compound occurs as a white odorless solid, although commercial samples can be off-white and possess a slightly phenolic odor. It is insoluble in water but dissolves in acetone, ethanol, diethyl ether, and chloroform. In medicine, hexachlorophene is useful as a topical anti-infective and anti-bacterial agent. It is also used in agriculture as a soil fungicide, plant bactericide, and acaricide. Production Hexachlorophene is produced by alkylation of 2,4,5- trichlorophenol with formaldehyde. Related antiseptics are prepared similarly, e.g., bromochlorophene and dichlorophene. Safety The LD50 (oral, rat) is 59 mg/kg, indicating that the compound is relatively toxic. It is not mutagenic nor teratogenic according to Ullmann's Encyclopedia, but "embryotoxic and produces some teratogenic effects" according to the International Agency for Research on Cancer. 2,3 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Disinfectant
A disinfectant is a chemical substance or compound used to inactivate or destroy microorganisms on inert surfaces. Disinfection does not necessarily kill all microorganisms, especially resistant bacterial spores; it is less effective than sterilization, which is an extreme physical or chemical process that kills all types of life. Disinfectants are generally distinguished from other antimicrobial agents such as antibiotics, which destroy microorganisms within the body, and antiseptics, which destroy microorganisms on living tissue. Disinfectants are also different from biocides—the latter are intended to destroy all forms of life, not just microorganisms. Disinfectants work by destroying the cell wall of microbes or interfering with their metabolism. It is also a form of decontamination, and can be defined as the process whereby physical or chemical methods are used to reduce the amount of pathogenic microorganisms on a surface. Disinfectants can also be used to dest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phisoderm
Phisoderm is a skin detergent which assists persons who are allergic to soap and Phisohex, a detergent and sudsless cleanser which prevents the spread of infections. In the 1950s, both Phisoderm and Phisohex were manufactured by Winthrop Laboratories. Earlier, the product was made by Fairchild Brothers & Foster. Phisoderm was developed by B. Thurber Guild (1886–1958), a physician and pharmaceutical manufacturer. Guild practiced medicine in Boston, Massachusetts, and was a specialist in allergies.''Dr. B. Thurber Guild, Allergist, Was 72'', ''The New York Times'', June 17, 1958, pg. 29. The brand is currently owned by Mentholatum. Withdrawal from sale and reinstatement Both Phisoderm and Phisohex were removed by drugstores and retail outlet stores when the Food and Drug Administration halted the production and distribution of products containing more than 1% of hexachlorophene, in September 1972." Germicide Limit Stirs Confusion", ''The New York Times'', September 24, 1972, pg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Times Beach, Missouri
Times Beach is a ghost town in St. Louis County, Missouri, St. Louis County, Missouri, United States, southwest of St. Louis, Missouri, St. Louis and east of Eureka, Missouri, Eureka. Once home to more than two thousand people, the town was completely evacuated in early 1983 due to 2,3,7,8-Tetrachlorodibenzodioxin, TCDD (a type of dioxins and dioxin-like compounds, dioxin) contamination, formerly the largest civilian exposure to the compound in the history of the United States. In 1985, the State of Missouri officially disincorporated the city of Times Beach. The site of Times Beach now houses a Route 66 State Park, state park which opened in 1999. The park commemorates U.S. Route 66, as well as the history of the Times Beach area. The famous U.S. Route 66 highway that stretches from Chicago, Illinois, to Santa Monica, California, Santa Monica, California passed though the community on its southern end. In 2001, the EPA removed Times Beach from its Superfund list. History Tim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organochlorine Compound
Organochlorine chemistry is concerned with the properties of organochlorine compounds, or organochlorides, organic compounds that contain one or more carbon–chlorine bonds. The chloroalkane class (alkanes with one or more hydrogens substituted by chlorine) includes common examples. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious. Organochlorides such as trichloroethylene, tetrachloroethylene, dichloromethane and chloroform are commonly used as solvents and are referred to as "chlorinated solvents". Physical and chemical properties Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. They have highe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Community
The European Economic Community (EEC) was a regional organisation created by the Treaty of Rome of 1957,Today the largely rewritten treaty continues in force as the ''Treaty on the functioning of the European Union'', as renamed by the Lisbon Treaty. aiming to foster economic integration among its member states. It was subsequently renamed the European Community (EC) upon becoming integrated into the Three pillars of the European Union, first pillar of the newly formed European Union (EU) in 1993. In the popular language, the singular ''European Community'' was sometimes inaccurately used in the wider sense of the plural ''European Communities'', in spite of the latter designation covering all the three constituent entities of the first pillar. The EEC was also known as the European Common Market (ECM) in the English-speaking countries, and sometimes referred to as the European Community even before it was officially renamed as such in 1993. In 2009, the EC formally ceased to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acne
Acne ( ), also known as ''acne vulgaris'', is a long-term Cutaneous condition, skin condition that occurs when Keratinocyte, dead skin cells and Sebum, oil from the skin clog hair follicles. Typical features of the condition include comedo, blackheads or whiteheads, pimples, oily skin, and possible scarring. It primarily affects skin with a relatively high number of sebaceous gland, oil glands, including the face, upper part of the chest, and back. The resulting appearance can lead to lack of confidence, anxiety (mood), anxiety, reduced self-esteem, and, in extreme cases, clinical depression, depression or suicidal ideations, thoughts of suicide. Susceptibility to acne is primarily genetic in 80% of cases. The roles of diet and cigarette smoking in the condition are unclear, and neither hygiene, cleanliness nor exposure to sunlight are associated with acne. In both sexes, hormones called androgens appear to be part of the underlying mechanism, by causing increased production ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Mennen Company
Mennen is a brand owned in most parts of the world by the Colgate-Palmolive Company. Its most notable product, Mennen Speed Stick, with its fougère perfume and green wide stick, was the US market leader among deodorants and antiperspirants for men for many years. It was also noted for its Lady Speed Stick deodorant and Teen Spirit deodorant, which was the leader in teenage girls' deodorants during the early 1990s. In France, the Mennen branding is owned by L'Oréal through its Mennen-LASCAD subsidiary, for a line of men's grooming products. History The Mennen Company was founded in 1878 by Gerhard Heinrich Mennen, an immigrant to America from Germany. His first product was a borated talcum-based powder, an innovation at the time. The company was originally located in Newark, New Jersey, US, moving to Morristown, New Jersey, in 1953, where it manufactured and sold over-the-counter pharmaceuticals and personal products such as the Skin Bracer, Speed Stick, and Baby Magi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germicide
An antiseptic ( and ) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis, infection, or putrefaction. Antiseptics are generally distinguished from ''antibiotics'' by the latter's ability to safely destroy bacteria within the body, and from ''disinfectants'', which destroy microorganisms found on non-living objects. Antibacterials include antiseptics that have the proven ability to act against bacteria. Microbicides which destroy virus particles are called viricides or antivirals. Antifungals, also known as antimycotics, are pharmaceutical fungicides used to treat and prevent mycosis (fungal infection). Surgery Antiseptic practices evolved in the 19th century through multiple individuals. Ignaz Semmelweis showed already in 1847-1848 that hand washing prior to delivery reduced puerperal fever. Despite this, many hospitals continued to practice surgery in unsanitary conditions, with some surgeons taking pride in their ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Industrial Accident
A work accident, workplace accident, occupational accident, or accident at work is a "discrete occurrence in the course of work" leading to physical or mental occupational injury. According to the International Labour Organization (ILO), more than 337 million accidents happen on the job each year, resulting, together with occupational diseases, in more than 2.3 million deaths annually. The phrase "in the course of work" can include work-related accidents happening off the company's premises, and can include accidents caused by third parties, according to Eurostat. The definition of work accident includes accidents occurring "while engaged in an economic activity, or at work, or carrying on the business of the employer" according to the ILO. The phrase "physical or mental harm" means any injury, disease, or death. Occupational accidents differ from occupational diseases as accidents are unexpected and unplanned occurrences (e.g., mine collapse), while occupational diseases are " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilateria, bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and Coelenterata, diploblasts. It is a structure composed of nervous tissue positioned along the Anatomical_terms_of_location#Rostral,_cranial,_and_caudal, rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain, though precursor structures exist in onychophorans, gastropods and lancelets. The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baby Powder
Baby powder is an astringent powder (substance), powder used for preventing diaper rash and for Cosmetics, cosmetic uses. It may be composed of talc (in which case it is also called talcum powder), corn starch or potato starch. It may contain additional ingredients such as fragrances. Baby powder can also be used as a dry shampoo, cleaning agent (to remove grease stains), and air freshener. History Talcum baby powder was pioneered in the early 1890s by Frederick Barnett Kilmer, the first scientific director of the then-fledging healthcare company Johnson and Johnson. in 1892, Kilmer prescribed talcum powder to ease skin irritation from Johnson and Johnson's medical plasters. The powder was soon found to ease irritation in babies skin, and by 1894 Johnson's baby powder was being mass produced as its own product. Health risks Talcum powder, if inhaled, may cause aspiration pneumonia and granuloma. Severe cases may lead to chronic respiratory problems and death. The particles i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
