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HODE (other)
HODE may refer to: * 9-Hydroxyoctadecadienoic acid (9-HODE) * 13-Hydroxyoctadecadienoic acid 13-Hydroxyoctadecadienoic acid (13-HODE) is the commonly used term for 13(''S'')-hydroxy-9''Z'',11''E''-octadecadienoic acid (13(''S'')-HODE). The production of 13(''S'')-HODE is often accompanied by the production of its stereoisomer, 13(''R'') ... (13-HODE) See also * Hode, Kentucky {{Disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
9-Hydroxyoctadecadienoic Acid
9-Hydroxyoctadecadienoic acid (or 9-HODE) has been used in the literature to designate either or both of two stereoisomer metabolites of the essential fatty acid, linoleic acid: 9(''S'')-hydroxy-10(''E''),12(''Z'')-octadecadienoic acid (9(''S'')-HODE) and 9(''R'')-hydroxy-10(''E''),12(''Z'')-octadecadienoic acid (9(''R'')-HODE); these two metabolites differ in having their hydroxy residues in the ''S'' or ''R'' configurations, respectively. The accompanying figure gives the structure for 9(''S'')-HETE. Two other 9-hydroxy linoleic acid derivatives occur in nature, the 10''E'',12''E'' isomers of 9(''S'')-HODE and 9''(R'')-HODE viz., 9(''S'')-hydroxy-10''E'',12''E''-octadecadienoic acid (9(''S'')-''EE''-HODE) and 9(''R'')-hydroxy-10''E'',12''E''-octadecadienoic acid (13(''R'')-''EE''-HODE); these two derivatives have their double bond at carbon 12 in the ''E'' or trans configuration as opposed to the ''Z'' or cis configuration. The four 9-HODE isomers, particularly under condit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
13-Hydroxyoctadecadienoic Acid
13-Hydroxyoctadecadienoic acid (13-HODE) is the commonly used term for 13(''S'')-hydroxy-9''Z'',11''E''-octadecadienoic acid (13(''S'')-HODE). The production of 13(''S'')-HODE is often accompanied by the production of its stereoisomer, 13(''R'')-hydroxy-9''Z'',11''E''-octadecadienoic acid (13(''R'')-HODE). The adjacent figure gives the structure for the (''S'') stereoisomer of 13-HODE. Two other naturally occurring 13-HODEs that may accompany the production of 13(''S'')-HODE are its cis-trans (i.e., 9''E'',11''E'') isomers viz., 13(''S'')-hydroxy-9''E'',11''E''-octadecadienoic acid (13(''S'')-''EE''-HODE) and 13(''R'')-hydroxy-9''E'',11''E''-octadecadienoic acid (13(''R'')-''EE''-HODE). Studies credit 13(''S'')-HODE with a range of clinically relevant bioactivities; recent studies have assigned activities to 13(''R'')-HODE that differ from those of 13(''S'')-HODE; and other studies have proposed that one or more of these HODEs mediate physiological and pathological responses, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |