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HLA-B46
HLA-B46 (B46) is an HLA- B serotype. The serotype identifies the gene products of HLA-B*4601 allele. B*4601 resulted from a rare, interlocus, gene conversion between B62, probably B*1501, and a HLA-C allele. B*4601 is the most common HLA-B allele that does not have an origin within Africa, and estimated 400 million people in Eastern Asia carry a B46 allele. When found B*4601 segregates with only 2 HLA-Cw alleles, A limited number of HLA-A and HLA-DRB1 alleles suggesting that the allele recently expanded from a limited sized group within SE Asia. Extremely low frequencies outside of Eastern Asia are indicators of a recent expansion of B46 from a recently small population. The frequency distribution suggests the ancestral B46 population was in SE China, or, potentially Burma (Myanmar or Laos, untested). B46 in Asia correlates with wet-rice farming. The exceptions are notable, it has been found in the Nivkhi on north-eastern Sakalin Island, the Ainu, and the Nivkhi-related (genet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
HLA-B
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria. HLA is the human version of the major histocompatibility complex (MHC), a gene family that occurs in many species. Genes in this complex are separated into three basic groups: class I, class II, and class III. In humans, the HLA-B gene and two related genes, HLA-A and HLA-C, are the major genes in MHC class I. MHC class I genes provide instructions for making proteins that are present on the surface of almost all cells. On the cell surface, these proteins are bound to protein fragments (peptides) that have been exported from within the cell. MHC class I proteins display these peptides to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
China
China, officially the People's Republic of China (PRC), is a country in East Asia. With population of China, a population exceeding 1.4 billion, it is the list of countries by population (United Nations), second-most populous country after India, representing 17.4% of the world population. China spans the equivalent of five time zones and Borders of China, borders fourteen countries by land across an area of nearly , making it the list of countries and dependencies by area, third-largest country by land area. The country is divided into 33 Province-level divisions of China, province-level divisions: 22 provinces of China, provinces, 5 autonomous regions of China, autonomous regions, 4 direct-administered municipalities of China, municipalities, and 2 semi-autonomous special administrative regions. Beijing is the country's capital, while Shanghai is List of cities in China by population, its most populous city by urban area and largest financial center. Considered one of six ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Naxi People
The Nakhi, Nashi, or Naxi (; Naxi language, Naxi: ) are a people inhabiting the Hengduan Mountains abutting the Eastern Himalayas in the northwestern part of Yunnan Provinces of China, Province, as well as the southwestern part of Sichuan Province in China. The Nakhi are thought to have come originally from northwestern China, migrating south toward Tibetan people, Tibetan-populated regions, and usually inhabiting the most fertile riverside land, driving the other competing tribes farther up the hillsides onto less fertile land. The Nakhi traded over the dangerous overland trading links with Lhasa and India, on the so-called tea and horse caravan routes. The Nakhi form one of the 56 ethnic groups officially recognized by the People's Republic of China. The official Chinese government classification includes the Mosuo as part of the Nakhi people. Nakhi culture is largely its own native Dongba religious, literary, and farming practices, influenced by the Confucian roots of Han ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Japan
Japan is an island country in East Asia. Located in the Pacific Ocean off the northeast coast of the Asia, Asian mainland, it is bordered on the west by the Sea of Japan and extends from the Sea of Okhotsk in the north to the East China Sea in the south. The Japanese archipelago consists of four major islands—Hokkaido, Honshu, Shikoku, and Kyushu—and List of islands of Japan, thousands of smaller islands, covering . Japan has a population of over 123 million as of 2025, making it the List of countries and dependencies by population, eleventh-most populous country. The capital of Japan and List of cities in Japan, its largest city is Tokyo; the Greater Tokyo Area is the List of largest cities, largest metropolitan area in the world, with more than 37 million inhabitants as of 2024. Japan is divided into 47 Prefectures of Japan, administrative prefectures and List of regions of Japan, eight traditional regions. About three-quarters of Geography of Japan, the countr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Aichi
is a prefecture of Japan located in the Chūbu region of Honshū. Aichi Prefecture has a population of 7,461,111 () and a geographic area of with a population density of . Aichi Prefecture borders Mie Prefecture to the west, Gifu Prefecture and Nagano Prefecture to the north, and Shizuoka Prefecture to the east. Nagoya is the capital and largest city of the prefecture. Overview Nagoya is the capital and largest city of Aichi Prefecture, and the fourth-largest city in Japan. Other major cities include Toyota, Okazaki, and Ichinomiya. Aichi Prefecture and Nagoya form the core of the Chūkyō metropolitan area, the third-largest metropolitan area in Japan and one of the largest metropolitan areas in the world. Aichi Prefecture is located on Japan's Pacific Ocean coast and forms part of the Tōkai region, a subregion of the Chūbu region and Kansai region. Aichi Prefecture is home to the Toyota Motor Corporation. Aichi Prefecture had many locations with the Higashiyama Zoo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Guangxi
Guangxi,; officially the Guangxi Zhuang Autonomous Region, is an Autonomous regions of China, autonomous region of the China, People's Republic of China, located in South China and bordering Vietnam (Hà Giang Province, Hà Giang, Cao Bằng Province, Cao Bằng, Lạng Sơn Province, Lạng Sơn, and Quảng Ninh Provinces) and the Gulf of Tonkin. Formerly a Provinces of China, province, Guangxi became an autonomous region in 1958. Its current capital is Nanning. Guangxi's location, in mountainous terrain in the far south of China, has placed it on the frontier of Chinese civilization throughout much of History of China, Chinese history. The current name "Guang" means "expanse" and has been associated with the region since the creation of Guang Prefecture in 226 AD. It was given Administrative divisions of the Yuan dynasty, provincial level status during the Yuan dynasty, but even into the 20th century, it was considered an open, wild territory. The abbreviation of the regi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Maonan People
The Maonan people (; Maonan: ''Anan'', literally "local people") are one of the 56 ethnic groups officially recognized by the People's Republic of China. There are a total of 101,192 Maonan as of 2010, mostly living in northern Guangxi and southern Guizhou in southern China. The Maonan people's autonyms are ''ʔai1 na:n6 ''(a Maonan person), ''kjɔŋ5 na:n6'' (the Maonan people). Their language is called ''va6 na:n6'' (Lu 2008:33).Lu, Tian Qiao (2008). ''A Grammar of Maonan''. Boca Raton, Florida: Universal Publishers. . Language Society More than 80% of the Maonan share the same surname: '' Tan'' (). Maonan with the surname ''Tan'' believe that they are descended from the old inhabitants of the province of Hunan that migrated to Guangxi and married Maonan women. Other common surnames found in this ethnic group are: '' Lu'' (卢/盧), '' Liu'' (刘/劉), '' Shi'' (石), '' Qin'' (覃), '' Wei'' (韦/韋) and '' Yuan'' (袁). The towns of the Maonan do not surpass more t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Wuhan
Wuhan; is the capital of Hubei, China. With a population of over eleven million, it is the most populous city in Hubei and the List of cities in China by population, eighth-most-populous city in China. It is also one of the nine National central city, national central cities and the second most livable city in China. Wuhan historically served as a busy city port for commerce and trading with some crucial influences on Chinese history. The name "Wuhan" came from the city's historical origin from the conglomeration of Wuchang, Wuhan, Wuchang, Hankou District, Hankou, and Hanyang District, Hanyang, which are collectively known as the "Three Towns of Wuhan" ( zh, s=武汉三镇, labels=no). Wuhan lies in the eastern Jianghan Plain, at the confluence of the Yangtze river and its largest tributary, the Han River (Hubei), Han River, and is known as "Nine Provinces' Thoroughfare" ( zh, labels=no, t= ). Wuhan was the site of the 1911 Wuchang Uprising against the Qing dynasty which Dyna ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Southern Min
Southern Min (), Minnan ( Mandarin pronunciation: ) or Banlam (), is a group of linguistically similar and historically related Chinese languages that form a branch of Min Chinese spoken in Fujian (especially the Minnan region), most of Taiwan (many citizens are descendants of settlers from Fujian), Eastern Guangdong, Hainan, and Southern Zhejiang. Southern Min dialects are also spoken by descendants of emigrants from these areas in diaspora, most notably in Southeast Asia, such as Singapore, Malaysia, the Philippines, Indonesia, Brunei, Southern Thailand, Myanmar, Cambodia, Southern and Central Vietnam, as well as major cities in the United States, including in San Francisco, in Los Angeles and in New York City. Minnan is the most widely-spoken branch of Min, with approximately 34 million native speakers as of 2025. The most widely spoken Southern Min language is Hokkien, which includes Taiwanese. Other varieties of Southern Min have significant differences from Hok ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Guangzhou
Guangzhou, Chinese postal romanization, previously romanized as Canton or Kwangchow, is the Capital city, capital and largest city of Guangdong Provinces of China, province in South China, southern China. Located on the Pearl River about northwest of Hong Kong and north of Macau, Guangzhou has a history of over 2,200 years and was a major terminus of the Silk Road. The port of Guangzhou serves as a transportation hub for China's fourth largest city and surrounding areas, including Hong Kong. Guangzhou was captured by the United Kingdom, British during the First Opium War and no longer enjoyed a monopoly after the war; consequently it lost trade to other ports such as Hong Kong and Shanghai, but continued to serve as a major entrepôt. Following the Second Battle of Chuenpi in 1841, the Treaty of Nanking was signed between Robert Peel, Sir Robert Peel on behalf of Queen Victoria and Lin Zexu on behalf of Daoguang Emperor, Emperor Xuanzong and ceded British Hong Kong, Hong Kon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Hakka People
The Hakka (), sometimes also referred to as Hakka-speaking Chinese, or Hakka Chinese, or Hakkas, are a southern Han Chinese subgroup whose principal settlements and ancestral homes are dispersed widely across the provinces of southern China and who speak a language that is closely related to Gan Chinese, Gan, a Han Chinese dialect spoken in Jiangxi province. They are differentiated from other southern Han Chinese by their dispersed nature and tendency to occupy marginal lands and remote hilly areas. The Chinese characters for ''Hakka'' () literally mean "guest families". The Hakka have settled in Guangdong, Fujian, Jiangxi, Guangxi, Sichuan, Hunan, Zhejiang, Hainan, and Guizhou in China, as well as in Taoyuan City, Hsinchu County, Miaoli County, Pingtung County, and Kaohsiung City in Taiwan. Their presence is especially prominent in the Lingnan or Liangguang area, comprising the Cantonese-speaking provinces of Guangdong and Guangxi. Despite being partly assimilated to the Can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Hong Kong
Hong Kong)., Legally Hong Kong, China in international treaties and organizations. is a special administrative region of China. With 7.5 million residents in a territory, Hong Kong is the fourth most densely populated region in the world. Hong Kong was established as a colony of the British Empire after the Qing dynasty ceded Hong Kong Island in 1841–1842 as a consequence of losing the First Opium War. The colony expanded to the Kowloon Peninsula in 1860 and was further extended when the United Kingdom obtained a 99-year lease of the New Territories in 1898. Hong Kong was occupied by Japan from 1941 to 1945 during World War II. The territory was handed over from the United Kingdom to China in 1997. Hong Kong maintains separate governing and economic systems from that of mainland China under the principle of one country, two systems. Originally a sparsely populated area of farming and fishing villages,. the territory is now one of the world's most signific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
