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GraphPad Software
GraphPad Software Inc. was a privately held software development corporation until its acquisition by Insight Partners in 2017. The company was named Insightful Science, which itself merged with Dotmatics in 2021. The original software was written by Harvey Motulsky in 1989 and it was co-founded by Motulsky and Earl B. Beutler, Earl Beutler. The company operates in California. Its products include the 2D scientific graphing, biostatistics, curve fitting software GraphPad Prism and the free, web-based statistical calculation software, GraphPad QuickCalcs. GraphPad Prism GraphPad Prism is a commercial scientific 2D graphing and statistics software for Windows and Mac OS desktop computers. Software features include nonlinear regression, with functionalities including the removal of outliers, comparisons of models, comparisons of curves, and interpolation of standard curves. The software allows the automatic updating of results and graphs, and has functionality for displaying err ...
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Insight Partners
Insight Venture Management, LLC (commonly referred to as Insight Partners and previously Insight Venture Partners) is a global venture capital and private equity firm that invests in high-growth technology, software, and internet businesses. The company is headquartered in New York City, also has offices in London, Tel Aviv, and Palo Alto, California, Palo Alto. History Insight Partners was founded in 1995 by Jeff Horing and Jerry Murdock. As of December 31, 2022, the firm managed over $75 billion in regulatory assets under management. Insight Partners has invested in more than 750 companies worldwide and has seen over 55 portfolio companies achieve an Initial public offering, IPO. The firm has an in-house team called Onsite that assists portfolio companies in their growth. In April 2021, Insight Partners raised $1.56 billion for the Insight Partners Opportunities Fund I LP, a separate fund from its primary growth-investment vehicles. Also in 2021, Insight Partners put $15 milli ...
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Dotmatics
Dotmatics is an R&D scientific software company used by scientists in the R&D process. Founded in 2005, the company's primary office is in Boston with 14 offices around the globe. In March 2021, Insightful Science acquired Dotmatics. In April 2022, the two companies consolidated under the Dotmatics brand with Insightful Science CEO Thomas Swalla leading the new Dotmatics. Dotmatics' software is used by 2 million scientists and researchers and 10,000 customers. Dotmatics offers a cloud-based data management platform to support the R&D process and a series of software applications used by scientists that include GraphPad Prism, SnapGene, Geneious Prime, Geneious Biologics, Lab Archives, OMIQ, Protein Metrics, nQuery, Cytapex Bioinformatics, De Novo, SoftGenetics, and M-Star. In October 2023, Dotmatics released a multimodal drug discovery platform named Luma. Luma is a low-code SaaS platform that aggregates relevant data across instruments and software into clean data structures for ...
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Earl B
Earl () is a rank of the nobility in the United Kingdom. In modern Britain, an earl is a member of the peerage, ranking below a marquess and above a viscount. A feminine form of ''earl'' never developed; instead, ''countess'' is used. The title originates in the Old English word , meaning "a man of noble birth or rank". The word is cognate with the Scandinavian form '' jarl''. After the Norman Conquest, it became the equivalent of the continental count. In Scotland, it assimilated the concept of mormaer. Since the 1960s, earldoms have typically been created only for members of the royal family. The last non-royal earldom, Earl of Stockton, was created in 1984 for Harold Macmillan, prime minister from 1957 to 1963. Alternative names for the rank equivalent to "earl" or "count" in the nobility structure are used in other countries, such as the '' hakushaku'' (伯爵) of the post-restoration Japanese Imperial era. Etymology In the 7th century, the common Old English terms fo ...
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Biostatistics
Biostatistics (also known as biometry) is a branch of statistics that applies statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments, the collection and analysis of data from those experiments and the interpretation of the results. History Biostatistics and genetics Biostatistical modeling forms an important part of numerous modern biological theories. Genetics studies, since its beginning, used statistical concepts to understand observed experimental results. Some genetics scientists even contributed with statistical advances with the development of methods and tools. Gregor Mendel started the genetics studies investigating genetics segregation patterns in families of peas and used statistics to explain the collected data. In the early 1900s, after the rediscovery of Mendel's Mendelian inheritance work, there were gaps in understanding between genetics and evolutionary Darwinism. Francis Galton tried to expand Mendel's ...
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MacOS
macOS, previously OS X and originally Mac OS X, is a Unix, Unix-based operating system developed and marketed by Apple Inc., Apple since 2001. It is the current operating system for Apple's Mac (computer), Mac computers. Within the market of Desktop computer, desktop and laptop computers, it is the Usage share of operating systems#Desktop and laptop computers, second most widely used desktop OS, after Microsoft Windows and ahead of all Linux distributions, including ChromeOS and SteamOS. , the most recent release of macOS is MacOS Sequoia, macOS 15 Sequoia, the 21st major version of macOS. Mac OS X succeeded classic Mac OS, the primary Mac operating systems, Macintosh operating system from 1984 to 2001. Its underlying architecture came from NeXT's NeXTSTEP, as a result of NeXT#1997–2006: Acquisition by Apple, Apple's acquisition of NeXT, which also brought Steve Jobs back to Apple. The first desktop version, Mac OS X 10.0, was released on March 24, 2001. Mac ...
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Windows
Windows is a Product lining, product line of Proprietary software, proprietary graphical user interface, graphical operating systems developed and marketed by Microsoft. It is grouped into families and subfamilies that cater to particular sectors of the computing industry – Windows (unqualified) for a consumer or corporate workstation, Windows Server for a Server (computing), server and Windows IoT for an embedded system. Windows is sold as either a consumer retail product or licensed to Original equipment manufacturer, third-party hardware manufacturers who sell products Software bundles, bundled with Windows. The first version of Windows, Windows 1.0, was released on November 20, 1985, as a graphical operating system shell for MS-DOS in response to the growing interest in graphical user interfaces (GUIs). The name "Windows" is a reference to the windowing system in GUIs. The 1990 release of Windows 3.0 catapulted its market success and led to various other product families ...
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Commercial Software
Commercial software, or, seldom, payware, is a computer software that is produced for sale or that serves commercial purposes. Commercial software can be proprietary software or free and open-source software. Background and challenge While software creation by programming is a time and labor-intensive process, comparable to the creation of physical goods, the reproduction, duplication and sharing of software as digital goods is in comparison disproportionately easy. No special machines or expensive additional resources are required, unlike almost all physical goods and products. Once the software is created it can be copied in infinite numbers, for almost zero cost, by anyone. This made commercialization of software for the mass market in the beginning of the computing era impossible. Unlike hardware, it was not seen as trade-able and commercialize-able good. Software was plainly shared for free (hacker culture) or distributed bundled with sold hardware, as part of the ...
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Proprietary Software
Proprietary software is computer software, software that grants its creator, publisher, or other rightsholder or rightsholder partner a legal monopoly by modern copyright and intellectual property law to exclude the recipient from freely sharing the software or modifying it, and—in some cases, as is the case with some patent-encumbered and EULA-bound software—from making use of the software on their own, thereby restricting their freedoms. Proprietary software is a subset of non-free software, a term defined in contrast to free and open-source software; non-commercial licenses such as CC BY-NC are not deemed proprietary, but are non-free. Proprietary software may either be closed-source software or source-available software. Types Origin Until the late 1960s, computers—especially large and expensive mainframe computers, machines in specially air-conditioned computer rooms—were usually leased to customers rather than Sales, sold. Service and all software available ...
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Statistics Software
The following is a list of statistical software. Open-source * ADaMSoft – a generalized statistical software with data mining algorithms and methods for data management * ADMB – a software suite for non-linear statistical modeling based on C++ which uses automatic differentiation * Chronux – for neurobiological time series data * DAP – free replacement for SAS * Environment for DeveLoping KDD-Applications Supported by Index-Structures (ELKI) a software framework for developing data mining algorithms in Java * Epi Info – statistical software for epidemiology developed by Centers for Disease Control and Prevention (CDC). Apache 2 licensed * Fityk – nonlinear regression software (GUI and command line) * GNU Octave – programming language very similar to MATLAB with statistical features * gretl – gnu regression, econometrics and time-series library * intrinsic Noise Analyzer (iNA) – For analyzing intrinsic fluctuations in biochemical systems * jamovi – A fre ...
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Nonlinear Regression
In statistics, nonlinear regression is a form of regression analysis in which observational data are modeled by a function which is a nonlinear combination of the model parameters and depends on one or more independent variables. The data are fitted by a method of successive approximations (iterations). General In nonlinear regression, a statistical model of the form, \mathbf \sim f(\mathbf, \boldsymbol\beta) relates a vector of independent variables, \mathbf, and its associated observed dependent variables, \mathbf. The function f is nonlinear in the components of the vector of parameters \beta, but otherwise arbitrary. For example, the Michaelis–Menten model for enzyme kinetics has two parameters and one independent variable, related by f by: f(x,\boldsymbol\beta)= \frac This function, which is a rectangular hyperbola, is because it cannot be expressed as a linear combination of the two \betas. Systematic error may be present in the independent variables but its ...
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Software Companies Based In California
Software consists of computer programs that instruct the execution of a computer. Software also includes design documents and specifications. The history of software is closely tied to the development of digital computers in the mid-20th century. Early programs were written in the machine language specific to the hardware. The introduction of high-level programming languages in 1958 allowed for more human-readable instructions, making software development easier and more portable across different computer architectures. Software in a programming language is run through a compiler or interpreter to execute on the architecture's hardware. Over time, software has become complex, owing to developments in networking, operating systems, and databases. Software can generally be categorized into two main types: # operating systems, which manage hardware resources and provide services for applications # application software, which performs specific tasks for users The rise of clou ...
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Technology Companies Based In San Diego
Technology is the application of conceptual knowledge to achieve practical goals, especially in a reproducible way. The word ''technology'' can also mean the products resulting from such efforts, including both tangible tools such as utensils or machines, and intangible ones such as software. Technology plays a critical role in science, engineering, and everyday life. Technological advancements have led to significant changes in society. The earliest known technology is the stone tool, used during prehistory, followed by the control of fire—which in turn contributed to the growth of the human brain and the development of language during the Ice Age, according to the cooking hypothesis. The invention of the wheel in the Bronze Age allowed greater travel and the creation of more complex machines. More recent technological inventions, including the printing press, telephone, and the Internet, have lowered barriers to communication and ushered in the knowledge economy. Whi ...
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