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Geschwind–Galaburda Hypothesis
The Geschwind–Galaburda hypothesis is a neurological theory proposed by Norman Geschwind and Albert Galaburda in 1987. The hypothesis posits there are sex differences in cognitive abilities by relating them to lateralisation of brain function. The maturation rates of cerebral hemispheres differ and are mediated by circuiting testosterone levels, which are substantially influenced during the foetal and post-puberty development stages. According to the hypothesis, testosterone delays the maturation of the brain, particularly the left hemisphere, resulting in corresponding regions of the right hemisphere and unaffected areas of the left hemisphere developing more rapidly. This leads to reduced verbal skills and an increased risk of developing language disorders, e.g dyslexia, while a rapid development of the right hemisphere and the skills corresponding to it, such as attention and problem-solving. Focusing on foetal testosterone, the rise in levels hinders the development of the ...
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Norman Geschwind
Norman Geschwind (January 8, 1926 – November 4, 1984) was a pioneering American behavioral neurologist, best known for his exploration of behavioral neurology through disconnection models based on lesion analysis. Early life Norman Geschwind was born on January 8, 1926, in New York City, New York to a Jewish family. He was a student at Boy's High School in Brooklyn, New York. He matriculated into Harvard University in 1942, initially planning to study mathematics. His education was interrupted when drafted into the Army in 1944. After serving for two years, he returned to Harvard University in 1946. Geschwind changed to the Department of Social Relations and studied a combination of social/personality psychology and cultural anthropology. Geschwind later married and had three children, Naomi, David, and Claudia. Medical education and training Geschwind attended Harvard Medical School, intending to become a psychiatrist. His emphasis began to shift after studying neuroanatom ...
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Dyslexia
Dyslexia (), previously known as word blindness, is a learning disability that affects either reading or writing. Different people are affected to different degrees. Problems may include difficulties in spelling words, reading quickly, writing words, "sounding out" words in the head, pronouncing words when reading aloud and understanding what one reads. Often these difficulties are first noticed at school. The difficulties are involuntary, and people with this disorder have a normal desire to learn. People with dyslexia have higher rates of attention deficit hyperactivity disorder (ADHD), developmental language disorders, and difficulties with numbers. Dyslexia is believed to be caused by the interaction of genetic and environmental factors. Some cases run in families. Dyslexia that develops due to a traumatic brain injury, stroke, or dementia is sometimes called "acquired dyslexia" or alexia. The underlying mechanisms of dyslexia result from differences within the ...
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Neuroanatomy
Neuroanatomy is the study of the structure and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defined nervous systems. Their neuroanatomy is therefore better understood. In vertebrates, the nervous system is segregated into the internal structure of the brain and spinal cord (together called the central nervous system, or CNS) and the series of nerves that connect the CNS to the rest of the body (known as the peripheral nervous system, or PNS). Breaking down and identifying specific parts of the nervous system has been crucial for figuring out how it operates. For example, much of what neuroscientists have learned comes from observing how damage or "lesions" to specific brain areas affects behavior or other neural functions. For information about the composition of non-human animal nervous systems, see nervous system. For information a ...
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Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the National public health institutes, national public health agency of the United States. It is a Federal agencies of the United States, United States federal agency under the United States Department of Health and Human Services, Department of Health and Human Services (HHS), and is headquartered in Atlanta, Georgia. The CDC's current nominee for director is Susan Monarez. She became acting director on January 23, 2025, but stepped down on March 24, 2025 when nominated for the director position. On May 14, 2025, Robert F. Kennedy Jr. stated that lawyer Matthew Buzzelli is acting CDC director. However, the CDC web site does not state the acting director's name. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It e ...
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Diethylstilbestrol
Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is presently rarely used. In the past, it was widely used for a variety of indications, including pregnancy support for those with a history of recurrent miscarriage, hormone therapy for menopausal symptoms and estrogen deficiency, treatment of prostate cancer and breast cancer, and other uses. By 2007, it was only used in the treatment of prostate cancer and breast cancer. In 2011, Hoover and colleagues reported adverse reproductive health outcomes linked to DES including infertility, miscarriage, ectopic pregnancy, preeclampsia, preterm birth, stillbirth, infant death, menopause prior to age 45, breast cancer, cervical cancer, and vaginal cancer. While most commonly taken by mouth, DES was available for use by other routes as well, for instance, vaginal, topical, and by injection. DES is an estrogen, or an agonist of the estrogen receptors, the biologic ...
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Sex Differences In Humans
Sex differences in humans have been studied in a variety of fields. Sex determination generally occurs by the presence or absence of a Y chromosome in the 23rd pair of chromosomes in the human genome. '' Phenotypic sex'' refers to an individual's sex as determined by their internal and external genitalia and expression of secondary sex characteristics. Sex differences generally refer to traits that are sexually dimorphic. A subset of such differences is hypothesized to be the product of the evolutionary process of sexual selection.Mealey, L. (2000). ''Sex differences''. NY: Academic Press. Medicine Sex differences in medicine include sex-specific diseases, which are diseases that occur ''only'' in people of one sex; and sex-related diseases, which are diseases that are more usual to one sex, or which manifest differently in each sex. For example, certain autoimmune diseases may occur predominantly in one sex, for unknown reasons. 90% of primary biliary cirrhosis cases ...
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