|
Geriatric Onset Laryngeal Paralysis Polyneuropathy
Geriatric onset laryngeal paralysis polyneuropathy (GOLPP), previously described as idiopathic laryngeal paralysis (ILP), is a degenerative polyneuropathy that most commonly occurs in older medium-to-large breed dogs. Animals with this condition have historically tended to come to veterinary attention when they develop difficulties related to opening and closing the arytenoid cartilages of the larynx in the throat of the animal, causing difficulty with breathing and swallowing, and was therefore for many years the condition was believed to be an idiopathic form of laryngeal paralysis, meaning "of unknown cause". Investigations into idiopathic laryngeal paralysis by two groups (in Michigan and Tennessee) between 2005 and 2013 showed that dogs with ILP did not only suffer dysfunction of the laryngeal nerves; they found that this was just one prominent symptom of what was a very gradually progressing polyneuropathy of old age, which also affected other nerves in the body. This fin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Degenerative Disease
Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time. In neurodegenerative diseases, cells of the central nervous system stop working or die via neurodegeneration. An example of this is Alzheimer's disease. The other two common groups of degenerative diseases are those that affect circulatory system (e.g. coronary artery disease) and neoplastic diseases (e.g. cancers). Many degenerative diseases exist and some are related to aging. Normal bodily wear or lifestyle choices (such as exercise or eating habits) may worsen degenerative diseases, but this depends on the disease. Sometimes the main or partial cause behind such diseases is genetic. Thus some are clearly hereditary like Huntington's disease. Sometimes the cause is viruses, poisons or other chemicals. The cause may also be unknown. Some degenerative diseases can be cured, but not always. It might still be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyneuropathy
Polyneuropathy (poly- + neuro- + -pathy) is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain. It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, including diabetes and some types of Guillain–Barré syndrome. Classification Polyneuropathies may be classified in different ways, such as by ''cause'', by ''presentation'', or by ''classes'' of polyneuropathy, in terms of which part of the nerve cell is affected mainly: the axon, the myelin sheath, or the cell body. * ''Distal axonopathy'', is the result of interrupted function of the peripheral nerves. It is the most common response of neurons to metabolic or toxic disturbances, and may be caused by metabolic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arytenoid Cartilage
The arytenoid cartilages () are a pair of small three-sided pyramids which form part of the larynx. They are the site of attachment of the vocal cords. Each is pyramidal or ladle-shaped and has three surfaces, a base, and an apex. The arytenoid cartilages allow for movement of the vocal cords by articulating with the cricoid cartilage. It may be affected by arthritis, dislocations, or sclerosis. Structure The arytenoid cartilages are part of the posterior part of the larynx. Surfaces The posterior surface is triangular, smooth, concave, and gives attachment to the arytenoid muscle and transversus. The antero-lateral surface is somewhat convex and rough. On it, near the apex of the cartilage, is a rounded elevation (colliculus) from which a ridge (crista arcuata) curves at first backward and then downward and forward to the vocal process. The lower part of this crest intervenes between two depressions or foveæ, an upper, triangular, and a lower oblong in shape; the la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Larynx
The larynx (), commonly called the voice box, is an organ in the top of the neck involved in breathing, producing sound and protecting the trachea against food aspiration. The opening of larynx into pharynx known as the laryngeal inlet is about 4–5 centimeters in diameter. The larynx houses the vocal cords, and manipulates pitch and volume, which is essential for phonation. It is situated just below where the tract of the pharynx splits into the trachea and the esophagus. The word ʻlarynxʼ (plural ʻlaryngesʼ) comes from the Ancient Greek word ''lárunx'' ʻlarynx, gullet, throat.ʼ Structure The triangle-shaped larynx consists largely of cartilages that are attached to one another, and to surrounding structures, by muscles or by fibrous and elastic tissue components. The larynx is lined by a ciliated columnar epithelium except for the vocal folds. The cavity of the larynx extends from its triangle-shaped inlet, to the epiglottis, and to the circular outlet at t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Idiopathic
An idiopathic disease is any disease with an unknown cause or mechanism of apparent spontaneous origin. From Greek ἴδιος ''idios'' "one's own" and πάθος ''pathos'' "suffering", ''idiopathy'' means approximately "a disease of its own kind". For some medical conditions, one or more causes are somewhat understood, but in a certain percentage of people with the condition, the cause may not be readily apparent or characterized. In these cases, the origin of the condition is said to be idiopathic. With some other medical conditions, the root cause for a large percentage of all cases have not been established—for example, focal segmental glomerulosclerosis or ankylosing spondylitis; the majority of these cases are deemed idiopathic. Medical advances and this term Advances in medical science improve the understanding of causes of diseases and the classification of diseases; thus, regarding any particular condition or disease, as more root causes are discovered and as events t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laryngeal Paralysis
Laryngeal paralysis in animals is a condition in which the nerves and muscles that control the movements of one or both arytenoid cartilages of the larynx cease to function, and instead of opening during aspiration and closing during swallowing, the arytenoids remain stationary in a somewhat neutral position. Specifically, the muscle that causes abduction of the arytenoid cartilage, the cricoarytenoideus dorsalis muscle, ceases to function. This leads to inadequate ventilation during exercise and during thermoregulatory panting as well as incomplete protection of the airway during swallowing. One of the most common forms of laryngeal paralysis develops in aging in dogs, geriatric medium to large breed dogs, in particular the Labrador retriever, but also some other breeds. This had been traditionally known as idiopathic laryngeal paralysis ("ILP": idiopathic means "of unknown cause"), and was believed to be a result of a condition affecting the nerves of the larynx (bilateral monon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michigan
Michigan () is a U.S. state, state in the Great Lakes region, Great Lakes region of the Upper Midwest, upper Midwestern United States. With a population of nearly 10.12 million and an area of nearly , Michigan is the List of U.S. states and territories by population, 10th-largest state by population, the List of U.S. states and territories by area, 11th-largest by area, and the largest by area east of the Mississippi River.''i.e.'', including water that is part of state territory. Georgia (U.S. state), Georgia is the largest state by land area alone east of the Mississippi and Michigan the second-largest. Its capital is Lansing, Michigan, Lansing, and its largest city is Detroit. Metro Detroit is among the nation's most populous and largest metropolitan economies. Its name derives from a gallicization, gallicized variant of the original Ojibwe language, Ojibwe word (), meaning "large water" or "large lake". Michigan consists of two peninsulas. The Lower Peninsula of Michigan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tennessee
Tennessee ( , ), officially the State of Tennessee, is a landlocked state in the Southeastern region of the United States. Tennessee is the 36th-largest by area and the 15th-most populous of the 50 states. It is bordered by Kentucky to the north, Virginia to the northeast, North Carolina to the east, Georgia, Alabama, and Mississippi to the south, Arkansas to the southwest, and Missouri to the northwest. Tennessee is geographically, culturally, and legally divided into three Grand Divisions of East, Middle, and West Tennessee. Nashville is the state's capital and largest city, and anchors its largest metropolitan area. Other major cities include Memphis, Knoxville, Chattanooga, and Clarksville. Tennessee's population as of the 2020 United States census is approximately 6.9 million. Tennessee is rooted in the Watauga Association, a 1772 frontier pact generally regarded as the first constitutional government west of the Appalachian Mountains. Its name derives fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Afghan Hound
The Afghan Hound is a hound that is distinguished by its thick, fine, silky coat and its tail with a ring curl at the end. The breed is selectively bred for its unique features in the cold mountains of Afghanistan. Its local name is ( ps, تاژي سپی) or ( prs, سگ تازی). Other names for this breed are Tāzī, Balkh Hound, Baluchi Hound, Barakzai Hound, Shalgar Hound, Kabul Hound, Galanday Hound or sometimes incorrectly African Hound. They have the ability to run and turn well. History The Afghan Hound has been identified as a basal breed that predates the emergence of the modern breeds in the 19th century. It is most closely related to the Saluki. Connections with other types and breeds from the same area may provide clues to the history. A name for a desert coursing Afghan hound, Tazi (Sag-e-Tazi), suggests a shared ancestry with the very similar Tasy breed from the Caspian Sea area of Russia and Turkmenistan. Other types or breeds of similar appearance are the Tai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Golden Retriever
The Golden Retriever is a Scottish breed of retriever dog of medium size. It is characterised by a gentle and affectionate nature and a striking golden coat. It is commonly kept as a pet and is among the most frequently registered breeds in several Western countries. It is a frequent competitor in dog shows and obedience trials; it is also used as a gundog, and may be trained for use as a guide dog. The breed was created by Sir Dudley Marjoribanks at his Scottish estate Guisachan in the late nineteenth century. He cross-bred Flat-coated Retrievers with Tweed Water Spaniels, with some further infusions of Red Setter, Labrador Retriever and Bloodhound. The breed was recognised by the Kennel Club in 1913, and during the interwar period spread to many parts of the world. History The Golden Retriever was developed in Scotland in the nineteenth century by Sir Dudley Marjoribanks (later to become Baron Tweedmouth) from Flat-coated Retrievers judiciously crossed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Irish Setter
The Irish Setter ( ga, sotar rua, literally "red setter") is a setter, a breed of gundog, and family dog. The term ''Irish Setter'' is commonly used to encompass the show-bred dog recognised by the American Kennel Club as well as the field-bred Red Setter recognised by the Field Dog Stud Book. Description Appearance The coat is moderately long, silky, and of a red or chestnut colour. It requires frequent brushing to maintain its condition and keep it mat-free. The undercoat is abundant in winter weather, and the top coat is fine. Their coats should also feather in places such as the tail, ears, chest, legs, and body. Irish Setters range in height from , males weigh and females . The FCI Breed Standard for the Irish Setter stipulates males stand tall, and females be tall. Irish Setters are deep chested dogs with small waists. An Irish Setter's life expectancy tends to be around 11 to 12 years. Temperament Irish Setters get along well with children and other dogs and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
