Gene Silencing Pesticide
Gene silencing pesticides are pesticides that use gene silencing, and RNA interference (RNAi) in particular to target individual species while leaving other species unharmed.EOS magazine, June 2010 History In 1998, it was found that double-stranded RNA, injected to worms influenced the natural gene sequence in such a way that it was silenced. Equally surprising was that the genes were also silenced when the worms ingested the dsRNA. Steven Whyard, working for CSIRO Entomology at that time, then also tried it with insects. To his surprise, this also worked, and they just invented something that had huge implications. They then patented the technology and by 2006, it was used in pesticides. Two articles were then also published that confirmed that the effect was powerful enough to protect plants from pests. Examples * Monsanto and Devgen developed a gene silencing pesticide against ''Diabrotica virgifera'' * A team, led by Xiao-Ya Chen fed gossypol with dsRNA targeting the gene fo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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RNAi
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by other names, including ''co-suppression'', ''post-transcriptional gene silencing'' (PTGS), and ''quelling''. The detailed study of each of these seemingly different processes elucidated that the identity of these phenomena were all actually RNAi. Andrew Fire and Craig Mello shared the 2006 Nobel Prize in Physiology or Medicine for their work on RNAi in the nematode worm '' Caenorhabditis elegans'', which they published in 1998. Since the discovery of RNAi and its regulatory potentials, it has become evident that RNAi has immense potential in suppression of desired genes. RNAi is now known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vect ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gene Silencing
Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. Gene silencing can occur during either Transcription (genetics), transcription or Translation (biology), translation and is often used in research. In particular, methods used to silence genes are being increasingly used to produce therapeutics to combat cancer and other diseases, such as infectious diseases and neurodegenerative disorders. Gene silencing is often considered the same as gene knockdown. When genes are silenced, their expression is reduced. In contrast, when genes are knocked out, they are completely erased from the organism's genome and, thus, have no expression. Gene silencing is considered a gene knockdown mechanism since the methods used to silence genes, such as RNAi, CRISPR, or siRNA, generally reduce the expression of a gene by at least 70% but do not eliminate it. Methods using gene silencing are often considered better than gene knockouts since they allo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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RNA Interference
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by other names, including ''co-suppression'', ''post-transcriptional gene silencing'' (PTGS), and ''quelling''. The detailed study of each of these seemingly different processes elucidated that the identity of these phenomena were all actually RNAi. Andrew Fire and Craig Mello shared the 2006 Nobel Prize in Physiology or Medicine for their work on RNAi in the nematode worm ''Caenorhabditis elegans'', which they published in 1998. Since the discovery of RNAi and its regulatory potentials, it has become evident that RNAi has immense potential in suppression of desired genes. RNAi is now known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vector may be ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Steven Whyard
Stephen or Steven is an English first name. It is particularly significant to Christians, as it belonged to Saint Stephen ( ), an early disciple and deacon who, according to the Book of Acts, was stoned to death; he is widely regarded as the first martyr (or "protomartyr") of the Christian Church. The name, in both the forms Stephen and Steven, is often shortened to Steve or Stevie. In English, the female version of the name is Stephanie. Many surnames are derived from the first name, including Stephens, Stevens, Stephenson, and Stevenson, all of which mean "Stephen's (son)". In modern times the name has sometimes been given with intentionally non-standard spelling, such as Stevan or Stevon. A common variant of the name used in English is Stephan ( ); related names that have found some currency or significance in English include Stefan (pronounced or in English), Esteban (often pronounced ), and the Shakespearean Stephano ( ). Origins The name "Stephen" (and its comm ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Diabrotica Virgifera
''Diabrotica virgifera'' is a species of beetle in the family Chrysomelidae. It is an agricultural pest species that attacks maize Maize (; ''Zea mays''), also known as corn in North American English, is a tall stout grass that produces cereal grain. It was domesticated by indigenous peoples in southern Mexico about 9,000 years ago from wild teosinte. Native American .... It includes two subspecies, '' Diabrotica virgifera virgifera'' (the western corn rootworm) and '' Diabrotica virgifera zeae'' (the Mexican corn rootworm). References Galerucinae Beetles described in 1868 Taxa named by John Lawrence LeConte {{Galerucinae-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bollworm
Bollworm is the common term for a moth larva that attacks the fruiting bodies of certain crops, especially cotton. The most common moths known as bollworms are: * Red or Sudan bollworm, '' Diparopsis castanea'' * Rough bollworm, '' Earias perhuegeli'' * Spotted bollworm, '' Earias fabia'' * Spiny bollworm, '' Earias insulana'' * Spotted bollworm, '' Earias vittella'' * American cotton bollworm or tomato grub, ''Helicoverpa armigera'' * Cotton bollworm, ''Helicoverpa gelotopoeon'' * Cotton bollworm, ''Helicoverpa punctigera'' * Corn earworm, ''Helicoverpa zea'' * Tobacco budworm, ''Heliothis virescens'' * Pink bollworm, '' Pectinophora gossypiella'' * Pinkspotted bollworm, '' Pectinophora scutigera'' See also * Cotton bollworm *Boll weevil The boll weevil (''Anthonomus grandis'') is a species of beetle in the family Curculionidae. The boll weevil feeds on cotton buds and flowers. Thought to be native to Central Mexico, it migrated into the United States from Mexico in the late ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Colorado Beetle
The Colorado potato beetle (''Leptinotarsa decemlineata''; also known as the Colorado beetle, the ten-striped spearman, the ten-lined potato beetle, and the potato bug) is a beetle known for being a major pest of potato crops. It is about long, with a bright yellow/orange body and five bold brown stripes along the length of each of its wings. Native to the Rocky Mountains, it spread rapidly in potato crops across America and then Europe from 1859 onwards.see pp. 453–454: "Doryphora, Illig.: D. 10-lineata"./ref> The Colorado potato beetle was first observed in 1811 by Thomas Nuttall and was formally described in 1824 by American entomologist Thomas Say. The beetles were collected in the Rocky Mountains, where they were feeding on the buffalo bur, '' Solanum rostratum''. Description Adult beetles typically are in length and in width. They weigh 50–170 mg. The beetles are orange-yellow in color with 10 characteristic black stripes on their front wings or elytra. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Michael Scharf
Michael P. Scharf (born April 25, 1963 in Pittsburgh, PA) is co-dean, Joseph C. Hostetler – BakerHostetler professor of law, and the director of the Frederick K. Cox International Law Center at Case Western Reserve University School of Law. Scharf is also co-founder of the Public International Law & Policy Group (PILPG), a non-governmental organization (NGO) which provides pro bono legal assistance to developing states and states in transition. Since 1995 PILPG has provided pro bono legal assistance to states and governments involved in peace negotiations, drafting post-conflict constitutions, and prosecuting war criminals. Since March 2012, Scharf has also been the producer and host of ''Talking Foreign Policy'', a one-hour radio program aired on a quarterly basis on Cleveland’s NPR affiliate WCPN 90.3 ideastream. Career On February 14, 2022, Michael Scharf presented an oral argument before the Appeals Chamber of the International Criminal Court in The Hague concerning ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Plant Toxin Insecticides
Plants are the eukaryotes that form the kingdom Plantae; they are predominantly photosynthetic. This means that they obtain their energy from sunlight, using chloroplasts derived from endosymbiosis with cyanobacteria to produce sugars from carbon dioxide and water, using the green pigment chlorophyll. Exceptions are parasitic plants that have lost the genes for chlorophyll and photosynthesis, and obtain their energy from other plants or fungi. Most plants are multicellular, except for some green algae. Historically, as in Aristotle's biology, the plant kingdom encompassed all living things that were not animals, and included algae and fungi. Definitions have narrowed since then; current definitions exclude fungi and some of the algae. By the definition used in this article, plants form the clade Viridiplantae (green plants), which consists of the green algae and the embryophytes or land plants ( hornworts, liverworts, mosses, lycophytes, ferns, conifers and other gymno ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |