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Functional Ultrasound Imaging
Functional ultrasound imaging (fUS) is a medical Medical ultrasound, ultrasound imaging technique for detecting or measuring changes in neural activities or metabolism, such as brain activity loci, typically through measuring Hemodynamics, hemodynamic (blood flow) changes. It is an extension of Doppler ultrasonography. Background Brain activation can be directly measured by imaging electrical activity of neurons using Voltage-sensitive dye, voltage-sensitive dyes, calcium imaging, Electroencephalography functional magnetic resonance imaging, electroencephalography, or magnetoencephalography. It can also be indirectly measured hemodynamically, that is, by detecting changes in blood flow in the neurovascular systems through functional magnetic resonance imaging (fMRI), positron emission tomography (PET), Functional near-infrared spectroscopy (fNIRS), or Doppler ultrasonography, etc. Optics-based methods generally provide the highest spatial and temporal resolutions; however, d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Main Applications And Features Of Functional Ultrasound (fUS) Imaging
Main may refer to: Geography *Main River (other), multiple rivers with the same name *Ma'in, an ancient kingdom in modern-day Yemen *Main, Iran, a village in Fars Province *Spanish Main, the Caribbean coasts of mainland Spanish territories in the 16th and 17th centuries *''The Main'', the diverse core running through Montreal, Quebec, Canada, also separating the Two Solitudes *Main (lunar crater), located near the north pole of the Moon *Main (Martian crater) People and organizations *Main (surname), a list of people with this family name *Main, alternate spelling for the Minaeans, an ancient people of modern-day Yemen *Main (band), a British ambient band formed in 1991 *Chas. T. Main, an American engineering and hydroelectric company founded in 1893 *MAIN (Mountain Area Information Network), former operator of WPVM-LP (MAIN-FM) in Asheville, North Carolina, U.S. *Main Deli Steak House ("The Main"), a smoked-meat delicatessen in Montreal, Quebec, Canada Ships *Main ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signal-to-noise Ratio
Signal-to-noise ratio (SNR or S/N) is a measure used in science and engineering that compares the level of a desired signal to the level of background noise. SNR is defined as the ratio of signal power to noise power, often expressed in decibels. A ratio higher than 1:1 (greater than 0 dB) indicates more signal than noise. SNR is an important parameter that affects the performance and quality of systems that process or transmit signals, such as communication systems, audio systems, radar systems, imaging systems, and data acquisition systems. A high SNR means that the signal is clear and easy to detect or interpret, while a low SNR means that the signal is corrupted or obscured by noise and may be difficult to distinguish or recover. SNR can be improved by various methods, such as increasing the signal strength, reducing the noise level, filtering out unwanted noise, or using error correction techniques. SNR also determines the maximum possible amount of data that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infant
In common terminology, a baby is the very young offspring of adult human beings, while infant (from the Latin word ''infans'', meaning 'baby' or 'child') is a formal or specialised synonym. The terms may also be used to refer to juveniles of other organisms. A newborn is, in colloquial use, a baby who is only hours, days, or weeks old; while in medical contexts, a newborn or neonate (from Latin, ''neonatus'', newborn) is an infant in the first 28 days after birth (the term applies to premature, full term, and postmature infants). Infants born prior to 37 weeks of gestation are called "premature", those born between 39 and 40 weeks are "full term", those born through 41 weeks are "late term", and anything beyond 42 weeks is considered "post term". Before birth, the offspring is called a fetus. The term ''infant'' is typically applied to very young children under one year of age; however, definitions may vary and may include children up to two years of age. When a human chi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Neuroimaging Using Ultrasound
Clinical may refer to: Healthcare * Of or about a clinic, a healthcare facility * Of or about the practice of medicine Other uses * ''Clinical'' (film), a 2017 American horror thriller See also * * * Clinical chemistry, the analysis of bodily fluids for diagnostic and therapeutic purposes * Clinical death, the cessation of blood circulation and breathing * Clinical formulation, a theoretically-based explanation of information obtained from clinical assessment * Clinical governance, a systematic approach to maintaining and improving the quality of patient care * Clinical linguistics, linguistics applied to speech-language pathology * Clinical psychology, the understanding, preventing, and relieving psychologically-based distress or dysfunction * Clinical research, to determine the safety and effectiveness of medications etc. * Clinical significance, the practical importance of a treatment effect * Clinical trial, experiments or observations done in clinical research * Clinical w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preclinical Applications Of FUS Imaging
In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals. The main goals of preclinical studies are to determine a starting, safe dose for first-in-human study and assess potential toxicity of the product, which typically include new medical devices, prescription drugs, and diagnostics. Companies use stylized statistics to illustrate the risks in preclinical research, such as that on average, only one in every 5,000 compounds that enters drug discovery to the stage of preclinical development becomes an approved drug. Types Each class of product may undergo different types of preclinical research. For instance, drugs may undergo pharmacodynamics (what the drug does to the body) (PD), pharmacokinetics (what the body does to th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tonotopy
In physiology, tonotopy (from Greek tono = frequency and topos = place) is the spatial arrangement of where sounds of different frequency are processed in the brain. Tones close to each other in terms of frequency are represented in topologically neighbouring regions in the brain. Tonotopic maps are a particular case of topographic organization, similar to retinotopy in the visual system. Tonotopy in the auditory system begins at the cochlea, the small snail-like structure in the inner ear that sends information about sound to the brain. Different regions of the basilar membrane in the organ of Corti, the sound-sensitive portion of the cochlea, vibrate at different sinusoidal frequencies due to variations in thickness and width along the length of the membrane. Nerves that transmit information from different regions of the basilar membrane therefore encode frequency tonotopically. This tonotopy then projects through the vestibulocochlear nerve and associated midbrain structures ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Functional Connectivity
Resting state fMRI (rs-fMRI or R-fMRI), also referred to as task-independent fMRI or task-free fMRI, is a method of functional magnetic resonance imaging (fMRI) that is used in brain mapping to evaluate regional interactions that occur in a resting or task-negative state, when an explicit task is not being performed. A number of resting-state brain networks have been identified, one of which is the default mode network. These brain networks are observed through changes in blood flow in the brain which creates what is referred to as a blood-oxygen-level dependent (BOLD) signal that can be measured using fMRI. Because brain activity is intrinsic, present even in the absence of an externally prompted task, any brain region will have spontaneous fluctuations in BOLD signal. The resting state approach is useful to explore the brain's functional organization and to examine if it is altered in neurological or mental disorders. Because of the resting state aspect of this imaging, dat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Primate
Primates is an order (biology), order of mammals, which is further divided into the Strepsirrhini, strepsirrhines, which include lemurs, galagos, and Lorisidae, lorisids; and the Haplorhini, haplorhines, which include Tarsiiformes, tarsiers and simians (monkeys and apes). Primates arose 74–63 million years ago first from small terrestrial animal, terrestrial mammals, which adapted for life in tropical forests: many primate characteristics represent adaptations to the challenging environment among Canopy (biology), tree tops, including large brain sizes, binocular vision, color vision, Animal communication, vocalizations, shoulder girdles allowing a large degree of movement in the upper limbs, and opposable thumbs (in most but not all) that enable better grasping and dexterity. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ferret
The ferret (''Mustela furo'') is a small, domesticated species belonging to the family Mustelidae. The ferret is most likely a domesticated form of the wild European polecat (''Mustela putorius''), as evidenced by the ferret's ability to interbreed with European polecats and produce hybrid offspring. Physically, ferrets resemble other mustelids because of their long, slender bodies. Including their tail, the average length of a ferret is about ; they weigh between ; and their fur can be black, brown, white, or a mixture of those colours. The species is sexually dimorphic, with males being considerably larger than females. Ferrets may have been domesticated since ancient times, but there is widespread disagreement because of the sparseness of written accounts and the inconsistency of those which survive. Contemporary scholarship agrees that ferrets were bred for sport, hunting rabbits in a practice known as rabbiting. In North America, the ferret has become an increasingly pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angiography
Angiography or arteriography is a medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers. Modern angiography is performed by injecting a radio-opaque contrast agent into the blood vessel and imaging using X-ray based techniques such as fluoroscopy. With time-of-flight (TOF) magnetic resonance it is no longer necessary to use a contrast. The word itself comes from the Greek words ἀνγεῖον ''angeion'' 'vessel' and γράφειν ''graphein'' 'to write, record'. The film or image of the blood vessels is called an ''angiograph'', or more commonly an ''angiogram''. Though the word can describe both an arteriogram and a venogram, in everyday usage the terms angiogram and arteriogram are often used synonymously, whereas the term venogram is used more precisely. The term angiography has been applied to radionuclide angiography and newer vascular ima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beamforming
Beamforming or spatial filtering is a signal processing technique used in sensor arrays for directional signal transmission or reception. This is achieved by combining elements in an antenna array in such a way that signals at particular angles experience constructive interference while others experience destructive interference. Beamforming can be used at both the transmitting and receiving ends in order to achieve spatial selectivity. The improvement compared with omnidirectional reception/transmission is known as the directivity of the array. Beamforming can be used for radio or sound waves. It has found numerous applications in radar, sonar, seismology, wireless communications, radio astronomy, acoustics and biomedicine. Adaptive beamforming is used to detect and estimate the signal of interest at the output of a sensor array by means of optimal (e.g. least-squares) spatial filtering and interference rejection. Techniques To change the directionality of the array when ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ESPCI
ESPCI Paris (officially the École supérieure de physique et de chimie industrielles de la ville de Paris, , ''The City of Paris Industrial Physics and Chemistry Higher Educational Institution'') is a grande école founded in 1882 by the city of Paris, France. It educates undergraduate and graduate students in physics, chemistry and biology and conducts high-level research in those fields. It is ranked as the first French ''École d'Ingénieurs'' in the 2017 Shanghai Ranking. ESPCI Paris is a constituent college of Université PSL and a founding member of the ParisTech (Paris Institute of Technology) alliance. Two thirds of the students enter the school following a competitive examination (concours X-ESPCI- ENS) following at least two years of Classes Préparatoires. The other students are recruited by submitting applications. The school itself is also known as Physique-Chimie or simply PC. ESPCI Paris nurtures relationships with many industrial partners such as Schlumberger, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
