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Frank's Sign
Frank's sign is a diagonal crease in the ear lobe extending from the tragus across the lobule to the rear edge of the auricle. The sign is named after Sanders T. Frank. It has been hypothesised that Frank's sign is indicative of cardiovascular disease and/or diabetes. Some studies have described Frank's sign as a marker of cardiovascular disease but not linked to the severity of the condition. In contrast, other studies have rebutted any association between Frank's sign and coronary artery disease in diabetics. There have also been reported cases of Frank's sign being a predictor of cerebral infarctions. A link between Frank's sign and premature aging and the loss of dermal and vascular fibers has also been hypothesized. Some studies have focused on association between bilateral earlobe crease and coronary artery disease. It is probably prudent to consider Frank's Sign alongside other clinical markers of physiological ageing, rather than utilising it as a stand-alone sign in t ...
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Blood Vessel
Blood vessels are the tubular structures of a circulatory system that transport blood throughout many Animal, animals’ bodies. Blood vessels transport blood cells, nutrients, and oxygen to most of the Tissue (biology), tissues of a Body (biology), body. They also take waste and carbon dioxide away from the tissues. Some tissues such as cartilage, epithelium, and the lens (anatomy), lens and cornea of the eye are not supplied with blood vessels and are termed ''avascular''. There are five types of blood vessels: the arteries, which carry the blood away from the heart; the arterioles; the capillaries, where the exchange of water and chemicals between the blood and the tissues occurs; the venules; and the veins, which carry blood from the capillaries back towards the heart. The word ''vascular'', is derived from the Latin ''vas'', meaning ''vessel'', and is mostly used in relation to blood vessels. Etymology * artery – late Middle English; from Latin ''arteria'', from Gree ...
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KDWN
K268CS (101.5 FM broadcasting, FM) is a Translator Radio broadcasting#Stations, radio station in Las Vegas, Las Vegas, Nevada, owned and operated by Audacy, Inc. The station pronounced its call sign, call letters as "K-Dawn". The station's studios were located in the unincorporated Clark County, Nevada, Clark County area of Spring Valley, Nevada, Spring Valley. Programming was also heard on 250-watt FM radio, FM Broadcast relay station, translator station K268CS on 101.5 Hertz, MHz. KDWN aired a talk radio, talk radio format. It ran several Radio syndication, nationally syndicated Conservative talk radio, conservative talk hosts, along with local shows, most of which were brokered programming. National hosts included Brian Kilmeade, Sean Hannity and Mark Levin. Other hours were devoted to money, health, real estate and sports. In most cases, the local hosts paid for their time on the air and were permitted to run their own advertising. Most hours on weekdays began with world and ...
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Mel Gibson
Mel Columcille Gerard Gibson (born January 3, 1956) is an American actor and filmmaker. The recipient of List of awards and nominations received by Mel Gibson, multiple accolades, he is known for directing historical films as well for his action hero roles, particularly his breakout role as Max Rockatansky in the first three films of the Apocalyptic and post-apocalyptic fiction, post-apocalyptic series ''Mad Max'' (1979–1985) and as Martin Riggs in the buddy cop film, buddy cop series ''Lethal Weapon (franchise), Lethal Weapon'' (1987–1998). Born in Peekskill, New York, Gibson moved with his parents to Sydney, Australia, when he was 12 years old. He studied acting at the National Institute of Dramatic Art, where he starred opposite Judy Davis in a production of ''Romeo and Juliet''. During the 1980s, he founded Icon Entertainment, a production company. Director Peter Weir cast him as one of the leads in the World War I drama ''Gallipoli (1981 film), Gallipoli'' (1981), whi ...
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Metro (British Newspaper)
''Metro'' is a British freesheet tabloid newspaper published by DMG Media. The newspaper is distributed from Monday to Friday mornings on public places in areas of England, Wales and Scotland (excluding public holidays and the period between Christmas Eve and New Year's Day inclusive). Copies are also handed out to pedestrians. In 2018, Metro overtook ''The Sun'' to become the most circulated newspaper in the United Kingdom. ''Metro'' is owned by Daily Mail and General Trust plc (DMGT), part of the same media group as the ''Daily Mail'' and ''The Mail on Sunday'', but in some areas ''Metro'' operates as a franchise with a local newspaper publisher, rather than as a wholly owned concern. While being a sister paper to the conservative ''Daily Mail'', the newspaper has never endorsed any political party or candidate, and says it takes a neutral political stance in its reporting.
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George W
George Walker Bush (born July 6, 1946) is an American politician and businessman who was the 43rd president of the United States from 2001 to 2009. A member of the Bush family and the Republican Party (United States), Republican Party, he is the eldest son of the 41st president, George H. W. Bush, and was the 46th governor of Texas from 1995 to 2000. Bush flew warplanes in the Texas Air National Guard in his twenties. After graduating from Harvard Business School in 1975, he worked in the oil industry. He later co-owned the Major League Baseball team Texas Rangers (baseball), Texas Rangers before being elected governor of Texas 1994 Texas gubernatorial election, in 1994. Governorship of George W. Bush, As governor, Bush successfully sponsored legislation for tort reform, increased education funding, set higher standards for schools, and reformed the criminal justice system. He also helped make Texas the Wind power in Texas, leading producer of wind-generated electricity in t ...
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Dick Van Dyke
Richard Wayne Van Dyke (born December 13, 1925) is an American actor, entertainer and comedian. Dick Van Dyke on screen and stage, His work spans screen and stage, and List of awards and nominations received by Dick Van Dyke, his awards include six Emmy Awards, a Grammy Award and a Tony Award. He was inducted into the Television Hall of Fame in 1995 and the Hollywood Walk of Fame in 1993, and has been honored with the Screen Actors Guild Life Achievement Award in 2013, the Kennedy Center Honors in 2020, and was recognized as a Disney Legend in 1998. Van Dyke began his career as an entertainer on radio, television and in nightclubs. He made his Broadway theatre, Broadway debut in the musical revue ''The Girls Against the Boys'' (1959). The following year he starred as Albert F. Peterson in the original production of ''Bye Bye Birdie'' (1960), a role which earned him the Tony Award for Best Featured Actor in a Musical. He returned to Broadway playing Harold Hill in a revival of ' ...
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Ageing
Ageing (or aging in American English) is the process of becoming older until death. The term refers mainly to humans, many other animals, and fungi; whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species. In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes. Reaction time, for example, may slow with age, while memories and general knowledge typically increase. Of the roughly 150,000 people who die each day across the globe, about two-thirds die from age-related causes. Current ageing theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the programmed ageing concept, whereby the internal processes (e ...
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Coronary Artery Disease
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of cardiovascular disease, heart disease involving Ischemia, the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the Coronary arteries, arteries of the heart. It is the most common of the cardiovascular diseases. CAD can cause stable angina, unstable angina, myocardial ischemia, and myocardial infarction. A common symptom is angina, which is chest pain or discomfort that may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. In stable angina, symptoms occur with exercise or emotional Psychological stress, stress, last less than a few minutes, and improve with rest. Shortness of breath may also occur and sometimes no symptoms are present. In many cases, the first sign is a Myocardial infarction, heart attack. Other complications include heart failure or an Heart arrhythmia, abnormal h ...
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Elastic Fiber
Elastic fibers (or yellow fibers) are an essential component of the extracellular matrix composed of bundles of proteins (elastin) which are produced by a number of different cell types including fibroblasts, endothelial, smooth muscle, and airway epithelial cells. These fibers are able to stretch many times their length, and snap back to their original length when relaxed without loss of energy. Elastic fibers include elastin, elaunin and oxytalan. Elastic fibers are formed via elastogenesis, a highly complex process involving several key proteins including fibulin-4, fibulin-5, latent transforming growth factor β binding protein 4, and microfibril associated protein 4. In this process tropoelastin, the soluble monomeric precursor to elastic fibers is produced by elastogenic cells and chaperoned to the cell surface. Following excretion from the cell, tropoelastin self associates into ~200 nm particles by coacervation, an entropically driven process involving interact ...
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Dermis
The dermis or corium is a layer of skin between the epidermis (skin), epidermis (with which it makes up the cutis (anatomy), cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain. It is divided into two layers, the superficial area adjacent to the epidermis called the papillary region and a deep thicker area known as the reticular dermis.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology'' (10th ed.). Saunders. Pages 1, 11–12. . The dermis is tightly connected to the epidermis through a basement membrane. Structural components of the dermis are collagen, elastic fibers, and Ground substance, extrafibrillar matrix.Marks, James G; Miller, Jeffery (2006). ''Lookingbill and Marks' Principles of Dermatology'' (4th ed.). Elsevier Inc. Page 8–9. . It also contains mechanoreceptors that provide the sense of touch and thermoreceptors that provide ...
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Frank S Sign
Frank, FRANK, or Franks may refer to: People * Frank (given name) * Frank (surname) * Franks (surname) * Franks, a Germanic people in late Roman times * Franks, a term in the Muslim world for all western Europeans, particularly during the Crusades Currency * Liechtenstein franc or frank, the currency of Liechtenstein since 1920 * Swiss franc or frank, the currency of Switzerland since 1850 * Westphalian frank, currency of the Kingdom of Westphalia between 1808 and 1813 * The currencies of the German-speaking cantons of Switzerland (1803–1814): ** Appenzell frank ** Aargau frank ** Basel frank ** Berne frank ** Fribourg frank ** Glarus frank ** Graubünden frank ** Luzern frank ** Schaffhausen frank ** Schwyz frank ** Solothurn frank ** St. Gallen frank ** Thurgau frank ** Unterwalden frank ** Uri frank ** Zürich frank Places * Frank, Alberta, Canada, an urban community, formerly a village * Franks, Illinois, United States, an unincorporated community * Franks, Mis ...
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