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Folding@home
Folding@home (FAH or F@h) is a distributed computing project aimed to help scientists develop new therapeutics for a variety of diseases by the means of simulating protein dynamics. This includes the process of protein folding and the movements of proteins, and is reliant on simulations run on volunteers' personal computers. Folding@home is currently based at the University of Pennsylvania and led by Greg Bowman, a former student of Vijay S. Pande, Vijay Pande. The project utilizes graphics processing units (GPUs), central processing units (CPUs), and ARM architecture, ARM processors like those on the Raspberry Pi for distributed computing and scientific research. The project uses statistical simulation methodology that is a paradigm shift from traditional computing methods. As part of the client–server model network architecture, the volunteered machines each receive pieces of a simulation (work units), complete them, and return them to the project's database servers, where th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sony
is a Japanese multinational conglomerate (company), conglomerate headquartered at Sony City in Minato, Tokyo, Japan. The Sony Group encompasses various businesses, including Sony Corporation (electronics), Sony Semiconductor Solutions (imaging and sensing), Sony Entertainment (including Sony Pictures and Sony Music Group), Sony Interactive Entertainment (video games), Sony Financial Group, and others. Sony was founded in 1946 as by Masaru Ibuka and Akio Morita. In 1958, the company adopted the name Initially an electronics firm, it gained early recognition for products such as the TR-55 transistor radio and the CV-2000 home video tape recorder, contributing significantly to Japan's Japanese economic miracle, post-war economic recovery. After Ibuka's retirement in the 1970s, Morita served as chairman until 1994, overseeing Sony's rise as a global brand recognized for innovation in consumer electronics. Landmark products included the Trinitron color television, the Walkma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Personal Computer
A personal computer, commonly referred to as PC or computer, is a computer designed for individual use. It is typically used for tasks such as Word processor, word processing, web browser, internet browsing, email, multimedia playback, and PC game, gaming. Personal computers are intended to be operated directly by an end user, rather than by a computer expert or technician. Unlike large, costly minicomputers and mainframes, time-sharing by many people at the same time is not used with personal computers. The term home computer has also been used, primarily in the late 1970s and 1980s. The advent of personal computers and the concurrent Digital Revolution have significantly affected the lives of people. Institutional or corporate computer owners in the 1960s had to write their own programs to do any useful work with computers. While personal computer users may develop their applications, usually these systems run commercial software, free-of-charge software ("freeware"), which i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic
The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December 2019. Soon after, it spread to other areas of Asia, and COVID-19 pandemic by country and territory, then worldwide in early 2020. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern (PHEIC) on 30 January 2020, and assessed the outbreak as having become a pandemic on 11 March. COVID-19 symptoms range from asymptomatic to deadly, but most commonly include fever, sore throat, nocturnal cough, and fatigue. Transmission of COVID-19, Transmission of the virus is often airborne transmission, through airborne particles. Mutations have variants of SARS-CoV-2, produced many strains (variants) with varying degrees of infectivity and virulence. COVID-19 vaccines were developed rapidly and deplo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Database Server
A database server is a server which uses a database application that provides database services to other computer programs or to computers, as defined by the client–server model. Database management systems (DBMSs) frequently provide database-server functionality, and some database management systems (such as MySQL) rely exclusively on the client–server model for database access (while others, like SQLite, are meant for use as an embedded database). Users access a database server either through a " front end" running on the user's computerwhich displays requested dataor through the " back end", which runs on the server and handles tasks such as data analysis and storage. In a master–slave model, database master servers are central and primary locations of data while database slave servers are synchronized backups of the master acting as proxies. Most database applications respond to a query language. Each database understands its query language and converts each submi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Network Architecture
Network architecture is the design of a computer network. It is a framework for the specification of a network's physical components and their functional organization and configuration, its operational principles and procedures, as well as communication protocols used. In telecommunications, the specification of a network architecture may also include a detailed description of products and services delivered via a communications network, as well as detailed rate and billing structures under which services are compensated. The network architecture of the Internet is predominantly expressed by its use of the Internet protocol suite, rather than a specific model for interconnecting networks or nodes in the network, or the usage of specific types of hardware links. OSI model The Open Systems Interconnection model (OSI model) defines and codifies the concept of layered network architecture. Abstraction layers are used to subdivide a communications system further into smaller man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Client–server Model
The client–server model is a distributed application structure that partitions tasks or workloads between the providers of a resource or service, called servers, and service requesters, called clients. Often clients and servers communicate over a computer network on separate hardware, but both client and server may be on the same device. A server host runs one or more server programs, which share their resources with clients. A client usually does not share its computing resources, but it requests content or service from a server and may share its own content as part of the request. Clients, therefore, initiate communication sessions with servers, which await incoming requests. Examples of computer applications that use the client–server model are email, network printing, and the World Wide Web. Client and server role The server component provides a function or service to one or many clients, which initiate requests for such services. Servers are classified by the servic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paradigm Shift
A paradigm shift is a fundamental change in the basic concepts and experimental practices of a scientific discipline. It is a concept in the philosophy of science that was introduced and brought into the common lexicon by the American physicist and philosopher Thomas Kuhn. Even though Kuhn restricted the use of the term to the natural sciences, the concept of a paradigm shift has also been used in numerous non-scientific contexts to describe a profound change in a fundamental model or perception of events. Kuhn presented his notion of a paradigm shift in his influential book ''The Structure of Scientific Revolutions'' (1962). Kuhn contrasts paradigm shifts, which characterize a Scientific Revolution, to the activity of normal science, which he describes as scientific work done within a prevailing framework or paradigm. Paradigm shifts arise when the dominant paradigm under which normal science operates is rendered incompatible with new phenomena, facilitating the adoption of a ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Simulation
A simulation is an imitative representation of a process or system that could exist in the real world. In this broad sense, simulation can often be used interchangeably with model. Sometimes a clear distinction between the two terms is made, in which simulations require the use of models; the model represents the key characteristics or behaviors of the selected system or process, whereas the simulation represents the evolution of the model over time. Another way to distinguish between the terms is to define simulation as experimentation with the help of a model. This definition includes time-independent simulations. Often, computer simulation, computers are used to execute the simulation. Simulation is used in many contexts, such as simulation of technology for performance tuning or optimizing, safety engineering, testing, training, education, and video games. Simulation is also used with scientific modelling of natural systems or human systems to gain insight into their functio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Raspberry Pi
Raspberry Pi ( ) is a series of small single-board computers (SBCs) developed in the United Kingdom by the Raspberry Pi Foundation in collaboration with Broadcom Inc., Broadcom. To commercialize the product and support its growing demand, the Foundation established a commercial entity, Raspberry Pi Holdings, a public company that trades on the London Stock Exchange. The Raspberry Pi was originally created to help teach computer science in schools, but gained popularity for many other uses due to its low cost, compact size, and flexibility. It is now used in areas such as Industrial Automation and Control Systems, industrial automation, robotics, home automation, IoT devices, and hobbyist projects. The company's products range from simple microcontrollers to computers that the company markets as being powerful enough to be used as a general purpose PC. Computers are built around a custom designed system on a chip and offer features such as HDMI video/audio output, USB ports, wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ARM Architecture
ARM (stylised in lowercase as arm, formerly an acronym for Advanced RISC Machines and originally Acorn RISC Machine) is a family of reduced instruction set computer, RISC instruction set architectures (ISAs) for central processing unit, computer processors. Arm Holdings develops the ISAs and licenses them to other companies, who build the physical devices that use the instruction set. It also designs and licenses semiconductor intellectual property core, cores that implement these ISAs. Due to their low costs, low power consumption, and low heat generation, ARM processors are useful for light, portable, battery-powered devices, including smartphones, laptops, and tablet computers, as well as embedded systems. However, ARM processors are also used for desktop computer, desktops and server (computing), servers, including Fugaku (supercomputer), Fugaku, the world's fastest supercomputer from 2020 to 2022. With over 230 billion ARM chips produced, , ARM is the most widely used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Processing Unit
A central processing unit (CPU), also called a central processor, main processor, or just processor, is the primary Processor (computing), processor in a given computer. Its electronic circuitry executes Instruction (computing), instructions of a computer program, such as arithmetic, logic, controlling, and input/output (I/O) operations. This role contrasts with that of external components, such as main memory and I/O circuitry, and specialized coprocessors such as graphics processing units (GPUs). The form, CPU design, design, and implementation of CPUs have changed over time, but their fundamental operation remains almost unchanged. Principal components of a CPU include the arithmetic–logic unit (ALU) that performs arithmetic operation, arithmetic and Bitwise operation, logic operations, processor registers that supply operands to the ALU and store the results of ALU operations, and a control unit that orchestrates the #Fetch, fetching (from memory), #Decode, decoding and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Graphics Processing Unit
A graphics processing unit (GPU) is a specialized electronic circuit designed for digital image processing and to accelerate computer graphics, being present either as a discrete video card or embedded on motherboards, mobile phones, personal computers, workstations, and game consoles. GPUs were later found to be useful for non-graphic calculations involving embarrassingly parallel problems due to their parallel structure. The ability of GPUs to rapidly perform vast numbers of calculations has led to their adoption in diverse fields including artificial intelligence (AI) where they excel at handling data-intensive and computationally demanding tasks. Other non-graphical uses include the training of neural networks and cryptocurrency mining. History 1970s Arcade system boards have used specialized graphics circuits since the 1970s. In early video game hardware, RAM for frame buffers was expensive, so video chips composited data together as the display was being scann ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
