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Euphorbia Resinifera
''Euphorbia resinifera'', the resin spurge, is a species of spurge native to Morocco, where it occurs on the slopes of the Atlas Mountains. The dried latex of the plant was used in ancient medicine. It contains resiniferatoxin, an extremely potent capsaicin analog tested as an analgesic since 1997. Growth It is a shrub growing to tall, forming multi-stemmed cushion-shaped clumps up to wide. The stems are erect, succulent, superficially like a cactus, four-angled, with short but sharp pairs of spines on the angles, spaced about apart up the stem. Geographical distribution ''Euphorbia resinifera'' is a species of spurge native to Morocco, where it occurs on the slopes of the Atlas Mountains. It is similar to its relative '' Euphorbia echinus'', which occurs on the Moroccan coast and the Canary Islands. Due to its origin it is also called the African spurge. Chemical constituents ''Euphorbia resinifera'' contains a milky fluid or latex, which in its dried form is called ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Euphorbia
''Euphorbia'' is a large and diverse genus of flowering plants, commonly called spurge, in the family (biology), family Euphorbiaceae. Euphorbias range from tiny annual plants to large and long-lived trees, with perhaps the tallest being ''Euphorbia ampliphylla'' at or more. The genus has roughly 2,000 members, making it one of the List of the largest genera of flowering plants, largest genera of flowering plants. It also has one of the largest ranges of ploidy, chromosome counts, along with ''Rumex'' and ''Senecio''. ''Euphorbia antiquorum'' is the type species for the genus ''Euphorbia''. It was first described by Carl Linnaeus in 1753 in ''Species Plantarum''. Some euphorbias are widely available commercially, such as poinsettias at Christmas. Some are commonly cultivated as ornamentals, or collected and highly valued for the aesthetic appearance of their unique floral structures, such as the crown of thorns plant (''Euphorbia milii''). Succulent plant, Succulent euphorbi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Euphorbia Resinifera US Botanic Garden
''Euphorbia'' is a large and diverse genus of flowering plants, commonly called spurge, in the family Euphorbiaceae. Euphorbias range from tiny annual plants to large and long-lived trees, with perhaps the tallest being ''Euphorbia ampliphylla'' at or more. The genus has roughly 2,000 members, making it one of the largest genera of flowering plants. It also has one of the largest ranges of chromosome counts, along with ''Rumex'' and ''Senecio''. ''Euphorbia antiquorum'' is the type species for the genus ''Euphorbia''. It was first described by Carl Linnaeus in 1753 in ''Species Plantarum''. Some euphorbias are widely available commercially, such as poinsettias at Christmas. Some are commonly cultivated as ornamentals, or collected and highly valued for the aesthetic appearance of their unique floral structures, such as the crown of thorns plant (''Euphorbia milii''). Succulent euphorbias from the deserts of Southern Africa and Madagascar have evolved physical characteristi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medicinal Plants Of Africa
Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Succulent Euphorbias
In botany, succulent plants, also known as succulents, are plants with parts that are thickened, fleshy, and engorged, usually to retain water in arid climates or soil conditions. The word ''succulent'' comes from the Latin word ''sucus'', meaning "juice" or "sap". Succulents may store water in various structures, such as leaf, leaves and Plant stem, stems. The water content of some succulent organs can get up to 90–95%, such as ''Glottiphyllum semicyllindricum'' and ''Mesembryanthemum barkleyii''. Some definitions also include roots, thus geophytes that survive unfavorable periods by dying back to underground storage organs (caudex) may be regarded as succulents. The habitats of these water-preserving plants are often in areas with high temperatures and low rainfall, such as deserts, but succulents may be found even in Alpine climate, alpine ecosystems growing in rocky or sandy soil. Succulents are characterized by their ability to thrive on limited water sources, such as mist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endemic Flora Of Morocco
Endemism is the state of a species being found only in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found elsewhere. For example, the Cape sugarbird is found exclusively in southwestern South Africa and is therefore said to be ''endemic'' to that particular part of the world. An endemic species can also be referred to as an ''endemism'' or, in scientific literature, as an ''endemite''. Similarly, many species found in the Western ghats of India are examples of endemism. Endemism is an important concept in conservation biology for measuring biodiversity in a particular place and evaluating the risk of extinction for species. Endemism is also of interest in evolutionary biology, because it provides clues about how changes in the environment cause species to undergo range shifts (potentially expanding their range into a larger area or becoming ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Discovery
In the fields of medicine, biotechnology, and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipitous discovery, as with penicillin. More recently, chemical libraries of synthetic small molecules, natural products, or extracts were screened in intact cells or whole organisms to identify substances that had a desirable therapeutic effect in a process known as classical pharmacology. After sequencing of the human genome allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets which are hypothesized to be disease-modifying in a process known as reverse pharmacology. Hits from these screens are then tested in cells and then in animals for efficacy. Modern drug discovery i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TRPV1
The transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the ''TRPV1'' gene. It was the first isolated member of the transient receptor potential vanilloid receptor proteins that in turn are a sub-family of the transient receptor potential protein group. This protein is a member of the TRPV group of Transient receptor potential channel, transient receptor potential family of ion channels. Fatty acid Fatty acid metabolism, metabolites with affinity for this receptor are produced by cyanobacteria, which Divergent evolution, diverged from eukaryotes at least 2billion years ago. The function of TRPV1 is detection and regulation of body temperature. In addition, TRPV1 provides a sensation of scalding heat and pain (nociception). In primary afferent sensory neurons, it cooperates with TRPA1 (a chemical irritant receptor) to mediate the detection of noxio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vanilloids
The vanilloids are compounds which possess a vanillyl group. They include vanillyl alcohol, vanillin, vanillic acid, acetovanillon, vanillylmandelic acid, homovanillic acid, capsaicin, etc. Isomers are the isovanilloids. : A number of vanilloids, most notably capsaicin, bind to the TRPV1, transient receptor potential vanilloid type 1 (TRPV1) receptor, an ion channel which naturally responds to noxious stimuli such as high temperatures and acidic pH. This action is responsible for the burning sensation experienced after eating capsicum, spicy peppers. Endogenously generated chemicals that trigger the TRPV1 channel of the vanilloids class are referred to as endovanilloids including anandamide, 20-hydroxyeicosatetraenoic acid (20-HETE), N-arachidonoyl dopamine (NADA) and N-oleoyl-dopamine (). Fatty-acid amide hydrolase 1, Fatty acid amide hydrolase (FAAH), is a crucial enzyme for endovanilloid, and the N-Acylethanolamine, ''N''-acylethanolamines (NAEs), catabolism at TRPV1, and oth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Euphorbium
:''Euphorbium can also be a synonym of the genus Euphorbia.'' Euphorbium, an acrid dull-yellow or brown resin, consisting of the concreted milky juice of several species of Euphorbia, cactus-like perennial plants indigenous to Morocco. It dissolves in alcohol, ether and turpentine; in water it is only slightly soluble. It consists of two or more resins and a substance euphorbone, C20H36O or C15H24O. Pliny the Elder states that the name of the drug was given to it in honor of Euphorbus, the physician of Juba II, king of Mauretania. In former times euphorbium was valued in medicine for its drastic, purgative and emetic properties. According to Robert Bentley's (botanist) book of Organic Medical Materials from 1887 The latex of '' Euphorbia resinifera'' contains Resiniferatoxin, an ultra potent capsaicin Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) (, rarely ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a potent Irr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canary Island
The Canary Islands (; ) or Canaries are an archipelago in the Atlantic Ocean and the southernmost Autonomous Community of Spain. They are located in the northwest of Africa, with the closest point to the continent being 100 kilometres (62 miles) away. The islands have a population of 2.25 million people and are the most populous overseas special territory of the European Union. The seven main islands are from largest to smallest in area, Tenerife, Fuerteventura, Gran Canaria, Lanzarote, La Palma, La Gomera, and El Hierro. The only other populated island is La Graciosa, which administratively is dependent on Lanzarote. The archipelago includes many smaller islands and islets, including Alegranza, Isla de Lobos, Montaña Clara, Roque del Oeste, and Roque del Este. It includes a number of rocks, including Garachico and Anaga. The island chain used to be referred to as "the Fortunate Isles". The Canary Islands are the southernmost region of Spain, and the largest and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morocco
Morocco, officially the Kingdom of Morocco, is a country in the Maghreb region of North Africa. It has coastlines on the Mediterranean Sea to the north and the Atlantic Ocean to the west, and has land borders with Algeria to Algeria–Morocco border, the east, and the disputed territory of Western Sahara to Morocco–Western Sahara border, the south. Morocco also claims the Spain, Spanish Enclave and exclave, exclaves of Ceuta, Melilla and Peñón de Vélez de la Gomera, and several small Plazas de soberanía, Spanish-controlled islands off its coast. It has a population of approximately 37 million. Islam is both the official and predominant religion, while Arabic and Berber are the official languages. Additionally, French and the Moroccan dialect of Arabic are widely spoken. The culture of Morocco is a mix of Arab culture, Arab, Berbers, Berber, Culture of Africa, African and Culture of Europe, European cultures. Its capital is Rabat, while its largest city is Casablanca. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Euphorbia Echinus
''Euphorbia'' is a large and diverse genus of flowering plants, commonly called spurge, in the family Euphorbiaceae. Euphorbias range from tiny annual plants to large and long-lived trees, with perhaps the tallest being ''Euphorbia ampliphylla'' at or more. The genus has roughly 2,000 members, making it one of the largest genera of flowering plants. It also has one of the largest ranges of chromosome counts, along with ''Rumex'' and ''Senecio''. ''Euphorbia antiquorum'' is the type species for the genus ''Euphorbia''. It was first described by Carl Linnaeus in 1753 in ''Species Plantarum''. Some euphorbias are widely available commercially, such as poinsettias at Christmas. Some are commonly cultivated as ornamentals, or collected and highly valued for the aesthetic appearance of their unique floral structures, such as the crown of thorns plant (''Euphorbia milii''). Succulent euphorbias from the deserts of Southern Africa and Madagascar have evolved physical characteristi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
