Esophageal Varices
Esophageal varices are extremely Vasodilation, dilated sub-mucosal veins in the lower third of the esophagus. They are most often a consequence of portal hypertension, commonly due to cirrhosis. People with esophageal varices have a strong tendency to develop severe bleeding which left untreated can be exsanguination, fatal. Esophageal varices are typically diagnosed through an esophagogastroduodenoscopy. Pathogenesis The upper two thirds of the esophagus are drained via the esophageal veins, which carry deoxygenated blood from the esophagus to the azygos vein, which in turn drains directly into the superior vena cava. These veins have no part in the development of esophageal varices. The lower one third of the esophagus is drained into the superficial veins lining the esophageal mucosa, which drain into the left gastric vein, which in turn drains directly into the portal vein. These superficial veins (normally only approximately 1 mm in diameter) become distended up to 1� ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Wale Mark
A wale mark, red wale sign or wale sign is an endoscopic sign suggestive of recent hemorrhage, or propensity to bleed, seen in individuals with esophageal varices at the time of endoscopy. The mark has the appearance of a longitudinal red streak located on an esophageal varix. It derives its name from the visual similarity to patterns seen in the textile corduroy. Similar lesions that are suggestive of recent or impending bleeding from esophageal varices include the ''cherry-red'' spot, which is circular and red in colour. Bleeding risk of esophageal varices can be ascertained at the time of endoscopy by evaluating for the presence of these markers.{{cite journal , vauthors=Beppu K, Inokuchi K, Koyanagi N, etal , title=Prediction of variceal hemorrhage by esophageal endoscopy , journal=Gastrointest. Endosc. , volume=27 , issue=4 , pages=213–8 , date=November 1981 , pmid=6975734 See also * Esophageal varices Esophageal varices are extremely Vasodilation, dilated sub-mucosal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Exsanguination
Exsanguination is the loss of blood from the circulatory system of a vertebrate, usually leading to death. The word comes from the Latin 'sanguis', meaning blood, and the prefix 'ex-', meaning 'out of'. Exsanguination has long been used as a method of animal slaughter. Humane slaughter must ensure the animal is rendered insensible to pain, whether through a captive bolt or other process, prior to the bloodletting. Depending upon the health of the individual, a person usually dies from losing half to two-thirds of their blood; a loss of roughly one-third of the blood volume is Critical condition, considered very serious. Even a single deep cut can warrant Surgical suture, suturing and Inpatient care, hospitalization, especially if Trauma (medicine), trauma, a vein or artery, or another comorbidity is involved. In the past, bloodletting was a common medical procedure or therapy, now rarely used in medicine. Slaughtering of animals Exsanguination is used as a Animal slaughter, s ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gastric Varices
Gastric varices are dilated submucosal veins in the lining of the stomach, which can be a life-threatening cause of bleeding in the upper gastrointestinal tract. They are most commonly found in patients with portal hypertension, or elevated pressure in the portal vein system, which may be a complication of cirrhosis. Gastric varices may also be found in patients with thrombosis of the splenic vein, into which the short gastric veins that drain the fundus of the stomach flow. The latter may be a complication of acute pancreatitis, pancreatic cancer, or other abdominal tumours, as well as hepatitis C. Gastric varices and associated bleeding are a potential complication of schistosomiasis resulting from portal hypertension. Patients with bleeding gastric varices can present with bloody vomiting ( hematemesis), dark, tarry stools ( melena), or rectal bleeding. The bleeding may be brisk, and patients may soon develop shock. Treatment of gastric varices can include injection of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Splenectomy
A splenectomy is the surgical procedure that partially or completely removes the spleen. The spleen is an important organ in regard to immunological function due to its ability to efficiently destroy encapsulated bacteria. Therefore, removal of the spleen runs the risk of overwhelming post-splenectomy infection, a medical emergency and rapidly fatal disease caused by the inability of the body's immune system to properly fight infection following splenectomy or asplenia. Common indications for splenectomy include trauma, tumors, splenomegaly or for hematological disease such as sickle cell anemia or thalassemia. Indications The spleen is an organ located in the abdomen next to the stomach. It is composed of red pulp which filters the blood, removing foreign material, damaged and worn out red blood cells. It also functions as a storage site for iron, red blood cells and platelets. The rest (~25%) of the spleen is known as the white pulp and functions like a large lymph n ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Anastomosis
An anastomosis (, : anastomoses) is a connection or opening between two things (especially cavities or passages) that are normally diverging or branching, such as between blood vessels, leaf veins, or streams. Such a connection may be normal (such as the foramen ovale in a fetus' heart) or abnormal (such as the patent foramen ovale in an adult's heart); it may be acquired (such as an arteriovenous fistula) or innate (such as the arteriovenous shunt of a metarteriole); and it may be natural (such as the aforementioned examples) or artificial (such as a surgical anastomosis). The reestablishment of an anastomosis that had become blocked is called a reanastomosis. Anastomoses that are abnormal, whether congenital or acquired, are often called fistulas. The term is used in medicine, biology, mycology, geology, and geography. Etymology Anastomosis: medical or Modern Latin, from Greek ἀναστόμωσις, anastomosis, "outlet, opening", Greek ana- "up, on, upon", stoma "mouth" ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Varicose Veins
Varicose veins, also known as varicoses, are a medical condition in which superficial veins become enlarged and twisted. Although usually just a cosmetic ailment, in some cases they cause fatigue, pain, itch, itching, and cramp, nighttime leg cramps. These veins typically develop in the legs, just under the skin. Their complications can include bleeding, ulcer (dermatology), skin ulcers, and superficial thrombophlebitis. Varices in the scrotum are known as varicocele, while those around the Human anus, anus are known as hemorrhoids. The physical, social, and psychological effects of varicose veins can lower their bearers' quality of life. Varicose veins have no specific cause. Risk factors include obesity, lack of exercise, leg trauma, and family history of the condition. They also develop more commonly during pregnancy. Occasionally they result from chronic venous insufficiency. Underlying causes include weak or damaged valves in the veins. They are typically diagnosed by examina ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rectum
The rectum (: rectums or recta) is the final straight portion of the large intestine in humans and some other mammals, and the gut in others. Before expulsion through the anus or cloaca, the rectum stores the feces temporarily. The adult human rectum is about long, and begins at the rectosigmoid junction (the end of the sigmoid colon) at the level of the third sacral vertebra or the sacral promontory depending upon what definition is used. Its diameter is similar to that of the sigmoid colon at its commencement, but it is dilated near its termination, forming the rectal ampulla. It terminates at the level of the anorectal ring (the level of the puborectalis sling) or the dentate line, again depending upon which definition is used. In humans, the rectum is followed by the anal canal, which is about long, before the gastrointestinal tract terminates at the anal verge. The word rectum comes from the Latin '' rēctum intestīnum'', meaning ''straight intestine''. Struc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Stomach
The stomach is a muscular, hollow organ in the upper gastrointestinal tract of Human, humans and many other animals, including several invertebrates. The Ancient Greek name for the stomach is ''gaster'' which is used as ''gastric'' in medical terms related to the stomach. The stomach has a dilated structure and functions as a vital organ in the digestive system. The stomach is involved in the gastric phase, gastric phase of digestion, following the cephalic phase in which the sight and smell of food and the act of chewing are stimuli. In the stomach a chemical breakdown of food takes place by means of secreted digestive enzymes and gastric acid. It also plays a role in regulating gut microbiota, influencing digestion and overall health. The stomach is located between the esophagus and the small intestine. The pyloric sphincter controls the passage of partially digested food (chyme) from the stomach into the duodenum, the first and shortest part of the small intestine, where p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Collateral Circulation
Collateral circulation is the alternate Circulatory system, circulation around a blocked blood vessel, artery or vein via another path, such as nearby minor vessels. It may occur via preexisting vascular redundancy (analogous to redundancy (engineering), engineered redundancy), as in the circle of Willis in the brain, or it may occur via new branches formed between adjacent blood vessels (neovascularization), as in the eye after a retinal embolism or in the brain when an instance of arterial constriction occurs due to Moyamoya disease. Its formation may be related by pathological conditions such as high vascular resistance or ischaemia. It is occasionally also known as accessory circulation, auxiliary circulation, or secondary circulation. It has surgery, surgically created analogues in which shunt (medical), shunts or circulatory anastomosis, anastomoses are constructed to bypass circulatory problems. An example of the usefulness of collateral circulation is a systemic thromboem ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Left Gastric Vein
The left gastric vein (or coronary vein) is a vein that derives from tributaries draining the lesser curvature of the stomach. Structure The left gastric vein runs from right to left along the lesser curvature of the stomach. It passes to the esophageal opening of the stomach, where it receives some esophageal veins. It then turns backward and passes from left to right behind the omental bursa. It drains into the portal vein near the superior border of the pancreas. Function The left gastric vein drains deoxygenated blood from the lesser curvature of the stomach. It also acts as collaterals between the portal vein The portal vein or hepatic portal vein (HPV) is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver. This blood contains nutrients and toxins extracted from digested contents. Approxima ... and the systemic venous system of the lower esophagus ( azygos vein). Clinical significance The esophageal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Superior Vena Cava
The superior vena cava (SVC) is the superior of the two venae cavae, the great venous trunks that return deoxygenated blood from the systemic circulation to the right atrium of the heart. It is a large-diameter (24 mm) short length vein that receives venous return from the upper half of the body, above the diaphragm. Venous return from the lower half, below the diaphragm, flows through the inferior vena cava. The SVC is located in the anterior right superior mediastinum. It is the typical site of central venous access via a central venous catheter or a peripherally inserted central catheter. Mentions of "the cava" without further specification usually refer to the SVC. Structure The superior vena cava is formed by the left and right brachiocephalic veins, which receive blood from the upper limbs, head and neck, behind the lower border of the first right costal cartilage. It passes vertically downwards behind the first intercostal space and receives the azygos vei ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Azygos Vein
The azygos vein (from Ancient Greek ἄζυγος (ázugos), meaning 'unwedded' or 'unpaired') is a vein running up the right side of the thoracic vertebral column draining itself towards the superior vena cava. It connects the systems of superior vena cava and inferior vena cava and can provide an alternative path for blood to the right atrium when either of the venae cavae is blocked. Structure The azygos vein transports deoxygenated blood from the posterior walls of the thorax and abdomen into the superior vena cava. It is formed by the union of the ascending lumbar veins with the right subcostal veins at the level of the 12th thoracic vertebra, ascending to the right of the descending aorta and thoracic duct, passing behind the right crus of diaphragm, anterior to the vertebral bodies of T12 to T5 and right posterior intercostal arteries. At the level of T4 vertebrae, it arches over the root of the right lung from behind to the front to join the superior vena cava. The tra ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |