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Echinobase
Echinobase is a Model Organism Database (MOD). It supports the international research community by providing a centralized, integrated web based resource to access the diverse and rich, functional genomics data of echinoderm evolution, development and gene regulatory networks. BI Arshinoff, GA Cary, K Karimi, S Foley, S Agalakov, F Delgado, VS Lotay, CJ Ku, TJ Pells, TR Beatman, E Kim, RA Cameron, PD Vize, CA Telmer, JC Croce, CA Ettensohn, VF HinmanEchinobase: leveraging an extant model organism database to build a knowledgebase supporting research on the genomics and biology of echinoderms Nucleic Acids Research, 2021, doi:10.1093/nar/gkab1005 Genomic research data and tools are available for searching, browsing and bioinformatic analysis of genomes, genes, and transcripts. Echinobase provides a critical data sharing infrastructure for other NIH-funded projects and enhances the availability and visibility of echinoderm data to the broader biomedical research community. Su ...
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Model Organism Databases
Model organism databases (MODs) are biological databases Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genom ..., or knowledgebases, dedicated to the provision of in-depth biological data for intensively studied model organisms. MODs allow researchers to easily find background information on large sets of genes, plan experiments efficiently, combine their data with existing knowledge, and construct novel hypotheses. They allow users to analyse results and interpret datasets, and the data they generate are increasingly used to describe less well studied species. Where possible, MODs share common approaches to collect and represent biological information. For example, all MODs use the Gene Ontology (GO) to describe functions, processes and cellular locations of specific gene products. Pr ...
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Xenbase
Xenbase is a Model Organism Database (MOD), providing informatics resources, as well as genomic and biological data on Xenopus frogs.K. Karimi et al. (2017Xenbase: a genomic, epigenomic and transcriptomic model organism database Nucleic Acids Research (NAR), gkx936 Xenbase has been available since 1999, and covers both X. laevis and X. tropicalis Xenopus varieties. As of 2013 all of its services are running on virtual machines in a private cloud environment, making it one of the first MODs to do so.K. Karimi and P.D. Vize (2014)The Virtual Xenbase: transitioning an online bioinformatics resource to a private cloud Database, doi: 10.1093/database/bau108 Other than hosting genomics data and tools, Xenbase supports the Xenopus research community though profiles for researchers and laboratories, and job and events postings. Xenbase's Software and Hardware Platform Xenbase runs in a cloud environment. Its virtual machines are running in a VMware vSphere environment on two servers, wi ...
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Acanthaster Planci
The crown-of-thorns starfish (frequently abbreviated to COTS), ''Acanthaster planci'', is a large starfish that preys upon hard, or stony, coral polyps (Scleractinia). The crown-of-thorns starfish receives its name from venomous thorn-like spines that cover its upper surface, resembling the biblical crown of thorns. It is one of the largest starfish in the world. ''A. planci'' has a very wide Indo-Pacific distribution. It is perhaps most common around Australia, but can occur at tropical and subtropical latitudes from the Red Sea and the East African coast across the Indian Ocean, and across the Pacific Ocean to the west coast of Central America. It occurs where coral reefs or hard coral communities occur in the region. Description The body form of the crown-of-thorns starfish is fundamentally the same as that of a typical starfish, with a central disk and radiating arms. Its special traits, however, include being disc-shaped, multiple-armed, flexible, prehensile, and heavily ...
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Strongylocentrotus Purpuratus
''Strongylocentrotus purpuratus'', the purple sea urchin, lives along the eastern edge of the Pacific Ocean extending from Ensenada, Mexico, to British Columbia, Canada. This sea urchin species is deep purple in color, and lives in lower inter-tidal and nearshore sub-tidal communities. Its eggs are orange when secreted in water. January, February, and March function as the typical active reproductive months for the species. Sexual maturity is reached around two years. It normally grows to a diameter of about 10 cm (4 inches) and may live as long as 70 years. Role in biomedical research The initial discovery of three distinct eukaryotic DNA-dependent RNA polymerases was made using ''S. purpuratus'' as a model organism. While embryonic development is still a major part of the utilization of the sea urchin, studies on urchin's position as an evolutionary marvel have become increasingly frequent. Orthologs to human diseases have led scientists to investigate poten ...
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JavaScript
JavaScript (), often abbreviated as JS, is a programming language that is one of the core technologies of the World Wide Web, alongside HTML and CSS. As of 2022, 98% of Website, websites use JavaScript on the Client (computing), client side for Web page, webpage behavior, often incorporating third-party Library (computing), libraries. All major Web browser, web browsers have a dedicated JavaScript engine to execute the Source code, code on User (computing), users' devices. JavaScript is a High-level programming language, high-level, often Just-in-time compilation, just-in-time compiled language that conforms to the ECMAScript standard. It has dynamic typing, Prototype-based programming, prototype-based object-oriented programming, object-orientation, and first-class functions. It is Programming paradigm, multi-paradigm, supporting Event-driven programming, event-driven, functional programming, functional, and imperative programming, imperative programming paradigm, programmin ...
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AJAX
Ajax may refer to: Greek mythology and tragedy * Ajax the Great, a Greek mythological hero, son of King Telamon and Periboea * Ajax the Lesser, a Greek mythological hero, son of Oileus, the king of Locris * ''Ajax'' (play), by the ancient Greek tragedian Sophocles, about Ajax the Great Arts and entertainment Fictional characters * Ajax Duckman, in the animated television series ''Duckman'' * Marvel Comics: ** Ajax the Greater, another name for Ajak, one of the Eternals from Marvel Comics ** Ajax the Lesser, another name for Arex, one of the Eternals from Marvel Comics ** Ajax, a member of the Pantheon appearing in Marvel Comics ** Ajax (Francis Fanny), a fictional supervillain first appearing in ''Deadpool'' #14 * Martian Manhunter, a DC Comics superhero called Ajax in Brazil and Portugal * Ajax, a '' Call of Duty: Black Ops 4'' operative * Ajax, from the video game '' Genshin Impact'' Music * A-Jax (band), a South Korean boy band * Ajax (band), an electronic music band ...
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WebSphere Application Server
WebSphere Application Server (WAS) is a software product that performs the role of a web application server. More specifically, it is a software framework and middleware that hosts Java-based web applications. It is the flagship product within IBM's WebSphere software suite. It was initially created by Donald F. Ferguson, who later became CTO of Software for Dell. The first version was launched in 1998. This project was an offshoot from IBM HTTP Server team starting with the Domino Go web server. Architecture WebSphere Application Server (WAS) is built using open standards such as Java EE, XML, and Web Services. It runs on the following platforms: Windows, AIX, Linux, Solaris, IBM i and z/OS. Beginning with Version 6.1 and now into Version 9.0, the open standard specifications are aligned and common across all the platforms. Platform exploitation, to the extent it takes place, is done ''below'' the open standard specification line. It works with a number of Web servers incl ...
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IBM Db2
Db2 is a family of data management products, including database servers, developed by IBM. It initially supported the relational model, but was extended to support object–relational features and non-relational structures like JSON and XML. The brand name was originally styled as DB/2, then DB2 until 2017 and finally changed to its present form. History Unlike other database vendors, IBM previously produced a platform-specific Db2 product for each of its major operating systems. However, in the 1990s IBM changed track and produced a Db2 common product, designed with a mostly common code base for L-U-W (Linux-Unix-Windows); DB2 for System z and DB2 for IBM i are different. As a result, they use different drivers. DB2 traces its roots back to the beginning of the 1970s when Edgar F. Codd, a researcher working for IBM, described the theory of relational databases, and in June 1970 published the model for data manipulation. In 1974, the IBM San Jose Research center dev ...
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OMIM
Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship. , approximately 9,000 of the over 25,000 entries in OMIM represented phenotypes; the rest represented genes, many of which were related to known phenotypes. Versions and history OMIM is the online continuation of Dr. Victor A. McKusick's ''Mendelian Inheritance in Man'' (MIM), which was published in 12 editions between 1966 and 1998.McKusick, V. A. ''Mendelian Inheritance in Man. Catalogs of Autosomal Dominant, Autosomal Recessive and X-Linked Phenotypes.'' Baltimore, MD: Johns Hopkins University Press, 1st ed, 1996; 2nd ed, 1969; 3rd ed, 1971; 4th ed, 1975; 5th ed, 1978; 6th ed, 1983; 7th ed, 1986; 8th ed, 1988; 9th ed, 1990; 10th ed, 1992. Nearly all of the 1,486 entries in the first edition of MIM discussed phenotypes. MIM/OMIM is produced and curated at the Johns Hopkins School of Medic ...
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Disease Ontology
The Disease Ontology (DO) is a formal ontology of human disease. ThDisease Ontology projectis hosted at thInstitute for Genome Sciencesat the University of Maryland School of Medicine. The Disease Ontology project was initially developed in 2003 at Northwestern University to address the need for a purpose-built ontology that covers the full spectrum of disease concepts annotated within biomedical repositories within an ontological framework that is extensible to meet community needs. The Disease Ontology is an OBO ( Open Biomedical Ontologies) Foundry ontology. Disease Ontology Identifiers (DOIDs) consist of the prefix DOID: followed by number, for example, Alzheimer's disease has the stable identifieDOID:10652 DO is cross-referenced in several resources such as UniProt. Example term The Disease Ontology entry for motor neuron disease in OBO format is given below, showing the links to other classification schemes, including ICD-9, ICD-10, MeSH, SNOMED and UMLS. :id: DOID:231 ...
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Java (programming Language)
Java is a high-level, class-based, object-oriented programming language that is designed to have as few implementation dependencies as possible. It is a general-purpose programming language intended to let programmers ''write once, run anywhere'' ( WORA), meaning that compiled Java code can run on all platforms that support Java without the need to recompile. Java applications are typically compiled to bytecode that can run on any Java virtual machine (JVM) regardless of the underlying computer architecture. The syntax of Java is similar to C and C++, but has fewer low-level facilities than either of them. The Java runtime provides dynamic capabilities (such as reflection and runtime code modification) that are typically not available in traditional compiled languages. , Java was one of the most popular programming languages in use according to GitHub, particularly for client–server web applications, with a reported 9 million developers. Java was originally de ...
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