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Dawson Fingers
Multiple sclerosis and other demyelinating diseases of the central nervous system (CNS) produce lesions (demyelinated areas in the CNS) and glial scars or scleroses. They present different shapes and histological findings according to the underlying condition that produces them. Demyelinating diseases are traditionally classified in two kinds: demyelinating myelinoclastic diseases and demyelinating leukodystrophic diseases. In the first group a normal and healthy myelin is destroyed by a toxic, chemical or autoimmune substance. In the second group, myelin is abnormal and degenerates. The second group was denominated dysmyelinating diseases by Poser Therefore, since Poser demyelinating diseases normally refers to the myelinoclastic part. Demyelinating diseases of the CNS can be classified according to their pathogenesis into five non-exclusing categories: demyelination due to inflammatory processes, viral demyelination, demyelination caused by acquired metabolic derangements, hypo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diffuse Myelinoclastic Sclerosis
Diffuse myelinoclastic sclerosis, sometimes referred to as Schilder's disease, is a very infrequent neurodegenerative disease that presents clinically as pseudotumoural demyelinating lesions, making its diagnosis difficult. It usually begins in childhood, affecting children between 5 and 14 years old, but cases in adults are also possible. This disease is considered one of the borderline forms of multiple sclerosis because some authors consider them different diseases and others MS variants. Other diseases in this group are neuromyelitis optica (NMO), Balo concentric sclerosis and Marburg multiple sclerosis. Symptoms and signs Symptoms are similar to those in multiple sclerosis and may include dementia, aphasia, seizures, personality changes, poor attention, tremors, balance instability, incontinence, muscle weakness, headache, vomiting, and vision and speech impairment. Other symptoms include weakness on one side of the body, muscle stiffness, hearing problems, and loss of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Lumsden
Charles J. Lumsden (born 1949) is a Canadian biologist in the Department of Medicine and Institute of Medical Science, University of Toronto. He has been an early proponent of sociobiology, looking to our genetic nature to supplement culture in describing what makes us human. He wrote two influential books in collaboration with Edward O. Wilson ''Genes, Mind and Culture: The Coevolutionary Process.'' (Harvard University Press, 1981) and ''Promethean Fire: Reflections on the Origin of Mind'' (Harvard University Press, 1983). Part of his interests lies in the mathematical and philosophical bases of physical theory in biology, and the origins of creativity Creativity is the ability to form novel and valuable Idea, ideas or works using one's imagination. Products of creativity may be intangible (e.g. an idea, scientific theory, Literature, literary work, musical composition, or joke), or a physica .... He has also co-edited biology textbooks, notably ''Physical Theory in Biology: ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal cord is hollow and contains a structure called the central canal, which contains cerebrospinal fluid. The spinal cord is also covered by meninges and enclosed by the neural arches. Together, the brain and spinal cord make up the central nervous system. In humans, the spinal cord is a continuation of the brainstem and anatomically begins at the occipital bone, passing out of the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it tapers to become the cauda equina. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thalamus
The thalamus (: thalami; from Greek language, Greek Wikt:θάλαμος, θάλαμος, "chamber") is a large mass of gray matter on the lateral wall of the third ventricle forming the wikt:dorsal, dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, known as the thalamocortical radiations, allowing hub (network science), hub-like exchanges of information. It has several functions, such as the relaying of sensory neuron, sensory and motor neuron, motor signals to the cerebral cortex and the regulation of consciousness, sleep, and alertness. Anatomically, the thalami are paramedian symmetrical structures (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain. It forms during embryonic development as the main product of the diencephalon, as first recognized by the Swiss embryologist and anatomist Wilhelm His Sr. in 1893. Anatomy The thalami ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerebellum
The cerebellum (: cerebella or cerebellums; Latin for 'little brain') is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as it or even larger. In humans, the cerebellum plays an important role in motor control and cognition, cognitive functions such as attention and language as well as emotion, emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to motor coordination, coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine motor skill, fine movement, sense of balance, equilibrium, list of human positions, posture, and motor learning in humans. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cingulate Gyrus
The cingulate cortex is a part of the brain situated in the medial aspect of the cerebral cortex. The cingulate cortex includes the entire cingulate gyrus, which lies immediately above the corpus callosum, and the continuation of this in the cingulate sulcus. The cingulate cortex is usually considered part of the limbic lobe. It receives inputs from the thalamus and the neocortex, and projects to the entorhinal cortex via the cingulum (anatomy), cingulum. It is an integral part of the limbic system, which is involved with emotion formation and processing, learning, and memory. The combination of these three functions makes the cingulate gyrus highly influential in linking motivational outcomes to behavior (e.g. a certain action induced a positive emotional response, which results in learning). This role makes the cingulate cortex highly important in disorders such as Major depressive disorder, depression and schizophrenia. It also plays a role in executive function and respirator ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Motor Cortex
The motor cortex is the region of the cerebral cortex involved in the planning, motor control, control, and execution of voluntary movements. The motor cortex is an area of the frontal lobe located in the posterior precentral gyrus immediately anterior to the central sulcus. Components The motor cortex can be divided into three areas: 1. The primary motor cortex is the main contributor to generating neural impulses that pass down to the spinal cord and control the execution of movement. However, some of the other motor areas in the brain also play a role in this function. It is located on the anterior paracentral lobule on the medial surface. 2. The premotor cortex is responsible for some aspects of motor control, possibly including the preparation for movement, the sensory guidance of movement, the spatial guidance of reaching, or the direct control of some movements with an emphasis on control of proximal and trunk muscles of the body. Located anterior to the primary mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MS Demyelinisation KB 10x
MS, ms, Ms, M.S., etc. may refer to: Arts and entertainment * ''Ms.'' (magazine), an American feminist magazine * Metal Storm (webzine), a heavy metal website based in Estonia Businesses and organizations * MS-13, criminal gang * Młodzi Socjaliści (Young Socialists), a former Polish socialist youth organization * Morgan Stanley, a US investment bank (NYSE stock symbol: MS) * Mjólkursamsalan, an Icelandic dairy company * Microsoft, an American multinational corporation and technology company * Motorola Solutions, an American communications equipment manufacturer Educational qualifications * Master of Science, a master's degree in the field of science * Master of Surgery, an advanced medical degree * Master Sommelier, a terminal degree in the field of wine * '' Mastère spécialisé'', a French postgraduate ''grande école'' master's degree Medicine * Mitral stenosis, narrowing of the mitral valve of the heart * Morphine sulfate, an opiate pain-relieving drug * Multiple scler ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovoid
An oval () is a closed curve in a plane which resembles the outline of an egg. The term is not very specific, but in some areas of mathematics (projective geometry, technical drawing, etc.), it is given a more precise definition, which may include either one or two axes of symmetry of an ellipse. In common English, the term is used in a broader sense: any shape which reminds one of an egg. The three-dimensional version of an oval is called an ovoid. Oval in geometry The term oval when used to describe curves in geometry is not well-defined, except in the context of projective geometry. Many distinct curves are commonly called ovals or are said to have an "oval shape". Generally, to be called an oval, a plane curve should ''resemble'' the outline of an egg or an ellipse. In particular, these are common traits of ovals: * they are differentiable (smooth-looking), simple (not self-intersecting), convex, closed, plane curves; * their shape does not depart much from that of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glial Cell Types
Glia, also called glial cells (gliocytes) or neuroglia, are non-neuronal cells in the central nervous system (the brain and the spinal cord) and in the peripheral nervous system that do not produce electrical impulses. The neuroglia make up more than one half the volume of neural tissue in the human body. They maintain homeostasis, form myelin, and provide support and protection for neurons. In the central nervous system, glial cells include oligodendrocytes (that produce myelin), astrocytes, ependymal cells and microglia, and in the peripheral nervous system they include Schwann cells (that produce myelin), and satellite cells. Function They have four main functions: * to surround neurons and hold them in place * to supply nutrients and oxygen to neurons * to insulate one neuron from another * to destroy pathogens and remove dead neurons. They also play a role in neurotransmission and synaptic connections, and in physiological processes such as breathing. While glia were t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Complement System
The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. Despite being part of the innate immune system, the complement system can be recruited and brought into action by antibodies generated by the adaptive immune system. The complement system consists of a number of small, inactive, liver synthesized protein precursors circulating in the blood. When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end result of this ''complement activation'' or ''complement fixation'' cascade is stimulation of phagocytes to clear foreign and damaged material, inflammation to attract additional phagocytes, and activation of the cell-killi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
