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Toxicology Tests
Toxicology is a scientific discipline Discipline is the self-control that is gained by requiring that rules or orders be obeyed, and the ability to keep working at something that is difficult. Disciplinarians believe that such self-control is of the utmost importance and enforce a ..., overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosis, diagnosing and therapy, treating exposures to toxins and toxicants. The dose–response relationship, relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or Chronic toxicity, chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxicology Research At FDA (NCTR 1193) (6009043040)
Toxicology is a scientific discipline (academia), discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosis, diagnosing and therapy, treating exposures to toxins and toxicants. The dose–response relationship, relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or Chronic toxicity, chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivatin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poisoning
Poisoning is the harmful effect which occurs when Toxicity, toxic substances are introduced into the body. The term "poisoning" is a derivative of poison, a term describing any chemical substance that may harm or kill a living organism upon ingestion. Poisoning can be brought on by swallowing, inhaling, injecting or absorbing toxins through the skin. Toxicology is the practice and study of symptoms, mechanisms, diagnoses, and treatments correlated to poisoning. Levels of Exposure When a living organism is introduced to a poison, the Signs and symptoms, symptoms that follow successful contact develop in Dose–response relationship, close relation to the degree of exposure. Acute exposure Acute toxicity, Acute toxicity/poisoning consists of a living organism being harmfully exposed to poison once or more times during a brief period, with symptoms manifesting within 14 days since administration. Chronic exposure Chronic toxicity, Chronic toxicity/poisoning involves a li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
λόγος
''Logos'' (, ; ) is a term used in Western philosophy, psychology and rhetoric, as well as religion (notably Christianity); among its connotations is that of a rational form of discourse that relies on inductive and deductive reasoning. Aristotle first systematized the usage of the word, making it one of the three principles of rhetoric alongside ethos and pathos. This original use identifies the word closely to the structure and content of language or text. Both Plato and Aristotle used the term ''logos'' (along with '' rhema'') to refer to sentences and propositions. Background is related to which is cognate with . The word derives from a Proto-Indo-European root, *leǵ-, which can have the meanings "I put in order, arrange, gather, choose, count, reckon, discern, say, speak". In modern usage, it typically connotes the verbs "account", "measure", "reason" or "discourse".Henry George Liddell and Robert Scott''An Intermediate Greek–English Lexicon'' logos, 1889.Entrat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient Greek
Ancient Greek (, ; ) includes the forms of the Greek language used in ancient Greece and the classical antiquity, ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Greek Dark Ages, Dark Ages (), the Archaic Greece, Archaic or Homeric Greek, Homeric period (), and the Classical Greece, Classical period (). Ancient Greek was the language of Homer and of fifth-century Athens, fifth-century Athenian historians, playwrights, and Ancient Greek philosophy, philosophers. It has contributed many words to English vocabulary and has been a standard subject of study in educational institutions of the Western world since the Renaissance. This article primarily contains information about the Homeric Greek, Epic and Classical periods of the language, which are the best-attested periods and considered most typical of Ancient Greek. From the Hellenistic period (), Ancient Greek was followed by Koine Greek, which is regar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
-logy
''-logy'' is a suffix in the English language, used with words originally adapted from Ancient Greek ending in ('). The earliest English examples were anglicizations of the French '' -logie'', which was in turn inherited from the Latin '' -logia''. The suffix became productive in English from the 18th century, allowing the formation of new terms with no Latin or Greek precedent. The English suffix has two separate main senses, reflecting two sources of the suffix in Greek: *a combining form used in the names of school or bodies of knowledge, e.g., ''theology'' (loaned from Latin in the 14th century) or ''sociology''. In words of the type ''theology'', the suffix is derived originally from (''-log-'') (a variant of , ''-leg-''), from the Greek verb (''legein'', 'to speak')."-logy." ''The Concise Oxford Dictionary of English Etymology''. Oxford University Press, 1986. retrieved 20 August 2008. The suffix has the sense of "the character or deportment of one who speaks or tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neo-Latin
Neo-LatinSidwell, Keith ''Classical Latin-Medieval Latin-Neo Latin'' in ; others, throughout. (also known as New Latin and Modern Latin) is the style of written Latin used in original literary, scholarly, and scientific works, first in Italy during the Italian Renaissance of the fourteenth and fifteenth centuries, and then across northern Europe after about 1500, as a key feature of the humanist movement. Through comparison with Classical Latin, Latin of the Classical period, scholars from Petrarch onwards promoted a standard of Latin closer to that of the ancient Romans, especially in grammar, style, and spelling. The term ''Neo-Latin'' was however coined much later, probably in Germany in the late eighteenth century, as ''Neulatein'', spreading to French and other languages in the nineteenth century. Medieval Latin had diverged quite substantially from the classical standard and saw notable regional variation and influence from vernacular languages. Neo-Latin attempts to retur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Classical Compound
Neoclassical compounds are compound words composed from combining forms (which act as affixes or stems) derived from Classical_language#Classical_studies, classical languages (classical Latin or ancient Greek) root (linguistics), roots. Neo-Latin comprises many such words and is a substantial component of the technology, technical and science, scientific lexicon of English language, English and other languages, via international scientific vocabulary (ISV). For example, Greek ''wikt:bio-#Prefix, bio-'' combines with ''wikt:-graphy#Suffix, -graphy'' to form ''biography'' ("life" + "writing/recording"). Source of international technical vocabulary Neoclassical compounds represent a significant source of Neo-Latin vocabulary. Moreover, since these words are composed from classical languages whose prestige is or was respected throughout the Western European culture, these words typically appear in many different languages. Their widespread use makes technical writing generally acces ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leukemia
Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia—acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myelo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosome-inactivating Protein
A ribosome-inactivating protein (RIP) is a protein synthesis inhibitor that acts at the eukaryote, eukaryotic ribosome. This protein family describes a large family of such proteins that work by acting as rRNA N-glycosylase (EC 3.2.2.22). They inactivate 60S ribosomal subunits by an N-glycosidic cleavage, which releases a specific adenine base from the sugar-phosphate backbone of 28S rRNA. RIPs exist in bacteria and plants. Members of the family include shiga toxins, and type I (e.g. trichosanthin and luffin) and type II (e.g. ricin, agglutinin, and abrin) ribosome inactivating proteins (RIPs). All these toxins are structurally related. RIPs have been of considerable interest because of their potential use, conjugated with Monoclonal antibody, monoclonal antibodies, as immunotoxins to treat cancers. Further, trichosanthin has been shown to have potent activity against HIV-1-infected T cells and macrophages. Elucidation of the structure-function relationships of RIPs has therefore b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
