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Oxytocin Receptor Agonists
An oxytocin receptor agonist is a chemical compound, compound that acts as an agonist of the oxytocin receptor. Oxytocin receptor agonists are used medically to labor induction, induce labor, galactogogue, promote lactation, and for other uses. In addition, oxytocin receptor agonists are of theoretical interest for the potential treatment of social disorders, such as autism and social anxiety. Small-molecule oxytocin receptor agonists are considered to be more promising for such uses due to better pharmacokinetic profiles, such as blood–brain barrier permeability, elimination half-life, elimination half-lives, and potential for oral administration, oral bioavailability. Ligands Agonists ;Peptide * Oxytocin * Demoxytocin * Carbetocin * Lipo-oxytocin-1 * Merotocin ;Non-peptide agonists * LIT-001 — improved social deficits in mice; non-selective over vasopressin receptors * TC OT 39 – non-selective over vasopressin receptors * WAY-267,464 – anxiolytic in mice; possibly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxytocin With Labels
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. Present in animals since early stages of evolution, in humans it plays roles in behavior that include Human bonding, social bonding, love, reproduction, childbirth, and the Postpartum period, period after childbirth. Oxytocin is released into the bloodstream as a hormone in response to Human sexual activity, sexual activity and during childbirth. It is also available in Oxytocin (medication), pharmaceutical form. In either form, oxytocin stimulates uterine contractions to speed up the process of childbirth. In its natural form, it also plays a role in maternal bonding and lactation, milk production. Production and secretion of oxytocin is controlled by a positive feedback mechanism, where its initial release stimulates production and release of further oxytocin. For example, when oxytocin is released during a contraction of the uterus at the start of c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
