HNK Gorica Managers
HNK may refer to: * Croatian National Corpus (Croatian: ') * Croatian National Theatre (other) (Croatian: ') * ''Fist of the North Star'' (Japanese: ') a manga and its franchise * Honokiol, a lignan * Hydroxynorketamine, a metabolite of ketamine * ''Land of the Lustrous is a Japanese manga series written and illustrated by . It was published by Kodansha in ''Monthly Afternoon'' magazine from October 2012 to April 2024, with its chapters collected in thirteen volumes. Set in a world inhabited by Lustrous� ...

Croatian National Corpus
Croatian National Corpus (, ''HNK'') is the biggest and the most important corpus of Croatian. Its compilation started in 1998 at the Institute of Linguistics of the Faculty of Humanities and Social Sciences, University of Zagreb following the ideas ofMarko Tadić The theoretical foundations and the expression of the need for a general-purpose, representative and multi-million corpus of Croatian started to appear even earlier. The Croatian National Corpus is compiled from selected texts written in Croatian covering all fields, topics, genres and styles: from literary and scientific texts to text-books, newspaper, user-groups and chat rooms. The initial composition was divided in two constituents: # ''30-million corpus of contemporary Croatian'' (30m) where samples from texts from 1990 on were included. The criteria for inclusion of text samples were: written by native speakers, different fields, genres and topics. Translated text or poetry were excluded. # ''Croatian Electronic Tex ...
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Croatian National Theatre (other)
Croatian National Theatre () is the official name of several state-funded theatre houses in Croatia. Each one is commonly referred to by the Croatian-language initialism HNK. The four theatre houses in biggest cities (Zagreb, Split, Rijeka and Osijek) are considered premier theatre and opera houses in the country. In addition, there are three other smaller theatres carrying that name in Croatia (in Šibenik, Varaždin and Zadar) and one in Bosnia and Herzegovina (in Mostar). Hence it may refer to: * Croatian National Theatre in Rijeka ("HNK Zajc" or "HNK Rijeka"), located in Rijeka; not to be confused with HNK Rijeka (the football club) * Croatian National Theatre in Mostar ("HNK Mostar"), a theatre located in Mostar, home to the largest population of Croats in Bosnia and Herzegovina * Croatian National Theatre in Osijek ("HNK Osijek"), a theatre building in Osijek, capital of the Croatian region of Slavonia * Croatian National Theatre in Šibenik ("HNK Šibenik"), located in Šibeni ...
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Fist Of The North Star
is a Japanese manga series written by Buronson and illustrated by Tetsuo Hara. It was serialized in Shueisha's manga magazine ''Weekly Shōnen Jump'' for 245 issues published from 1983 to 1988 and initially collected in 27 volumes under the Jump Comics imprint. Set on a post-apocalyptic Earth after a nuclear war, the story centers on a warrior named Kenshiro, the successor of a deadly martial art known as ''Hokuto Shinken'', which gives him the ability to kill his opponents by striking their secret vital points, which often results in an exceptionally violent and gory death. Kenshiro dedicates his life to fighting against the various gangs, bandits, and warlords who threaten the lives of the defenseless and innocent, as well as rival martial artists. ''Fist of the North Star'' was adapted into two anime television series produced by Toei Animation, which together aired on Fuji TV and its affiliates from 1984 through 1988, comprising a combined total of 152 episo ...
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Honokiol
Honokiol is a lignan Bark isolate, isolated from the bark, seed cones, and leaves of trees belonging to the genus ''Magnolia''. It has been identified as one of the chemical compounds in some traditional Eastern herbal medicines along with magnolol, 4-O-methylhonokiol, and obovatol. Honokiol, a compound with a spicy odor extracted from various ''Magnolia'' species worldwide, including those native to the Southeastern United States and Mexico, can readily cross the blood-brain and cerebrospinal fluid barriers, making it a highly bioavailable and potentially effective therapeutic agent. Honokiol is a small, hydrophobic neolignan biphenol structurally similar to propofol that can be purified efficiently from its isomer magnolol using advanced chromatography techniques such as magnolol acetonide protection followed by flash chromatography or high-capacity high-speed countercurrent chromatography. Extracts from the bark and seed cones of ''Magnolia'' trees have been traditionally used ...
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Hydroxynorketamine
Hydroxynorketamine (HNK), or 6-hydroxynorketamine, is a minor metabolite of the anesthetic, dissociative, and antidepressant drug ketamine. It is formed by hydroxylation of the intermediate norketamine, another metabolite of ketamine. As of late 2019, (2''R'',6''R'')-HNK is in clinical trials for the treatment of depression. The major metabolite of ketamine is norketamine (80%). Norketamine is secondarily converted into 4-, 5-, and 6-hydroxynorketamines (15%), mainly HNK (6-hydroxynorketamine). Ketamine is also transformed into hydroxyketamine (5%). As such, bioactivated HNK comprises less than 15% of a dose of ketamine. Pharmacology In contrast to ketamine and norketamine, HNK is inactive as an anesthetic and psychostimulant. In accordance, it has only very weak affinity for the NMDA receptor (Ki = 21.19 μM and > 100 μM for (2''S'',6''S'')-HNK and (2''R'',6''R'')-HNK, respectively). However, HNK does still show biological activity, having been found to act as a potent and s ...
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