Epstein–Barr Virus
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Epstein–Barr Virus
The Epstein–Barr virus (EBV), also known as human herpesvirus 4 (HHV-4), is one of the nine known Herpesviridae#Human herpesvirus types, human herpesvirus types in the Herpesviridae, herpes family, and is one of the most common viruses in humans. EBV is a DNA virus#Double-stranded DNA viruses, double-stranded DNA virus. EBV is the first identified oncogenic virus, a virus that can cause cancer. EBV establishes permanent infection in human B cells. It uncommonly causes infectious mononucleosis and is also tightly linked to many Malignancy, malignant diseases (cancers and autoimmune diseases). Various vaccine formulations have been tested in animals and humans; however, none of them were able to prevent EBV infection, thus, no vaccine has been approved to date. Infectious mononucleosis ("mono" or "glandular fever"), is characterized by extreme fatigue, fever, sore throat, and swollen lymph nodes. EBV is also associated with various non-malignant, premalignant, and malignant E ...
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Electron Micrograph
A micrograph is an image, captured photographically or digitally, taken through a microscope or similar device to show a magnify, magnified image of an object. This is opposed to a macrograph or photomacrograph, an image which is also taken on a microscope but is only slightly magnified, usually less than 10 times. Micrography is the practice or art of using microscopes to make photographs. A photographic micrograph is a photomicrograph, and one taken with an electron microscope is an electron micrograph. A micrograph contains extensive details of microstructure. A wealth of information can be obtained from a simple micrograph like behavior of the material under different conditions, the phases found in the system, failure analysis, grain size estimation, elemental analysis and so on. Micrographs are widely used in all fields of microscopy. Types Photomicrograph A light micrograph or photomicrograph is a micrograph prepared using an optical microscope, a process referred to ...
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Hodgkin Lymphoma
Hodgkin lymphoma (HL) is a type of lymphoma in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the lymph nodes. The condition was named after the English physician Thomas Hodgkin, who first described it in 1832. Symptoms may include fever, night sweats, and weight loss. Often, non-painful lymphadenopathy, enlarged lymph nodes occur in the neck, under the arm, or in the groin. Persons affected may feel tired or be itchy. The two major types of Hodgkin lymphoma are classic Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. About half of cases of Hodgkin lymphoma are due to Epstein–Barr virus (EBV) and these are generally the classic form. Other risk factors include a family history of the condition and having HIV/AIDS. Diagnosis is conducted by confirming the presence of cancer and identifying Reed–Sternberg cells in lymph node biopsies. The virus-posi ...
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Autoimmune Disease
An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms. It is estimated that there are more than 80 recognized autoimmune diseases, with recent scientific evidence suggesting the existence of potentially more than 100 distinct conditions. Nearly any body part can be involved. Autoimmune diseases are a separate class from autoinflammatory diseases. Both are characterized by an immune system malfunction which may cause similar symptoms, such as rash, swelling, or fatigue, but the cardinal cause or mechanism of the diseases is different. A key difference is a malfunction of the innate immune system in autoinflammatory diseases, whereas in autoimmune diseases there is a malfunction of the adaptive immune system. Symptoms of autoimmune diseases can significantly vary, primarily based on the specific type of the d ...
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Clinical Pediatrics
''Clinical Pediatrics'' is a peer-reviewed medical journal of pediatrics that was established in 1962. It is published monthly by SAGE Publications and edited by Brian S. Carter. Scope ''Clinical Pediatrics'' is a medical journal that seeks to publish and to accessible information on a variety of child-centered care topics including those of a clinical, scientific, behavioral, educational, or ethical nature. Abstracting and indexing ''Clinical Pediatrics'' is abstracted and indexed in, among other databases: SCOPUS, and the Social Sciences Citation Index. According to the ''Journal Citation Reports'', its 2018 impact factor is 1.383, ranking it 78 out of 125 journals in the category 'Pediatrics'. References # "Journals Ranked by Impact: Pediatrics". ''2017 Journal Citation Reports''. Web of Science (Science ed.). Clarivate Analytics Clarivate Plc is a British-American publicly traded analytics company that operates a collection of subscription-based services, in ...
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Acute Cerebellar Ataxia Of Childhood
Acute cerebellar ataxia of childhood is a childhood condition characterized by an unsteady gait, most likely secondary to an autoimmune response to infection, drug induced or paraneoplastic. The most common viruses causing acute cerebellar ataxia are chickenpox virus and Epstein–Barr virus, leading to a childhood form of post viral cerebellar ataxia. It is a diagnosis of exclusion. Signs and symptoms Acute cerebellar ataxia usually follows 2–3 weeks after an infection. Onset is abrupt. Vomiting may be present at the onset but fever and nuchal rigidity characteristically are absent. Horizontal nystagmus is present in approximately 50% of cases. * Truncal ataxia with deterioration of gait * Slurred speech and nystagmus * Afebrile Cause Possible causes of acute cerebellar ataxia include varicella infection, as well as infection with influenza, Epstein–Barr virus, Coxsackie virus, Echo virus or mycoplasma. Diagnosis Acute Cerebellar ataxia is a diagnosis of exclusion. ...
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BioMed Research International
''BioMed Research International'' is a peer-reviewed open access scientific journal covering all aspects of biomedical sciences. It was established in 2001 as the ''Journal of Biomedicine and Biotechnology'' with Abdelali Haoudi as first editor-in-chief (until 2008). The journal obtained its current title in 2013 and is published by Hindawi Publishing Corporation. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2014 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 1.579, and in 2016 its ranking was 65/158 of Biotechnology & Applied Microbiology. References External links * Hindawi Publishing Corporation academic journals Academic journals established in 2001 Open acc ...
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Alice In Wonderland Syndrome
Alice in Wonderland Syndrome (AIWS), also known as Todd's Syndrome or Dysmetropsia, is a neurological disorder that distorts perception. People with this syndrome may experience distortions in their visual perception of objects, such as appearing smaller ( micropsia) or larger (macropsia), or appearing to be closer ( pelopsia) or farther ( teleopsia) than they are. Distortion may also occur for senses other than vision. The cause of Alice in Wonderland Syndrome is currently not known, but it has often been associated with migraines, head trauma, or viral encephalitis caused by Epstein–Barr Virus Infection. It is also theorized that AIWS can be caused by abnormal amounts of electrical activity, resulting in abnormal blood flow in the parts of the brain that process visual perception and texture. Alice in Wonderland Syndrome is also possible to be experienced temporarily under the use of certain psychoactive drugs. Although there are cases of Alice in Wonderland Syndrome i ...
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Journal Of The National Medical Association
The National Medical Association (NMA) is the largest and oldest organization representing African American physicians and their patients in the United States. As a 501(c)(3) national professional and scientific organization, the NMA represents the interests of over 30,000 African American physicians and their patients, with nearly 112 affiliated societies throughout the nation and U.S. territories. Through its membership, professional growth, community health education, advocacy, research, and collaborations with public and private organizations, the organization is dedicated to enhancing the quality of health among minorities and underprivileged people. Throughout its history, the NMA has primarily focused on health issues related to African Americans and medically underserved populations. However, its principles, goals, initiatives, and philosophy encompass all ethnic groups History During the Jim Crow era in the southern part of the United States, state laws and social custo ...
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Japanese Journal Of Radiology
The Japanese Journal of Radiology (formerly: ''Radiation Medicine'') is a peer-reviewed journal, officially published by the ''Japan Radiological Society''. It provides a forum for the publication of papers documenting recent advances and new developments in the field of radiology Radiology ( ) is the medical specialty that uses medical imaging to diagnose diseases and guide treatment within the bodies of humans and other animals. It began with radiography (which is why its name has a root referring to radiation), but tod ... in medicine and biology. Editor-in-Chief is N Tamaki. ISSN: 1867-1071 (print version) ISSN: 1867-108X (electronic version) References External links * Radiology and medical imaging journals {{med-journal-stub ...
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Lymphoma
Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). The name typically refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, and constantly feeling tired. The enlarged lymph nodes are usually painless. The sweats are most common at night. Many subtypes of lymphomas are known. The two main categories of lymphomas are the non-Hodgkin lymphoma (NHL) (90% of cases) and Hodgkin lymphoma (HL) (10%). Lymphomas, leukemias and myelomas are a part of the broader group of tumors of the hematopoietic and lymphoid tissues. Risk factors for Hodgkin lymphoma include infection with Epstein–Barr virus and a history of the disease in the family. Risk factors for common types of non-Hodgkin lymphomas include autoimmune diseases, HIV/AIDS, infection with human T-lymphotropic virus, immunosuppressant medicat ...
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Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilateria, bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and Coelenterata, diploblasts. It is a structure composed of nervous tissue positioned along the Anatomical_terms_of_location#Rostral,_cranial,_and_caudal, rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain, though precursor structures exist in onychophorans, gastropods and lancelets. The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal ...
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Hairy Leukoplakia
Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised, especially those with human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS). The white lesion, which cannot be scraped off, is benign and does not require any treatment, although its appearance may have diagnostic and prognostic implications for the underlying condition. Depending upon what definition of leukoplakia is used, hairy leukoplakia is sometimes considered a subtype of leukoplakia, or a distinct diagnosis. Signs and symptoms There are no symptoms associated with the lesion itself, although many and varied symptoms and signs may be associated with the underlying cause of immunosuppression. The lesion is a white patch, which almost exclusively occurs on the lateral surfaces of the tongue, although rarely it may occur on the buccal mucosa, so ...
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