Cyclopia Pubescens
Cyclopia (named after the Greek mythology characters cyclopes), also known as alobar holoprosencephaly, is the most extreme form of holoprosencephaly and is a congenital disorder (birth defect) characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses. Signs and symptoms Typically, the nose is either missing or not functional. This deformity (called proboscis) forms above the center eye and is characteristic of a form of cyclopia called rhinencephaly or rhinocephaly. Most such embryos are either naturally miscarried or are stillborn upon delivery. Although cyclopia is rare, several cyclopic human babies are preserved in medical museums (e.g. The Vrolik Museum, Amsterdam, Trivandrum Medical College). Some extreme cases of cyclopia have been documented in farm animals (horses, sheep, pigs, goats, and sometimes chickens). In such case ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Medical Genetics
Medical genetics is the branch of medicine that involves the diagnosis and management of hereditary disorders. Medical genetics differs from human genetics in that human genetics is a field of scientific research that may or may not apply to medicine, while medical genetics refers to the application of genetics to medical care. For example, research on the causes and inheritance of genetic disorders would be considered within both human genetics and medical genetics, while the diagnosis, management, and counselling people with genetic disorders would be considered part of medical genetics. In contrast, the study of typically non-medical phenotypes such as the genetics of eye color would be considered part of human genetics, but not necessarily relevant to medical genetics (except in situations such as albinism). ''Genetic medicine'' is a newer term for medical genetics and incorporates areas such as gene therapy, personalized medicine, and the rapidly emerging new medical specia ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cramp
A cramp is a sudden, involuntary, painful skeletal muscle contraction or overshortening associated with electrical activity. While generally temporary and non-damaging, they can cause significant pain and a paralysis-like immobility of the affected muscle. A cramp usually goes away on its own over several seconds or (sometimes) minutes. Cramps are common and tend to occur at rest, usually at night (nocturnal leg cramps). They are also often associated with pregnancy, physical exercise or overexertion, and age (common in older adults); in such cases, cramps are called idiopathic because there is no underlying pathology. In addition to those benign conditions cramps are also associated with many pathological conditions. Cramp definition is narrower than the definition of muscle spasm: spasms include any involuntary abnormal muscle contractions, while cramps are sustained and painful. True cramps can be distinguished from other cramp-like conditions. Cramps are different from mus ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sweden
Sweden, formally the Kingdom of Sweden, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. It borders Norway to the west and north, and Finland to the east. At , Sweden is the largest Nordic country by both area and population, and is the List of European countries by area, fifth-largest country in Europe. Its capital and largest city is Stockholm. Sweden has a population of 10.6 million, and a low population density of ; 88% of Swedes reside in urban areas. They are mostly in the central and southern half of the country. Sweden's urban areas together cover 1.5% of its land area. Sweden has a diverse Climate of Sweden, climate owing to the length of the country, which ranges from 55th parallel north, 55°N to 69th parallel north, 69°N. Sweden has been inhabited since Prehistoric Sweden, prehistoric times around 12,000 BC. The inhabitants emerged as the Geats () and Swedes (tribe), Swedes (), who formed part of the sea-faring peopl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Glimåkra
Glimåkra is a locality situated in Östra Göinge Municipality, Scania County, Sweden Sweden, formally the Kingdom of Sweden, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. It borders Norway to the west and north, and Finland to the east. At , Sweden is the largest Nordic count ... with 1,383 inhabitants in 2010. The hiking trail Skåneleden's oldest section, SL1 Kust till kust (Coast to coast) passes just north of the village, also featuring a smaller path leading to it from Trollabadet. As hikers approach the village from the east, the landscape transitions from dense woodland to bright and rocky pastures. The path continues westwards towards Osby, passing through the nearby Trollabackarnas forest. References Populated places in Östra Göinge Municipality {{Skåne-geo-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Georges-Louis Leclerc, Comte De Buffon
Georges-Louis Leclerc, Comte de Buffon (; 7 September 1707 – 16 April 1788) was a French Natural history, naturalist, mathematician, and cosmology, cosmologist. He held the position of ''intendant'' (director) at the ''Jardin du Roi'', now called the Jardin des plantes. Buffon's works influenced the next two generations of naturalists, including two prominent French scientists Jean-Baptiste Lamarck and Georges Cuvier. Buffon published thirty-six quarto volumes of his ''Histoire Naturelle'' during his lifetime, with additional volumes based on his notes and further research being published in the two decades following his death. Ernst Mayr wrote that "Truly, Buffon was the father of all thought in natural history in the second half of the 18th century".Mayr, Ernst 1981. ''The Growth of Biological Thought''. Cambridge: Harvard. p 330 Credited with being one of the first naturalists to recognize ecological succession, he was forced by the theology committee at the University of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Marie Marguerite Bihéron
Marie Marguerite Bihéron (17 November 1719 – 18 June 1795) (also known as Marie Catherine Bihéron) was a French anatomist, known for her medical illustrations and wax figure models. Biography Bihéron was the daughter of a French apothecary, born in 1719.Londa L. Schiebinger (1991), ''The Mind Has No Sex? Women in the Origins of Modern Science'', pp.27-30. She studied illustration at the Jardin du RoiAndrew Cunningham, ''The Anatomist Anatomis'd: An Experimental Discipline in Enlightenment Europe'', Ashgate Publishing, 2010, p. and with Madeleine Basseporte, of whom little is known outside of her anatomical drawings, and the memoirs of contemporaries. To procure bodies for her anatomical studies, Bihéron was forced to have them stolen from the military. Frustrated with their rapid putrefaction, Autumn Stanley, ''Mothers and Daughters of Invention: Notes for Revised History of Technology'', Rutgers University Press, 1995. and at the suggestion of Basseporte, Bihéron turne ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mercure De France
The () was originally a French gazette and literary magazine first published in the 17th century, but after several incarnations has evolved as a publisher, and is now part of the Éditions Gallimard publishing group. The gazette was published from 1672 to 1724 (with an interruption in 1674–1677) under the title (sometimes spelled ; 1672–1674) and (1677–1724). The title was changed to in 1724. The gazette was briefly suppressed (under Napoleon) from 1811 to 1815 and ceased publication in 1825. The name was revived in 1890 for both a literary review and (in 1894) a publishing house initially linked with the symbolist movement. Since 1995 has been part of the Éditions Gallimard publishing group. The original ''Mercure galant'' and ''Mercure de France'' The ''Mercure galant'' was founded by the writer Jean Donneau de Visé in 1672. He directed the publication until his death in 1710. The name refers to the god Mercury, the messenger of the gods; the title al ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Colt (horse)
A colt is a young male horse, usually below the age of four years. Description The term "colt" only describes young male horses and is not to be confused with foal, which is a horse of either sex less than one year of age. Similarly, a yearling is a horse of either sex between the ages of one and two. A young female horse is called a filly, and a mare once she is an adult animal. In horse racing, particularly for Thoroughbreds in the United Kingdom, a colt is defined as an uncastrated male from the age of two up to and including the age of four. The term is derived from Proto-Germanic *''kultaz'' ("lump, bundle, offspring") and is etymologically related to "child." An adult male horse, if left intact, is called either a " stallion" if used for breeding, or a horse (sometimes full horse); if castrated, it is called a gelding. In some cases, particularly informal nomenclature, a gelding under four years is still called a colt. A rig or ridgling is a male equine with a reta ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The UK includes the island of Great Britain, the north-eastern part of the island of Ireland, and most of List of islands of the United Kingdom, the smaller islands within the British Isles, covering . Northern Ireland shares Republic of Ireland–United Kingdom border, a land border with the Republic of Ireland; otherwise, the UK is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. It maintains sovereignty over the British Overseas Territories, which are located across various oceans and seas globally. The UK had an estimated population of over 68.2 million people in 2023. The capital and largest city of both England and the UK is London. The cities o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sonic Hedgehog Protein
Sonic hedgehog protein (SHH) is a major signaling molecule of embryonic development in humans and animals, encoded by the ''SHH'' gene. This signaling molecule is key in regulating embryonic morphogenesis in all animals. SHH controls organogenesis and the organization of the central nervous system, limbs, digits and many other parts of the body. Sonic hedgehog is a morphogen that patterns the developing embryo using a concentration gradient characterized by the French flag model. This model has a non-uniform distribution of SHH molecules which governs different cell fates according to concentration. Mutations in this gene can cause holoprosencephaly, a failure of splitting in the cerebral hemispheres, as demonstrated in an experiment using SHH knock-out mice in which the forebrain midline failed to develop and instead only a single fused telencephalic vesicle resulted. Sonic hedgehog still plays a role in differentiation, proliferation, and maintenance of adult tissues. Abn ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |