Collectin Of 43 KDa

	Collectin Of 43 KDa Collectin of 43 kDa (CL-43) is a collectin protein that acts as an antigen recognition protein. When an agent, zymosan, was injected into the tunicate Tunicates are marine invertebrates belonging to the subphylum Tunicata ( ). This grouping is part of the Chordata, a phylum which includes all animals with dorsal nerve cords and notochords (including vertebrates). The subphylum was at one time ... ''Styela plicata'' (causing inflammation), secretion of this collectin was tripled within 96 hours. References Collectins Proteins {{Immunology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Collectin Collectins, col-lectins, (collagen-containing C-type lectins) are a part of the innate immune system. They form a sub-family of collagenous Ca2+-dependent lectins of the family of C-type lectins, which are found in animals. Collectins are soluble pattern recognition receptors (PRRs). Their function is to bind to oligosaccharide structure or lipids that are on the surface of microorganisms. Like other PRRs they bind pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) of oligosaccharide origin. Binding of collectins to microorganisms may trigger elimination of microorganisms by Platelet, aggregation, complement system, complement activation, opsonization, activation of phagocytosis, or inhibition of microbial growth. Other functions of collectins are modulation of inflammation, inflammatory, allergic responses, adaptive immune system and clearance of apoptosis, apoptotic cells. Structure Functionally collectins are trimers. Monomeric subunit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Zymosan Zymosan is a beta-glucan with repeating glucose units connected by β-1,3-glycosidic linkages. It binds to TLR 2 and Dectin-1 ( CLEC7A). Zymosan is a ligand found on the surface of fungi, like yeast. Zymosan is prepared from yeast cell walls and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages, zymosan-induced responses include the induction of proinflammatory cytokines, arachidonate mobilization, protein phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels, suggesting a role for the latter in macrophage activation besides proliferation. It potentiates acute liver damage after galactosamine injection, suggesting that certain types of nonparenchymal cells other than Kupffer cells Kupffer cells, also known as stellate macrophages and Kupffer–Browicz cells, are specialized cells localized in the liver within the lumen of the liver sinusoids and are adhesive to their endoth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Tunicate Tunicates are marine invertebrates belonging to the subphylum Tunicata ( ). This grouping is part of the Chordata, a phylum which includes all animals with dorsal nerve cords and notochords (including vertebrates). The subphylum was at one time called Urochordata, and the term urochordates is still sometimes used for these animals. Despite their simple appearance and very different adult form, their close relationship to the vertebrates is certain. Both groups are chordates, as evidenced by the fact that during their mobile larval stage, tunicates possess a notochord, a hollow dorsal nerve cord, pharyngeal slits, post-anal tail, and an endostyle. They resemble a tadpole. Tunicates are the only chordates that have lost their Myomere, myomeric segmentation, with the possible exception of the seriation of the gill slits. However, Doliolida, doliolids still display segmentation of the muscle bands. Some tunicates live as solitary individuals, but others replicate by budding and be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Collectins Collectins, col-lectins, (collagen-containing C-type lectins) are a part of the innate immune system. They form a sub-family of collagenous Ca2+-dependent lectins of the family of C-type lectins, which are found in animals. Collectins are soluble pattern recognition receptors (PRRs). Their function is to bind to oligosaccharide structure or lipids that are on the surface of microorganisms. Like other PRRs they bind pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) of oligosaccharide origin. Binding of collectins to microorganisms may trigger elimination of microorganisms by aggregation, complement activation, opsonization, activation of phagocytosis, or inhibition of microbial growth. Other functions of collectins are modulation of inflammatory, allergic responses, adaptive immune system and clearance of apoptotic cells. Structure Functionally collectins are trimers. Monomeric subunit consists of four parts: * a cysteine-rich domain a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]