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Clinical Pharmaceutical Scientist
A clinical pharmaceutical scientist (or pharmacist-scientist) is a licensed, practicing pharmacist who also functions as an independent researcher in the Pharmacy#Pharmaceutical sciences, pharmaceutical sciences. Clinical pharmaceutical scientists are a type of clinician scientist, analogous to physician-scientists. Terminology The term clinical pharmaceutical scientist is distinct from the term pharmaceutical scientist, in that a clinical pharmaceutical scientist is a practicing clinical pharmacist involved in science relating to the Drug discovery, discovery and/or Drug development, development of pharmaceuticals, the development of new knowledge improving the use of pharmaceuticals in Medicine#Clinical practice, clinical practice, or any other subfield of Pharmacy#Pharmaceutical sciences, pharmaceutical science (e.g. pharmacoeconomics, pharmacokinetics, outcomes research), while a pharmaceutical scientist need not also be a clinician (pharmacist). Thus, all clinical pharmaceut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process—from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials—to approved vaccine or drug typically takes more than a decade. New chemical entity development Broadly, the process of drug development can be divided into preclinical and clinical work. Pre-clinical New chemical entities (NCEs, also known as new molecular entities or NMEs) are compounds that emerge from the process of drug discovery. These h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Sertürner
Friedrich Wilhelm Adam Sertürner (; 19 June 1783 – 20 February 1841) was a German pharmacist and a pioneer of alkaloid chemistry. He is best known for his discovery of morphine, which he isolated from opium in 1804, and for conducting tests, including on himself, to evaluate its physiological effects. Biography Sertürner was born, the fourth of six children, to Joseph Simon Serdinier and Marie Therese Brockmann on 19 June 1783, in Neuhaus, Holy Roman Empire (now part of Paderborn). The family may have had origins in Sardinia. His father called himself an ''architectus'', serving surveyor and engineer to the prince bishop. After his father died, he became a pharmacist's apprentice at the Cramersche Hofapotheke in Paderborn. He completed the apprenticeship in four years and passed the qualifying examination on August 2, 1803. Sertürner worked on the isolation of morphine from opium from 1804. He called the isolated alkaloid "morphium" after the Greek god of dreams, Morpheus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
History Of Pharmacy
The history of pharmacy as a modern and independent science dates back to the first third of the 19th century. Before then, pharmacy evolved from antiquity as part of medicine. Before the advent of pharmacists, there existed apothecaries that worked alongside priests and physicians in regard to patient care. Prehistoric pharmacy Paleopharmacological studies attest to the use of medicinal plants in pre-history. For example, herbs were discovered in the Shanidar Cave, and remains of the areca nut (''Areca catechu)'' in the Spirit Cave. Prehistoric man learned pharmaceutical techniques through instinct, by watching birds and beasts, and using cool water, leaves, dirt, or mud as a soothing agent. Ancient Era Mesopotamia and Egypt Sumerian cuneiform tablets record prescriptions for medicine. Ancient Egyptian pharmacological knowledge was recorded in various papyri, such as the ''Ebers Papyrus'' of 1550 BC and the ''Edwin Smith Papyrus'' of the 16th century BC. The very begin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Misuse
Substance misuse, also known as drug misuse or, in older vernacular, substance abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a form of substance-related disorder, differing definitions of drug misuse are used in public health, medical, and criminal justice contexts. In some cases, criminal or anti-social behavior occurs when some persons are under the influence of a drug, and may result in long-term personality changes in individuals which may also occur. In addition to possible physical, social, and psychological harm, the use of some drugs may also lead to criminal penalties, although these vary widely depending on the local jurisdiction.. Drugs most often associated with this term include alcohol, amphetamines, barbiturates, benzodiazepines, cannabis, cocaine, hallucinogens, methaqualone, and opioids. The exact cause of substance abuse is sometimes clear, but there are two predominant theories: either a genetic pre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prescription Drug
A prescription drug (also prescription medication, prescription medicine or prescription-only medication) is a pharmaceutical drug that is permitted to be dispensed only to those with a medical prescription. In contrast, over-the-counter drugs can be obtained without a prescription. The reason for this difference in substance control is the potential scope of misuse, from drug abuse to practising medicine without a license and without sufficient education. Different jurisdictions have different definitions of what constitutes a prescription drug. In North America, , usually printed as "Rx", is used as an abbreviation of the word "prescription". It is a contraction of the Latin word "''recipe''" (an imperative form of "recipere") meaning "take". Prescription drugs are often dispensed together with a monograph (in Europe, a Patient Information Leaflet or PIL) that gives detailed information about the drug. The use of prescription drugs has been increasing since the 1960s. Regul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacy School
The basic requirement for pharmacists to be considered for registration is often an undergraduate or postgraduate pharmacy degree from a recognized university. In many countries, this involves a four- or five-year course to attain a bachelor of pharmacy or Master of Pharmacy, master of pharmacy degree. In the United States since 2003, students must complete a doctor of pharmacy degree to become a licensed pharmacist, with a similar requirement being introduced in some other countries such as Canada and France. The doctor of pharmacy degree usually requires completion of four years at an accredited college of pharmacy after an undergraduate degree or other approved courses. To practice as a pharmacist, registration with the country, state, or province's regulatory agency is required. There is often a requirement for the pharmacy graduate to have completed a certain number of hours of experience in a pharmacy under the supervision of a registered pharmacist. If the regulator ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Care In The United States
Healthcare in the United States is largely provided by private sector healthcare facilities, and paid for by a combination of public programs, private insurance, and out-of-pocket payments. The U.S. is the only developed country without a system of universal healthcare, and a significant proportion of its population lacks health insurance. The United States spends more on healthcare than any other country, both in absolute terms and as a percentage of GDP; however, this expenditure does not necessarily translate into better overall health outcomes compared to other developed nations. In 2022, the United States spent approximately 17.8% of its Gross Domestic Product (GDP) on healthcare, significantly higher than the average of 11.5% among other high-income countries. Coverage varies widely across the population, with certain groups, such as the elderly, disabled and low-income individuals receiving more comprehensive care through government programs such as Medicaid and Medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Pharmacology
Clinical pharmacology is "that discipline that teaches, does research, frames policy, gives information and advice about the actions and proper uses of medicines in humans and implements that knowledge in clinical practice". Clinical pharmacology is inherently a translational discipline underpinned by the basic science of pharmacology, engaged in the experimental and observational study of the disposition and effects of drugs in humans, and committed to the translation of science into evidence-based therapeutics. It has a broad scope, from the discovery of new target molecules to the effects of drug usage in whole populations. The main aim of clinical pharmacology is to generate data for optimum use of drugs and the practice of 'evidence-based medicine'. Clinical pharmacologists have medical and scientific training that enables them to evaluate evidence and produce new data through well-designed studies. Clinical pharmacologists must have access to enough patients for clinical c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinician
A clinician is a health care professional typically employed at a skilled nursing facility or clinic. Clinicians work directly with patients rather than in a laboratory, community health setting or in research. A clinician may diagnose, treat and care for patients as a psychologist, clinical pharmacist, clinical scientist, nurse, occupational therapist, speech-language pathologist, physiotherapist, dentist, optometrist, physician assistant, clinical officer, physician, paramedic, or chaplain. Clinicians undergo and take comprehensive training and exams to be licensed and some complete graduate degrees (master's or doctorates) in their field of expertise. The main function of a clinician is to manage a sick person in order to cure their illness, reduce pain and suffering, and extend life considering the impact of illness upon the patient and their family as well as other social factors. See also * List of healthcare occupations A listing of health care professions by m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Outcomes Research
Outcomes research is a branch of public health research which studies the end results (wikt:outcome#Noun, outcomes) of the structure and processes of the health care system on the health and well-being of patients and populations. According to one medical outcomes and guidelines source book - 1996, ''Outcomes research'' includes health services research that focuses on identifying variations in medical procedures and associated health outcomes. Though listed as a synonym for the National Library of Medicine Medical Subject Headings, MeSH term "Outcome Assessment (Health Care)", outcomes research may refer to both health services research and healthcare outcomes assessment, which aims at health technology assessment, decision making, and policy analysis through systematic evaluation of quality of care, access, and effectiveness. Description Outcomes research is applied to clinical and population based research that seeks to study and optimize the end results of healthcare in terms o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacokinetics
Pharmacokinetics (from Ancient Greek ''pharmakon'' "drug" and ''kinetikos'' "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration. The substances of interest include any chemical xenobiotic such as pharmaceutical drugs, pesticides, food additives, cosmetics, etc. It attempts to analyze chemical metabolism and to discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics is based on mathematical modeling that places great emphasis on the relationship between drug plasma concentration and the time elapsed since the drug's administration. Pharmacokinetics is the study of how an organism affects the drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
