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Chronic Mountain Sickness
Chronic mountain sickness (CMS) is a disease in which the proportion of blood volume that is occupied by red blood cells increases ( polycythaemia) and there is an abnormally low level of oxygen in the blood (hypoxemia). CMS typically develops after extended time living at high altitude (over ). It is most common amongst native populations of high altitude nations. The most frequent symptoms of CMS are headache, dizziness, tinnitus, breathlessness, palpitations, sleep disturbance, fatigue, loss of appetite, confusion, cyanosis, and dilation of veins. CMS was first described in 1925 by Carlos Monge Medrano, a Peruvian doctor who specialised in diseases of high altitude. While acute mountain sickness is experienced shortly after ascent to high altitude, chronic mountain sickness may develop only after many years of living at high altitude. In medicine, high altitude is defined as over , but most cases of CMS occur at over . It has recently been correlated with increased expression ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emergency Medicine
Emergency medicine is the medical speciality concerned with the care of illnesses or injuries requiring immediate medical attention. Emergency physicians (often called “ER doctors” in the United States) continuously learn to care for unscheduled and undifferentiated patients of all ages. As first-line providers, in coordination with Emergency Medical Services, they are primarily responsible for initiating resuscitation and stabilization and performing the initial investigations and interventions necessary to diagnose and treat illnesses or injuries in the acute phase. Emergency physicians generally practise in hospital emergency departments, pre-hospital settings via emergency medical services, and intensive care units. Still, they may also work in primary care settings such as urgent care clinics. Sub-specializations of emergency medicine include; disaster medicine, medical toxicology, point-of-care ultrasonography, critical care medicine, emergency medical service ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cor Pulmonale
Pulmonary heart disease, also known as cor pulmonale, is the enlargement and failure of the right ventricle of the heart as a response to increased vascular resistance (such as from pulmonic stenosis) or high blood pressure in the lungs. Chronic pulmonary heart disease usually results in right ventricular hypertrophy (RVH), whereas acute pulmonary heart disease usually results in dilatation. Hypertrophy is an adaptive response to a long-term increase in pressure. Individual muscle cells grow larger (in thickness) and change to drive the increased contractile force required to move the blood against greater resistance. Dilatation is a stretching (in length) of the ventricle in response to acute increased pressure. To be classified as pulmonary heart disease, the cause must originate in the pulmonary circulation system; RVH due to a systemic defect is not classified as pulmonary heart disease. Two causes are vascular changes as a result of tissue damage (e.g. disease, hypoxic in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerro De Pasco
Cerro de Pasco is a city in central Peru, located at the top of the Andean mountains. It is the capital of the Pasco region, and an important mining center. At elevation, it is one of the highest cities in the world, and the highest or the second highest city with over 50,000 inhabitants, with elevation reaching up to in the Yanacancha area. It is connected by road and by rail to the capital Lima, away. Mining center Cerro de Pasco became one of the world's richest silver producing areas after silver was discovered there in 1630. It is still an active mining center. The Spanish mined the rich Cerro de Pasco silver-bearing oxide ore deposits since colonial times. Sulfide minerals are more common in the Atacocha district however. Francisco Uville arranged for steam engines made by Richard Trevithick of Cornwall, England, to be installed in Cerro de Pasco in 1816 to pump water from the mines and allow lower levels to be reached. However, fighting in the Peruvian War of I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
La Paz
La Paz (), officially known as Nuestra Señora de La Paz (Spanish pronunciation: ), is the seat of government of the Plurinational State of Bolivia. With an estimated 816,044 residents as of 2020, La Paz is the third-most populous city in Bolivia. Its metropolitan area, which is formed by La Paz, El Alto, Achocalla, Viacha, and Mecapaca makes up the second most populous urban area in Bolivia, with a population of 2.0 million, after Santa Cruz de la Sierra with a population of 2.3 million. It is also the capital of the La Paz Department. The city, in west-central Bolivia southeast of Lake Titicaca, is set in a canyon created by the Choqueyapu River. It is in a bowl-like depression, part of the Amazon basin, surrounded by the high mountains of the Altiplano. Overlooking the city is the towering, triple-peaked Illimani. Its peaks are always snow-covered and can be seen from many parts of the city. At an elevation of roughly above sea level, La Paz is the highes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Han Chinese
The Han Chinese () or Han people (), are an East Asian ethnic group native to China. They constitute the world's largest ethnic group, making up about 18% of the global population and consisting of various subgroups speaking distinctive varieties of the Chinese language. The estimated 1.4 billion Han Chinese people, worldwide, are primarily concentrated in the People's Republic of China (including Mainland China, Hong Kong and Macau) where they make up about 92% of the total population. In the Republic of China (Taiwan), they make up about 97% of the population. People of Han Chinese descent also make up around 75% of the total population of Singapore. Originating from Northern China, the Han Chinese trace their cultural ancestry to the Huaxia, the confederation of agricultural tribes living along the Yellow River. This collective Neolithic confederation included agricultural tribes Hua and Xia, hence the name. They settled along the Central Plains around the middle a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tibetan Plateau
The Tibetan Plateau (, also known as the Qinghai–Tibet Plateau or the Qing–Zang Plateau () or as the Himalayan Plateau in India, is a vast elevated plateau located at the intersection of Central, South and East Asia covering most of the Tibet Autonomous Region, most of Qinghai, western half of Sichuan, Southern Gansu provinces in Western China, southern Xinjiang, Bhutan, the Indian regions of Ladakh and Lahaul and Spiti (Himachal Pradesh) as well as Gilgit-Baltistan in Pakistan, northwestern Nepal, eastern Tajikistan and southern Kyrgyzstan. It stretches approximately north to south and east to west. It is the world's highest and largest plateau above sea level, with an area of (about five times the size of Metropolitan France). With an average elevation exceeding and being surrounded by imposing mountain ranges that harbor the world's two highest summits, Mount Everest and K2, the Tibetan Plateau is often referred to as "the Roof of the World". The Tibetan Platea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
East African Mountains
The East African mountains are a mountain region in the African Great Lakes, within Kenya, Uganda, Tanzania, Democratic Republic of the Congo, Rwanda and Burundi. Location and description The mountains are related to the East African Rift, and are in two chains, the Western Rift includes the Virunga Mountains, Mitumba Mountains, and the Rwenzori Range, while the mountains to the east include the largest peaks in Africa: the snow-covered Mount Kilimanjaro (5,895m, 19,340 ft), and Mount Kenya (5,199m, 17,058 ft). Other mountains in the Eastern Rift area include Mount Elgon in Kenya and Uganda. All but the Ruwenzori are of volcanic origin. The weather at the highest elevations is often cold and wet. Fauna The mountains are rich in wildlife, including animals who migrate to higher altitudes during the hot season in the surrounding savanna. The mountains are home to a number of endemic bird species such as Hinde's babbler which lives only on Mount Kenya. Threats and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prevalence Rate
In epidemiology, prevalence is the proportion of a particular population found to be affected by a medical condition (typically a disease or a risk factor such as smoking or seatbelt use) at a specific time. It is derived by comparing the number of people found to have the condition with the total number of people studied and is usually expressed as a fraction, a percentage, or the number of cases per 10,000 or 100,000 people. Prevalence is most often used in questionnaire studies. Difference between prevalence and incidence Prevalence is the number of disease cases ''present ''in a particular population at a given time, whereas incidence is the number of new cases that ''develop '' during a specified time period. Prevalence answers "How many people have this disease right now?" or "How many people have had this disease during this time period?". Incidence answers "How many people acquired the disease uring a specified time period". However, mathematically, prevalence is propor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erythropoietin
Erythropoietin (; EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow. Low levels of EPO (around 10 mU/mL) are constantly secreted in sufficient quantities to compensate for normal red blood cell turnover. Common causes of cellular hypoxia resulting in elevated levels of EPO (up to 10 000 mU/mL) include any anemia, and hypoxemia due to chronic lung disease. Erythropoietin is produced by interstitial fibroblasts in the kidney in close association with the peritubular capillary and proximal convoluted tubule. It is also produced in perisinusoidal cells in the liver. Liver production predominates in the fetal and perinatal period; renal production predominates in adulthood. It is homologous with thrombopoietin. Exogenous erythropoietin, recombinant human erythropoietin (rhEPO) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbonic Anhydrase Inhibitor
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, idiopathic intracranial hypertension, neurological disorders, or osteoporosis. Medical uses Carbonic anhydrase inhibitors are primarily used for the treatment of glaucoma. They may also be used to treat seizure disorder and acute mountain sickness. Because they encourage solubilization and excretion of uric acid, they can be used in the treatment of gout. Glaucoma Acetazolamide is an inhibitor of carbonic anhydrase. It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lower ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetazolamide
Acetazolamide, sold under the trade name Diamox among others, is a medication used to treat glaucoma, epilepsy, altitude sickness, periodic paralysis, idiopathic intracranial hypertension (raised brain pressure of unclear cause), urine alkalinization, and heart failure. It may be used long term for the treatment of open angle glaucoma and short term for acute angle closure glaucoma until surgery can be carried out. It is taken by mouth or injection into a vein. Acetazolamide is a first generation carbonic anhydrase inhibitor and it decreases the ocular fluid and osmolality in the eye to decrease intraocular pressure. Common side effects include numbness, ringing in the ears, loss of appetite, vomiting, and sleepiness. It is not recommended in those with significant kidney problems, liver problems, or who are allergic to sulfonamides. Acetazolamide is in the diuretic and carbonic anhydrase inhibitor families of medication. It works by decreasing the formation of hyd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phlebotomy
Phlebotomy is the process of making a puncture in a vein, usually in the arm, with a cannula for the purpose of drawing blood. The procedure itself is known as a venipuncture, which is also used for intravenous therapy. A person who performs a phlebotomy is called a ''phlebotomist'', although most doctors, nurses, and other technicians can also carry out a phlebotomy. In contrast, phlebectomy is the removal of a vein. Phlebotomies that are carried out in the treatment of some blood disorders are known as '' therapeutic phlebotomies''. The average volume of whole blood drawn in a therapeutic phlebotomy to an adult is 1 unit (450-500 ml) weekly to once every several months, as needed. Etymology From grc, φλεβοτομία ( – 'blood vessel, vein' + 'cutting'), via fro, flebothomie (modern French ). Phlebotomies Phlebotomies are carried out by phlebotomists – people trained to draw blood mostly from veins for clinical or medical testing, transfusions, donations, or rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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