Charles Heidelberger
Charles Heidelberger (December 23, 1920 – January 18, 1983) was a cancer researcher who developed and patented an anticancer drug called 5-Fluorouracil that remains widely used against cancers of the stomach, colon and breast. He was also director of basic research at the University of Southern California's Comprehensive Cancer Center. He received an American Cancer Society National Award in 1974. Heidelberger served on editorial boards of various scientific journals: ''Cancer Research'', '' Molecular Pharmacology'', '' Biochemical Pharmacology'', the ''International Journal of Cancer'', ''In Vitro'', and the ''Journal of Medicinal Chemistry''. He served as director for Basic Research of the USC Cancer Center, and was a Distinguished Professor at the University of Southern California. His former home in Madison, Wisconsin, now known as the Dr. Charles and Judith Heidelberger House, is listed on the National Register of Historic Places. Notable awards and distinctions Heidelbe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fluorouracil
Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer. As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts. Side effects of use by injection are common. They may include inflammation of the mouth, loss of appetite, low blood cell counts, hair loss, and inflammation of the skin. When used as a cream, irritation at the site of application usually occurs. Use of either form in pregnancy may harm the fetus. Fluorouracil is in the antimetabolite and pyrimidine analog families of medications. How it works is not entirely clear, but it is believed to involve blocking the action of thymidylate synthase and thus stopping the production of DNA. Fluorouracil was patented in 1956 and came into medical u ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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New York City
New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive with a respective county. The city is the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the United States by both population and urban area. New York is a global center of finance and commerce, culture, technology, entertainment and media, academics, and scientific output, the arts and fashion, and, as home to the headquarters of the United Nations, international diplomacy. With an estimated population in 2024 of 8,478,072 distributed over , the city is the most densely populated major city in the United States. New York City has more than double the population of Los Angeles, the nation's second-most populous city. [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harvard University Alumni
The list of Harvard University alumni includes notable graduates, professors, and administrators affiliated with Harvard University. For a list of notable non-graduates of Harvard, see the list of Harvard University non-graduate alumni. For a list of Harvard's presidents, see President of Harvard University. Eight Presidents of the United States have graduated from Harvard University: John Adams, John Quincy Adams, Rutherford B. Hayes, John F. Kennedy, Franklin Delano Roosevelt, Theodore Roosevelt, George W. Bush, and Barack Obama. Bush graduated from Harvard Business School, Hayes and Obama from Harvard Law School, and the others from Harvard College. Over 150 Nobel Prize winners have been associated with the university as alumni, researchers or faculty. Nobel laureates Pulitzer Prize winners ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Members Of The United States National Academy Of Sciences
Member may refer to: * Military jury, referred to as "Members" in military jargon * Element (mathematics), an object that belongs to a mathematical set * In object-oriented programming, a member of a class ** Field (computer science), entries in a database ** Member variable, a variable that is associated with a specific object * Limb (anatomy), an appendage of the human or animal body ** Euphemism for penis * Structural component of a truss, connected by nodes * User (computing), a person making use of a computing service, especially on the Internet * Member (geology), a component of a geological formation * Member of parliament * The Members, a British punk rock band * Meronymy, a semantic relationship in linguistics * Church membership, belonging to a local Christian congregation, a Christian denomination and the universal Church * Member, a participant in a club or learned society A learned society ( ; also scholarly, intellectual, or academic society) is an organizatio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1983 Deaths
1983 saw both the official beginning of the Internet and the first mobile cellular telephone call. Events January * January 1 – The migration of the ARPANET to Internet protocol suite, TCP/IP is officially completed (this is considered to be the beginning of the true Internet). * January 6 – Pope John Paul II appoints a bishop over the Czechoslovak exile community, which the ''Rudé právo'' newspaper calls a "provocation." This begins a year-long disagreement between the Czechoslovak Socialist Republic and the Vatican City, Vatican, leading to the eventual restoration of diplomatic relations between the two states. * January 14 – The head of Bangladesh's military dictatorship, Hussain Muhammad Ershad, announces his intentions to "turn Bangladesh into an Islamic state." * January 18 – United States Secretary of the Interior, U.S. Secretary of the Interior James G. Watt makes controversial remarks blaming poor living conditions on Indian reservation, Native American re ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1920 Births
Events January * January 1 ** Polish–Soviet War: The Russian Red Army increases its troops along the Polish border from 4 divisions to 20. ** Kauniainen in Finland, completely surrounded by the city of Espoo, secedes from Espoo as its own market town. * January 7 – Russian Civil War: The forces of White movement, Russian White Admiral Alexander Kolchak surrender in Krasnoyarsk; the Great Siberian Ice March ensues. * January 10 ** The Treaty of Versailles takes effect, officially ending World War I. ** The League of Nations Covenant enters into force. On January 16, the organization holds its first council meeting, in Paris. * January 11 – The Azerbaijan Democratic Republic is recognised de facto by European powers in Palace of Versailles, Versailles. * January 13 – ''The New York Times'' Robert H. Goddard#Publicity and criticism, ridicules American rocket scientist Robert H. Goddard, which it will rescind following the launch of Apollo 11 in 1969. * Janua ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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American Cancer Researchers
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States Native Americans (also called American Indians, First Americans, or Indigenous Americans) are the Indigenous peoples of the Americas, Indigenous peoples of the United States, particularly of the Contiguous United States, lower 48 states and A ..., indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headqua ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Wisconsin
A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's Etymology, etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is focused on the diagnosis of cancer in a person, therapy (e.g., surgery, chemotherapy, radiotherapy and other modalities), monitoring of patients after treatment, palliative care of people with advanced-stage cancers, Ethics, ethical questions surrounding cancer care, Screening (medicine), screening of patients, and the study of cancer treatments through clinical research. An oncologist typically focuses on a specialty area in cancer treatment, such as surgery, Radiation therapy, radiation, gynecology, gynecologic oncology, geriatrics, geriatric oncology, pediatrics, pediatric oncology, and various organ-specific disciplines (breast, brain, liver, among others). The exp ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes Physical property, physical and Chemical property, chemical properties, and evaluation of Reactivity (chemistry), chemical reactivity to understand their behavior. The study of organic reactions includes the organic synthesis, chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical (in silico) study. The range of chemicals studied chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harvard
Harvard University is a private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of colonial-era Massachusetts Bay Colony. While never formally affiliated with any denomination, Harvard trained Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston elite. Following the American Civil War, under Harvard president Charles William Eliot's long tenure from 1869 to 1909, Harvard developed multiple professional schools, which transfo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |