Centre For Geogenetics
The Centre for Geogenetics is a Danish Basic Research Centre of Excellence (Grundforskningscenter) which officially opened in September 2010. It is located at the Natural History Museum of Denmark, University of Copenhagen and financed by the Danish National Research Foundation. Research program The centre originally focused on questions related to evolutionary biology and geology, but has expanded into various health and disease related topics. The program currently includes: * How did the first human colonization of the Americas happen. The centre addresses the timing, routes and origin of these questions * Why, how and when did the timing, nature and causes of the Late Quaternary megafaunal extinctions happen * Origins, intermixing and migration routes of humans into the New World’s northern extremes (North America, Greenland) * Providing long-term insights into the response of polar ecosystems and coastal sea ice cover to global warming * Advance our understanding of the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Natural History Museum Of Denmark
The Natural History Museum of Denmark () is a natural history museum located in Copenhagen, Denmark. It is affiliated with the University of Copenhagen The museum became an organizational entity in 2004 with the merger of Copenhagen's Zoological Museum, Geological Museum, Botanical Museum and Central Library, and Botanical Gardens.(Zoological Museum, Geological Museum, Botanical Museum and Botanical Garden). The collections of the Natural History Museum Denmark belong to the Danish state and the museum has the responsibility, under the Museum Act, for managing the collections and associated research and dissemination. The Natural History Museum Denmark has exhibitions at its main address on Øster Voldgade 5-7. In addition, the museum holds lectures, guided tours and events that focus on the collections, the Botanical Garden and the researchers' current research. The museum has a school service that offers teaching to students. As planned, the museum will open a new building i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features Peer review, peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan (publisher), Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the j ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genome Databases
A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The first genome to be sequenced was that of the virus φX174 in 1977; the first genome sequence of a prokaryote (''Haemophilus influenzae'') was published in 1995; the yeast (''Saccharomyces cerevisiae'') genome was the first eukaryotic genome to be sequenced in 1996. The Human Genome Project was started in October 1990, and the first draft sequence ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Research Institutes In Denmark
Research is creative and systematic work undertaken to increase the stock of knowledge. It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion of past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, eco ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Paleogenomics
Paleogenomics is a field of science based on the reconstruction and analysis of genomic information in extinct species. Improved methods for the extraction of ancient DNA (aDNA) from museum artifacts, ice cores, archeological or paleontological sites, and next-generation sequencing technologies have spurred this field. It is now possible to detect genetic drift, ancient population migration and interrelationships, the evolutionary history of extinct plant, animal and ''Homo'' species, and identification of phenotypic features across geographic regions. Scientists can also use paleogenomics to compare ancient ancestors against modern-day humans. The rising importance of paleogenomics is evident from the fact that the 2022 Nobel Prize in physiology or medicine was awarded to a Swedish geneticist Svante Pääbo 955- who worked on paleogenomics. Background Initially, aDNA sequencing involved cloning small fragments into bacteria, which proceeded with low efficiency due to the oxidati ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Full Genome Sequence
Whole genome sequencing (WGS), also known as full genome sequencing or just genome sequencing, is the process of determining the entirety of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of gene sequencing at SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. Whole genome sequencing should not be confused with DNA profiling, which only determines the likelihood that genetic ma ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pleistocene/Holocene Megafauna Extinctions
The Late Pleistocene to the beginning of the Holocene saw the extinction of the majority of the world's megafauna, typically defined as animal species having body masses over , which resulted in a collapse in faunal density and diversity across the globe. The extinctions during the Late Pleistocene are differentiated from previous extinctions by their extreme size bias towards large animals (with small animals being largely unaffected), and widespread absence of ecological succession to replace these extinct megafaunal species, and the regime shift of previously established faunal relationships and habitats as a consequence. The timing and severity of the extinctions varied by region and are generally thought to have been driven by humans, climatic change, or a combination of both. Human impact on megafauna populations is thought to have been driven by hunting ("overkill"), as well as possibly environmental alteration. The relative importance of human vs climatic factors in th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Human Genome
The human genome is a complete set of nucleic acid sequences for humans, encoded as the DNA within each of the 23 distinct chromosomes in the cell nucleus. A small DNA molecule is found within individual Mitochondrial DNA, mitochondria. These are usually treated separately as the nuclear genome and the Human mitochondrial genetics, mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of non-coding DNA, DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of RNA#Regulatory RNA, regulatory RNAs. It also includes Promoter (biology), promoters and their associated Cis-regulatory element, gene-regulatory elements, DNA playing structural and replicatory roles, such as Scaffold/matrix attachment region, scaffolding regions, telomeres, centromeres, and Origin of replication, origins of repl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Science (journal)
''Science'' is the peer review, peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature (journal), Nature'' cover the full range of List of academ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Holocene
The Holocene () is the current geologic time scale, geological epoch, beginning approximately 11,700 years ago. It follows the Last Glacial Period, which concluded with the Holocene glacial retreat. The Holocene and the preceding Pleistocene together form the Quaternary period. The Holocene is an interglacial period within the ongoing Ice age, glacial cycles of the Quaternary, and is equivalent to Marine isotope stages, Marine Isotope Stage 1. The Holocene correlates with the last maximum axial tilt towards the Sun of the Earth#Axial tilt and seasons, Earth's obliquity. The Holocene corresponds with the rapid proliferation, growth, and impacts of the human species worldwide, including Recorded history, all of its written history, technological revolutions, development of major civilizations, and overall significant transition towards urban culture, urban living in the present. The human impact on modern-era Earth and its ecosystems may be considered of global significance for th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Copenhagen
The University of Copenhagen (, KU) is a public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia, after Uppsala University. The University of Copenhagen consists of six different Faculty (division), faculties, with teaching taking place in its four distinct campuses, all situated in Copenhagen. The university operates 36 different departments and 122 separate research centres in Copenhagen, as well as a number of museums and botanical gardens in and outside the Danish capital. The University of Copenhagen also owns and operates multiple research stations around Denmark, with two additional ones located in Greenland. Additionally, University of Copenhagen Faculty of Health and Medical Sciences, The Faculty of Health and Medical Sciences and the public hospitals of the Capital Region of Denmark, Capital and Region Zealand, Zealand Region of Denmark constitute the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Late Pleistocene
The Late Pleistocene is an unofficial Age (geology), age in the international geologic timescale in chronostratigraphy, also known as the Upper Pleistocene from a Stratigraphy, stratigraphic perspective. It is intended to be the fourth division of the Pleistocene Epoch within the ongoing Quaternary Period. It is currently defined as the time between 129,000 and c. 11,700 years ago. The late Pleistocene equates to the proposed Tarantian Age of the geologic time scale, preceded by the officially ratified Chibanian (commonly known as the Middle Pleistocene). The beginning of the Late Pleistocene is the transition between the end of the Penultimate Glacial Period and the beginning of the Last Interglacial around 130,000 years ago (corresponding with the beginning of Marine Isotope Stage 5). The Late Pleistocene ends with the termination of the Younger Dryas, some 10th millennium BC, 11,700 years ago when the Holocene Epoch began. The term Upper Pleistocene is currently in use as a p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |