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Centre For Evidence Based Medicine
The Centre for Evidence-Based Medicine (CEBM), based in the Nuffield Department of Primary Care Health Sciences at the University of Oxford, is an academic-led centre dedicated to the practice, teaching, and dissemination of high quality evidence-based medicine to improve healthcare in everyday clinical practice. CEBM was founded by David Sackett in 1995. It was subsequently directed by Brian Haynes and Paul Glasziou. Since 2010 it has been led by Professor Carl Heneghan, a clinical epidemiologist and general practitioner. There are currently over 25 active staff and honorary members of the CEBM. The staff include clinicians, statisticians, epidemiologists, information specialists, quantitative and qualitative researchers. Teaching and degrees CEBM is the academic lead for Oxford University's Graduate School in Evidence-Based Healthcare, together with the university's Department of Continuing Education. The Graduate School includes a MSc in Evidence-Based Health Care and a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oxford
The University of Oxford is a collegiate university, collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the List of oldest universities in continuous operation, second-oldest continuously operating university globally. It expanded rapidly from 1167, when Henry II of England, Henry II prohibited English students from attending the University of Paris. When disputes erupted between students and the Oxford townspeople, some Oxford academics fled northeast to Cambridge, where they established the University of Cambridge in 1209. The two English Ancient university, ancient universities share many common features and are jointly referred to as ''Oxbridge''. The University of Oxford comprises 43 constituent colleges, consisting of 36 Colleges of the University of Oxford, semi-autonomous colleges, four permanent private halls and three societies (colleges that are depar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tamiflu
Oseltamivir, sold under the brand name Tamiflu among others, is an antiviral medication used to treat and prevent influenza A and influenza B, viruses that cause the flu. Many medical organizations recommend it in people who have complications or are at high risk of complications within 48 hours of first symptoms of infection. They recommend it to prevent infection in those at high risk, but not the general population. The Centers for Disease Control and Prevention (CDC) recommends that clinicians use their discretion to treat those at lower risk who present within 48 hours of first symptoms of infection. It is taken by mouth, either as a pill or liquid. Recommendations regarding oseltamivir are controversial as are criticisms of the recommendations. A 2014 Cochrane Review concluded that oseltamivir does not reduce hospitalizations, and that there is no evidence of reduction in complications of influenza. Two meta-analyses have concluded that benefits in those who are other ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy, treatment and antibiotic prophylaxis, prevention of such infections. They may either bactericide, kill or bacteriostatic agent, inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the ones which cause the common cold or influenza. Drugs which inhibit growth of viruses are termed antiviral drugs or antivirals. Antibiotics are also not effective against fungi. Drugs which inhibit growth of fungi are called antifungal drugs. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek language, Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimicrobial Resistance
Antimicrobial resistance (AMR or AR) occurs when microbes evolve mechanisms that protect them from antimicrobials, which are drugs used to treat infections. This resistance affects all classes of microbes, including bacteria (antibiotic resistance), viruses (antiviral resistance), Parasitic disease, parasites (antiparasitic resistance), and fungi (antifungal resistance). Together, these adaptations fall under the AMR umbrella, posing significant challenges to healthcare worldwide. Misuse and improper management of antimicrobials are primary drivers of this resistance, though it can also occur naturally through genetic mutations and the spread of resistant genes. Antibiotic resistance, a significant AMR subset, enables bacteria to survive antibiotic treatment, complicating infection management and treatment options. Resistance arises through spontaneous mutation, horizontal gene transfer, and increased selective pressure from Antibiotic misuse, antibiotic overuse, both in medicin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Department Of Health (United Kingdom)
The Department of Health and Social Care (DHSC) is a Departments of the Government of the United Kingdom, ministerial department of the Government of the United Kingdom. It is responsible for government policy on health and adult social care matters in England, along with a few elements of the same matters which are not otherwise devolved to the Scottish Government, Welsh Government or Northern Ireland Executive. It oversees the English National Health Service (NHS). The department is led by the Secretary of State for Health and Social Care with three ministers of state and three parliamentary under-secretaries of state. The department develops policies and guidelines to improve the quality of care and to meet patient expectations. It carries out some of its work through Quango, arms-length bodies (ALBs), including executive non-departmental public bodies such as NHS England and the NHS Digital, and executive agencies such as the UK Health Security Agency and the Medicines and He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AllTrials
AllTrials (sometimes called All Trials or AllTrials.net) is a project advocating that clinical research adopt the principles of open research. The project summarizes itself as "All trials registered, all results reported": that is, all clinical trials should be listed in a clinical trials registry, and their results should always be shared as open data. At the center of the organisation is a petition signed by over 85,000 individuals and 599 organisations (as of August 2015): Ben Goldacre, author of '' Bad Science'' and '' Bad Pharma'', is a founder of the campaign and its most public spokesperson. In 2016, he participated in the launch of the OpenTrials database. AllTrials is an international initiative of Bad Science, '' BMJ'', Centre for Evidence-based Medicine, Cochrane Collaboration, James Lind Initiative, '' PLOS'' and Sense about Science and is being led in the US by Sense about Science USA, Dartmouth's Geisel School of Medicine and the Dartmouth Institute for He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-communicable Disease
A non-communicable disease (NCD) is a disease that is not transmission (medicine), transmissible directly from one person to another. NCDs include Parkinson's disease, autoimmune diseases, strokes, heart diseases, cancers, Diabetes mellitus, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others. NCDs may be chronic condition, chronic or acute (medicine), acute. Most are non-infection, infectious, although there are some non-communicable infectious diseases, such as parasitic diseases in which the parasite's biological life cycle, life cycle does not include direct host-to-host transmission. The four main NCDs that are the leading causes of death globally are cardiovascular disease, cancer, Respiratory disease, chronic respiratory diseases, and diabetes. NCDs account for seven out of the ten leading causes of death worldwide. Figures given for 2019 are 41 million deaths due to NCDs worldwide. Of these 17.9 million were due to car ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization Collaborating Centre
World Health Organization collaborating centres are institutions that work with the World Health Organization (WHO) in disciplines such as occupational health, food safety, and communicable disease prevention. There are over 700 such centres across 80 countries. Collaborating centres may be research institutes, parts of universities, or academies. The participating institutions partner with WHO to perform research, provide training, or offer other services in furthering the WHO health agenda. These partners are designated by the WHO director-general as a part of a collaborative network. By using networks of established organizations, WHO is able to strengthen the scientific validity of its work and lower the costs of research. Centres worldwide The World Health Organization has established networks related to a variety of health topics. For example, WHO has put in place centres focused on organ transplants, hearing loss prevention, hepatitis, leprosy, medical ethics, and maternal he ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Cochrane Database Of Systematic Reviews
The Cochrane Library (named after Archie Cochrane) is a collection of databases in medicine and other healthcare specialties provided by Cochrane and other organizations. At its core is the collection of Cochrane Reviews, a database of systematic reviews and meta-analyses that summarize and interpret the results of medical research. The Cochrane Library aims to make the results of well-conducted clinical trials readily available and is a key resource in evidence-based medicine. Access and use The Cochrane Library is a subscription-based database, published initially by Update Software and now published by John Wiley & Sons, Ltd. as part of Wiley Online Library. In many countries, including parts of Canada, the United Kingdom, Ireland, the Scandinavian countries, New Zealand, Australia, India, South Africa, and Poland, it has been made available free to all residents by "national provision" (typically a government or Department of Health pays for the license). There are also arra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thromboembolic
Thrombosis () is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss. Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus. Thrombosis can cause serious conditions such as stroke and heart attack. Thrombosis may occur in veins ( venous thrombosis) or in arteries ( arterial thrombosis). Venous thrombosis (sometimes called DVT, deep vein thrombosis) leads to a blood clot in the affected part of the body, while arterial thrombosis (and, rarely, severe venous thrombosis) affects the blood supply and leads to damage of the tissue supplied by that artery (ischemia and necrosis). A piece of either an arterial or a venous th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The British Journal Of General Practice
The ''British Journal of General Practice'' is a monthly peer-reviewed medical journal for general practitioners and primary care researchers. History The journal was established in 1953 as the ''College of General Practitioners' Research Newsletter''. It was renamed ''Journal of the College of General Practitioners'' in 1960 (from 1967 ''Journal of the Royal College of General Practitioners''), before obtaining its current name in 1990. Since 2013, the journal's digital content is hosted by HighWire Press. Research articles are published as open access. The journal publishes editorials on clinical and policy topics, debate and analysis, clinical guidance, and a section called "Life & Times" which contains reviews of art, books, and film as well as viewpoints, polemic, and entertainment. In the course of its history, the journal has had nine editors: Roger Jones was the editor-in-chief until April 2020 and the current editor is Euan Lawson. The editorial office and the journal t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Warfarin
Warfarin, sold under the brand name Coumadin among others. It is used as an anticoagulant, anticoagulant medication. It is commonly used to prevent deep vein thrombosis and pulmonary embolism, and to protect against stroke in people who have atrial fibrillation, valvular heart disease, or artificial heart valves. Warfarin may sometimes be prescribed following a ST-segment elevation myocardial infarction and orthopedic surgery. It is usually taken by mouth, but may also be administered intravenously. The common side effect, a natural consequence of reduced clotting, is bleeding. Less common side effects may include areas of tissue necrosis, tissue damage, and purple toes syndrome. Use is not recommended during pregnancy. The effects of warfarin are typically monitored by checking prothrombin time (INR) every one to four weeks. Many other medications and Diet (nutrition), dietary factors can interact with warfarin, either increasing or decreasing its effectiveness. The effec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
