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Cancer Cluster
A cancer cluster is a disease cluster in which a high number of cancer cases occurs in a group of people in a particular geographic area over a limited period of time.Cancer Cluster FAQ Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Environmental Hazards and Health Effects. Historical examples of work-related cancer clusters are well documented in the medical literature. Notable examples include: scrotal cancer among chimney sweeps in 18th century London; osteosarcoma among [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Cancer Clusters
A cancer cluster is a disease cluster in which a high number of cancer cases occurs in a group of people in a particular geographic area over a limited period of time.Cancer Cluster FAQ Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Environmental Hazards and Health Effects. Historical examples of work-related cancer clusters are well documented in the medical literature. Notable examples include: scrotal cancer among chimney sweeps in 18th century ; osteosarcoma among [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Disease Cluster
A disease cluster is an unusually large aggregation of a relatively uncommon medical condition or event within a particular geographical location or period. Recognition of a cluster depends on its size being seen as greater than would be expected by the play of chance. Identification of a suspected disease cluster may initially depend on anecdotal evidence. Epidemiologists and biostatisticians need to assess whether the suspected cluster corresponds to an actual increase of disease in the area. Typically, when clusters are recognized, they are reported to public health departments in the local area. If clusters are of sufficient size and importance, they may be re-evaluated as outbreaks. John Snow's pioneering investigation of the 1854 cholera outbreak in Soho, London, is seen as a classic example of the study of such a cluster. References External links Disease Clusters: An Overview introduction to a course held by the Agency for Toxic Substances and Disease Registry {{di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Diethylstilbestrol
Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is presently rarely used. In the past, it was widely used for a variety of indications, including pregnancy support for those with a history of recurrent miscarriage, hormone therapy for menopausal symptoms and estrogen deficiency, treatment of prostate cancer and breast cancer, and other uses. By 2007, it was only used in the treatment of prostate cancer and breast cancer. In 2011, Hoover and colleagues reported on adverse health outcomes linked to DES including infertility, miscarriage, ectopic pregnancy, preeclampsia, preterm birth, stillbirth, infant death, menopause prior to age 45, breast cancer, cervical cancer, and vaginal cancer. While most commonly taken by mouth, DES was available for use by other routes as well, for instance, vaginal, topical, and by injection. DES is an estrogen, or an agonist of the estrogen receptors, the biological target of es ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Toxicology
Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, duration of exposure (whether it is acute or chronic), route of exposure, species, age, sex, and environment. Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology is currently contributing to the field of cancer research, since some toxins can be used as drugs for killing tumor cells. One prime example of this is ribosome-inactivating proteins, tested in the treatment of leukemia. The word ''toxicology'' () is a neoclas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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A Story Of Science And Salvation
A, or a, is the first letter and the first vowel letter of the Latin alphabet, used in the modern English alphabet, and others worldwide. Its name in English is '' a'' (pronounced ), plural ''aes''. It is similar in shape to the Ancient Greek letter alpha, from which it derives. The uppercase version consists of the two slanting sides of a triangle, crossed in the middle by a horizontal bar. The lowercase version is often written in one of two forms: the double-storey and single-storey . The latter is commonly used in handwriting and fonts based on it, especially fonts intended to be read by children, and is also found in italic type. In English, '' a'' is the indefinite article, with the alternative form ''an''. Name In English, the name of the letter is the ''long A'' sound, pronounced . Its name in most other languages matches the letter's pronunciation in open syllables. History The earliest known ancestor of A is ''aleph''—the first letter of the Phoenician ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Risk Assessment
Broadly speaking, a risk assessment is the combined effort of: # identifying and analyzing potential (future) events that may negatively impact individuals, assets, and/or the environment (i.e. hazard analysis); and # making judgments "on the tolerability of the risk on the basis of a risk analysis" while considering influencing factors (i.e. risk evaluation). Put in simpler terms, a risk assessment determines possible mishaps, their likelihood and consequences, and the tolerances for such events. The results of this process may be expressed in a quantitative or qualitative fashion. Risk assessment is an inherent part of a broader risk management strategy to help reduce any potential risk-related consequences. Need Individual risk assessment Risk assessment are done in individual cases, including patient and physician interactions. Individual judgements or assessments of risk may be affected by psychological, ideological, religious or otherwise subjective factors, which imp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Incidence (epidemiology)
In epidemiology, incidence is a measure of the probability of occurrence of a given medical condition in a population within a specified period of time. Although sometimes loosely expressed simply as the number of new cases during some time period, it is better expressed as a proportion or a rate with a denominator. Incidence proportion Incidence proportion (IP), also known as cumulative incidence, is defined as the probability that a particular event, such as occurrence of a particular disease, has occurred before a given time. It is calculated dividing the number of new cases during a given period by the number of subjects at risk in the population initially at risk at the beginning of the study. Where the period of time considered is an entire lifetime, the incidence proportion is called lifetime risk. For example, if a population initially contains 1,000 persons and 28 develop a condition since the disease first occurred until two years later, the cumulative incidence p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Fooled By Randomness
''Fooled by Randomness: The Hidden Role of Chance in Life and in the Markets'' is a book by Nassim Nicholas Taleb that deals with the fallibility of human knowledge. It was first published in 2001. Updated editions were released a few years later. The book is the first part of Taleb's multi-volume philosophical essay on uncertainty, titled the ''Incerto'', which also includes '' The Black Swan'' (2007–2010), '' The Bed of Procrustes'' (2010–2016), '' Antifragile'' (2012), and '' Skin in the Game'' (2018). Thesis Taleb sets forth the idea that modern humans are often unaware of the existence of randomness. They tend to explain random outcomes as non-random. Human beings: # overestimate causality, e.g., they see elephants in the clouds instead of understanding that they are in fact randomly shaped clouds that appear to our eyes as elephants (or something else); # tend to view the world as more explainable than it really is. So they look for explanations even when there are non ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Environmental Racism
Environmental racism or ecological apartheid is a form of institutional racism leading to landfills, incinerators, and hazardous waste disposal being disproportionally placed in communities of colour. Internationally, it is also associated with extractivism, which places the environmental burdens of mining, oil extraction, and industrial agriculture upon Indigenous peoples and poorer nations largely inhabited by people of colour. Response to environmental racism has contributed to the environmental justice movement, which developed in the United States and abroad throughout the 1970s and 1980s. Environmental racism may disadvantage minority groups or numerical majorities, as in South Africa where apartheid had debilitating environmental impacts on Black people. Internationally trade in global waste disadvantages global majorities in poorer countries largely inhabited by people of colour. It also applies to the particular vulnerability of indigenous groups to environmental pol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Cancer Epidemiology
The epidemiology of cancer is the study of the factors affecting cancer, as a way to infer possible trends and causes. The study of cancer epidemiology uses epidemiological methods to find the cause of cancer and to identify and develop improved treatments. This area of study must contend with problems of lead time bias and length time bias. Lead time bias is the concept that early diagnosis may artificially inflate the survival statistics of a cancer, without really improving the natural history of the disease. Length bias is the concept that slower growing, more indolent tumors are more likely to be diagnosed by screening tests, but improvements in diagnosing more cases of indolent cancer may not translate into better patient outcomes after the implementation of screening programs. A related concern is overdiagnosis, the tendency of screening tests to diagnose diseases that may not actually impact the patient's longevity. This problem especially applies to prostate cancer a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Cancer Alley
Cancer Alley (french: Allée du Cancer) is the regional nickname given to an stretch of land along the Mississippi River between Baton Rouge and New Orleans, in the River Parishes of Louisiana, which contains over 150 petrochemical plants and refineries. This area accounts for 25% of the petrochemical production in the United States. The region is considered a sacrifice zone. In Cancer Alley, forty-six individuals per one million are at risk of developing cancer, compared with the national average of roughly thirty individuals per one million. The abnormally high cancer risk and concentration of petrochemical operations inspired the "Cancer Alley" moniker. Additionally, researchers have found that racial disparity in cancer risk from air pollution worsen as minority concentration increases across the region. Individuals in black-dominant areas are 16% more at risk than those in white-dominant areas, and people in low-income tracts also bear a cumulative risk 12% more than tho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |