Anelloviridae
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Anelloviridae
''Anelloviridae'' is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3. The name is derived from Italian ''anello'' 'ring', referring to the circular genome of anelloviruses. It is the sole representative of its own phylum, ''Commensaviricota'' (from its "commensal" lifestyle in the human virome + -viricota). Genome The genome is not segmented and contains a single molecule of circular, negative-sense, single-stranded DNA. The complete genome is 3000–4000 nucleotides long. They also contain a non-coding region with one to two 80–110 nt sequences that contain high GC content, forming a secondary structure of stems and loops. The genome has ORFs and a high degree of genetic diversity. Although the mechanism of replication has not been studied heavily, anelloviridae appears to use the rolling circle mechanism where first ssDNA is converted ...
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Alphatorquevirus
''Alphatorquevirus'' is a genus of viruses in the family ''Anelloviridae'', in group II in the Baltimore classification. It encompasses numerous species of the virus known as TTV (transfusion-transmitted virus), torque teno virus, SENV (senior virus), SANBAN, and various other names. The genus contains 26 species. Taxonomy The genus contains the following species: * ''Alphatorquevirus cerco1'' * ''Alphatorquevirus cerco2'' * ''Alphatorquevirus cerco3'' * ''Alphatorquevirus cerco5'' * ''Alphatorquevirus cerco6'' * ''Alphatorquevirus cerco7'' * ''Alphatorquevirus homin1'' * ''Alphatorquevirus homin2'' * ''Alphatorquevirus homin3'' * ''Alphatorquevirus homin4'' * ''Alphatorquevirus homin5'' * ''Alphatorquevirus homin6'' * ''Alphatorquevirus homin7'' * ''Alphatorquevirus homin9'' * ''Alphatorquevirus homin10'' * ''Alphatorquevirus homin13'' * ''Alphatorquevirus homin14'' * ''Alphatorquevirus homin15'' * ''Alphatorquevirus homin17'' * ''Alphatorquevirus homin18'' * ''Alphatorquevirus ...
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Epsilontorquevirus
''Epsilontorquevirus'' is a genus in the family ''Anelloviridae ''Anelloviridae'' is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3. The name is derived from Italian ''ane ...'', in group II in the Baltimore classification. It has a single species, Torque teno tamarin virus (''Epsilontorquevirus calli1''). References External links ICTV Virus Taxonomy 2009UniProt Taxonomy Anelloviridae Virus genera {{Virus-stub ...
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Gammatorquevirus
''Gammatorquevirus'' is a genus of viruses in the family ''Anelloviridae'', in group DNA virus#Group II: ssDNA viruses, II in the Baltimore classification. It contains 15 species. The fifteen species are all commonly called "torque teno midi virus" (TTMDV), number 1–15. Taxonomy The genus contains the following species: * ''Gammatorquevirus homidi1'' * ''Gammatorquevirus homidi2'' * ''Gammatorquevirus homidi3'' * ''Gammatorquevirus homidi4'' * ''Gammatorquevirus homidi5'' * ''Gammatorquevirus homidi6'' * ''Gammatorquevirus homidi7'' * ''Gammatorquevirus homidi8'' * ''Gammatorquevirus homidi9'' * ''Gammatorquevirus homidi10'' * ''Gammatorquevirus homidi11'' * ''Gammatorquevirus homidi12'' * ''Gammatorquevirus homidi13'' * ''Gammatorquevirus homidi14'' * ''Gammatorquevirus homidi15'' Discovery TTMDV, which stands for transfusion transmitted midi virus or torque teno midi virus was first isolated in 2005 from patients with an acute viral infection syndrome. Because of the circ ...
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Gyrovirus
''Gyrovirus'' is a genus of viruses, in the family ''Anelloviridae''. Until 2011, chicken anemia virus was the only gyrovirus identified, but since then gyroviruses have also been identified in humans. Diseases associated with this genus include: chicken infectious anemia, which is associated with depletion of cortical thymocytes and erythroblastoid cells. Taxonomy The genus contains the following species: * ''Gyrovirus anas1'' * ''Gyrovirus anas2'' * ''Gyrovirus chauna1'' * ''Gyrovirus chickenanemia'' ( Chicken anemia virus) * ''Gyrovirus fulgla1'' * ''Gyrovirus galga1'' * ''Gyrovirus galga2'' * ''Gyrovirus homsa1'' * ''Gyrovirus homsa2'' * ''Gyrovirus homsa3'' * ''Gyrovirus homsa4'' * ''Gyrovirus hydho1'' * ''Gyrovirus myferr1'' * ''Gyrovirus phaco1'' Structure Gyroviruses have an average size of 19 to 27 nanometers. They are nonenveloped and have an icosahedral capsid with T=1 symmetry. The unique, single protein, trumpet-shaped capsomeres of ''Gyrovirus'' are arranged ...
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Deltatorquevirus
''Deltatorquevirus'' is a genus of viruses in the family ''Anelloviridae ''Anelloviridae'' is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3. The name is derived from Italian ''ane ...'', in group II in the Baltimore classification. It has a single species, Torque teno tupaia virus (''Deltatorquevirus tupai1''). References External links ICTV Virus Taxonomy 2009UniProt Taxonomy* Anelloviridae Virus genera {{Virus-stub ...
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Betatorquevirus
''Betatorquevirus'' is a genus of viruses in the family ''Anelloviridae ''Anelloviridae'' is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3. The name is derived from Italian ''ane ...'', in group II in the Baltimore classification. The genus ''Betatorquevirus'' includes all "torque teno mini viruses" (TTMV), numbered from 1 to 38. Taxonomy The genus contains the following species: * ''Betatorquevirus homini1'' * ''Betatorquevirus homini2'' * ''Betatorquevirus homini3'' * ''Betatorquevirus homini4'' * ''Betatorquevirus homini5'' * ''Betatorquevirus homini6'' * ''Betatorquevirus homini7'' * ''Betatorquevirus homini8'' * ''Betatorquevirus homini9'' * ''Betatorquevirus homini10'' * ''Betatorquevirus homini11'' * ''Betatorquevirus homini12'' * ''Betatorquevirus homini13'' * ''Betatorquevirus homini14'' * ''Betatorquevirus homini15'' * ''Betato ...
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Iotatorquevirus
''Iotatorquevirus'' is a genus of viruses in the family ''Anelloviridae'', in group II in the Baltimore classification. The genus has two species: ''Iotatorquevirus suida1a'' and ''Iotatorquevirus ursid17''. Virology The virions are small and non-enveloped. The viruses are usually acquired soon after birth and may invade virtually any tissue in the body. They are widespread in the pig population. Genome Iotatorqueviruses have a circular, single-stranded DNA genome. The genome is negative-sense. Clinical Postweaning multisystemic wasting syndrome Porcine circoviral disease (PCVD), also known as porcine circovirus associated disease (PCVAD), is a disease seen in domestic pigs. This disease causes illness in Piglet (animal), piglets, with clinical signs including progressive loss of body co ... has been causally associated with porcine circovirus type 2. The Iotatorquevirus have also been linked with this syndrome but a causative role—if one exists—has yet to be establish ...
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Kappatorquevirus
''Kappatorquevirus'' is a genus of viruses, in the family ''Anelloviridae ''Anelloviridae'' is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3. The name is derived from Italian ''ane ...''. Pigs serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: possibly post-weaning multisystemic wasting syndrome (PMWS). Structure Viruses in ''Kappatorquevirus'' are non-enveloped, with icosahedral geometries, and T=1 symmetry. The diameter is around 19-27 nm. Genomes are circular, around 2.7kb in length. The genome codes for 4 proteins, and has 3 open reading frames. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by penetration into the host cell. Replication follows the ssDNA rolling circle model. DNA-templated transcription, with some alternative splicing mechani ...
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Lambdatorquevirus
''Lambdatorquevirus'' is a genus of viruses, in the family ''Anelloviridae ''Anelloviridae'' is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3. The name is derived from Italian ''ane ...''. Sea lions serve as natural hosts. There are five species in this genus. Taxonomy The genus contains the following species: * ''Lambdatorquevirus phoci1'' * ''Lambdatorquevirus phoci2'' * ''Lambdatorquevirus phoci3'' * ''Lambdatorquevirus phoci5'' * ''Lambdatorquevirus phoci6'' Structure Viruses in ''Lambdatorquevirus'' are non-enveloped, with icosahedral geometries, and T=1 symmetry. The diameter is around 19-27 nm. Genomes are circular, around 2.1kb in length. The genome has 2 open reading frames. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by penetration into the host cell. Replication follows the ssDNA rolli ...
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Etatorquevirus
''Etatorquevirus'' is a genus of viruses in the family ''Anelloviridae ''Anelloviridae'' is a family of viruses. They are classified as vertebrate viruses and have a non-enveloped capsid, which is round with isometric, icosahedral symmetry and has a triangulation number of 3. The name is derived from Italian ''ane ...'', in group II in the Baltimore classification. It includes 18 species. Taxonomy The genus contains the following species: * ''Etatorquevirus felid1'' * ''Etatorquevirus felid2'' * ''Etatorquevirus felid3'' * ''Etatorquevirus felid4'' * ''Etatorquevirus felid5'' * ''Etatorquevirus felid17'' * ''Etatorquevirus felid18'' * ''Etatorquevirus felid19'' * ''Etatorquevirus felid20'' * ''Etatorquevirus felid21'' * ''Etatorquevirus felid22'' * ''Etatorquevirus felid24'' * ''Etatorquevirus felid25'' * ''Etatorquevirus felid26'' * ''Etatorquevirus felid27'' * ''Etatorquevirus felid28'' * ''Etatorquevirus felid35'' * ''Etatorquevirus viver3'' References External l ...
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Human Virome
The human virome is the total collection of viruses in and on the human body. Viruses in the human body may infect both human cells and other microbes such as bacteria (as with bacteriophages). Some viruses cause disease, while others may be asymptomatic. Certain viruses are also integrated into the human genome as proviruses or endogenous viral elements. Viruses evolve rapidly and hence the human virome changes constantly. Every human being has a unique virome with a unique balance of species. Lifestyle, age, geographic location, and even the season of the year can affect an individual's exposure to viruses, and one's susceptibility to any disease that might be caused by those viruses is also affected by pre-existing immunity and both viral and human genetics. The human virome is far from being completely explored and new viruses are discovered frequently. Unlike the roughly 40 trillion bacteria in a typical human microbiome, an estimate of the number of viral particles in a h ...
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