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Benign Neonatal Seizures
Benign neonatal seizures include two disorders: self-limited (benign) neonatal seizures and self-limited (benign) familial neonatal seizures. Self-limited neonatal seizures Self-limited neonatal seizures are a diagnosis of exclusion. 90% occur within the first 4-6 days of life, thus coining the term "fifth day fits". Seizures typically resolve by six weeks of life. Some suspected etiologies include rotavirus infections, de-novo (first time) mutations in genes encoding for voltage-gated potassium channels (KCNQ2, KCNQ3), and acute zinc deficiency in cerebrospinal fluid. Presentation Most frequently the seizure is focal tonic and involves the head, face, and limbs. Focal tonic seizures are defined as sustained flexion or extension of muscle groups. Focal clonic seizures can also occur, which are defined as rhythmic movements of muscle groups. Seizures can alternate sides and progress to bilateral tonic seizures. There may also be associated apnea in a third of patients. The dura ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seizure Types
In the field of neurology, seizure types refer to clinically and electrographically defined categories of seizures, based on observable features, underlying mechanisms, and diagnostic findings. A seizure is a paroxysmal episode of altered behavior, sensation, awareness, or autonomic function resulting from abnormal, excessive, or synchronous neuronal activity in the brain. Seizure classification plays a central role in the diagnosis and treatment of epilepsy and related disorders. It guides therapeutic decisions, informs prognosis, and supports communication among clinicians, researchers, and patients. The International League Against Epilepsy (ILAE) is the primary body responsible for defining seizure classifications. Its frameworks have evolved to reflect advances in neuroimaging, electrophysiology, and clinical semiology. The most recent system, published in 2025, introduces refined seizure categories aimed at improving diagnostic accuracy and clinical utility. Classification s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |