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Basal Nucleus Of Meynert
In the human brain, the nucleus basalis, also known as the nucleus basalis of Meynert or nucleus basalis magnocellularis, is a group of neurons located mainly in the substantia innominata of the basal forebrain. Most neurons of the nucleus basalis are rich in the neurotransmitter acetylcholine, and they have widespread projections to the neocortex and other brain structures. Structure The nucleus basalis in humans is a somewhat diffuse collection of large cholinergic neurons in the basal forebrain. The main body of the nucleus basalis lies inferior to the anterior commissure and the globus pallidus, and lateral to the anterior hypothalamus in an area known as the substantia innominata. Rostrally, the nucleus basalis is continuous with the cholinergic neurons of the nucleus of the diagonal band of Broca. The nucleus basalis is thought to consist of several subdivisions based on the location of the cells and their projections to other brain regions. Occasional neurons belonging t ...
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Coronal Plane
The dorsal plane (also known as the coronal plane or frontal plane, especially in human anatomy) is an anatomical plane that divides the body into Anatomical terms of location#Dorsal and ventral, dorsal and ventral sections. It is perpendicular to the sagittal plane, sagittal and transverse plane, transverse planes. Human anatomy The coronal plane is an example of a Anatomical terms of location#General usage, longitudinal plane. For a human, the mid-coronal plane would transect a standing body into two halves (front and back, or anterior and posterior) in an imaginary line that cuts through both shoulders. The sternal plane (''planum sternale'') is a coronal plane which transects the front of the Human sternum, sternum. Etymology The term is derived from Latin ''corona'' ('garland, crown'), from Ancient Greek κορώνη (''korōnē'', 'garland, wreath'). The coronal plane is so called because it lies in the same direction as the coronal suture. Additional images File:Coronal ...
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Nucleus Of The Diagonal Band
The diagonal band of Broca interconnects the amygdala and the septal area. It is one of the olfactory structures. It is situated upon the inferior aspect of the brain. It forms the medial margin of the anterior perforated substance. It was described by the French neuroanatomist Paul Broca. Structure It consists of fibers that are said to arise in the parolfactory area, the gyrus subcallosus and the anterior perforated substance, and course backward in the longitudinal striae to the dentate gyrus and the hippocampal region. This is a cholinergic bundle of nerve fibers posterior to the anterior perforated substance. It interconnects the subcallosal gyrus in the septal area with the hippocampus and lateral olfactory area. Nuclei Two structures are often described in this brain regions, namely the nuclei of the vertical and horizontal limbs of the diagonal band of Broca (nvlDBB and nhlDBB, respectively). nvlDBB projects to the hippocampal formation through the fornix and it is t ...
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Albert Von Kölliker
Albert von Kölliker (born Rudolf Albert Kölliker'';'' 6 July 1817 – 2 November 1905) was a Swiss anatomist, physiologist, and histologist. Biography Albert Kölliker was born in Zürich, Switzerland. His early education was carried on in Zürich, and he entered the university there in 1836. After two years, however, he moved to the University of Bonn, and later to that of Berlin, becoming a pupil of noted physiologists Johannes Peter Müller and of Friedrich Gustav Jakob Henle. He graduated in philosophy at Zürich in 1841, and in medicine at Heidelberg in 1842 The first academic post which he held was that of prosector of anatomy under Henle, but his tenure of this office was briefin 1844 he returned to University of Zurich to occupy a chair as professor extraordinary of physiology and comparative anatomy. His stay here was also brief; in 1847 the University of Würzburg, attracted by his rising fame, offered him the post of professor of physiology and of microscopical an ...
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Ansa Peduncularis
Ansa (Latin for "handle") or ANSA may refer to: Organizations * Agenzia Nazionale Stampa Associata, Italian news agency ** Ansa Mediterranean or ANSAmed, section of the above * Applied Neuroscience Society of Australasia * Association of Norwegian Students Abroad Science and technology Anatomy * Ansa cervicalis, a loop of nerves that are part of the cervical plexus * Ansa lenticularis, a part of the brain, making up the superior layer of the substantia innominata of Meynert * Loop of Henle (''ansa nephroni''), a portion of a nephron in the kidney * Ansa of the tympanal organ Astronomy * ''Ansae'', compact nebulosities such as can be found in protoplanetary nebulae * One of the apparent ends of the rings of Saturn Computing * Advanced Networked Systems Architecture, a 1990s, pre-CORBA, distributed systems architecture * ANSA Pre-processor, commercial pre-processing software (Automatic Net-generation for Structural Analysis) Other uses in science and technology * ''Ansa'' ...
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Dementia
Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform activities of daily living, everyday activities. This typically involves problems with memory, thinking, behavior, and motor control. Aside from memory impairment and a thought disorder, disruption in thought patterns, the most common symptoms of dementia include emotional problems, difficulties with language, and decreased motivation. The symptoms may be described as occurring in a continuum (measurement), continuum over several stages. Dementia is a life-limiting condition, having a significant effect on the individual, their caregivers, and their social relationships in general. A diagnosis of dementia requires the observation of a change from a person's usual mental functioning and a greater cognitive decline than might be caused by the normal aging process. Several diseases and injuries to the brain, ...
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ...
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to twelve years. The causes of Alzheimer's disease remain poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. Other risk factors include a history of head injury, clinical depression, and high blood pressure. The progression of the di ...
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Neurodegenerative Diseases
A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. Neuronal damage may also ultimately result in their death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest that thera ...
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Michael Merzenich
Michael Matthias Merzenich ( ; born 1942 in Lebanon, Oregon) is an American neuroscientist and professor emeritus at the University of California, San Francisco. He took the sensory cortex maps developed by his predecessors (Archie Tunturi, Clinton Woolsey, Vernon Mountcastle, Wade Marshall, and Philip Bard) and refined them using dense micro-electrode mapping techniques. Using this, he definitively showed there to be multiple somatotopic maps of the body in the postcentral sulcus, and multiple tonotopic maps of the acoustic inputs in the superior temporal plane. He led the cochlear implant team at UCSF, which transferred its technology to Advanced Bionics, and their version is the Clarion cochlear implant. He collaborated with Bill Jenkins and Gregg Recanzone to demonstrate sensory maps are labile into adulthood in animals performing operant sensory tasks. He collaborated with Paula Tallal, Bill Jenkins, and Steve Miller to form the company Scientific Learning. This was based ...
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Visual Cortex
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 ( V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19). Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field. Introduction The primary visual cortex (V1) is located in and around the calcarine fissure in the occipital lobe. Each h ...
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Lateral Geniculate Body
In neuroanatomy, the lateral geniculate nucleus (LGN; also called the lateral geniculate body or lateral geniculate complex) is a structure in the thalamus and a key component of the mammalian visual pathway. It is a small, ovoid, ventral projection of the thalamus where the thalamus connects with the optic nerve. There are two LGNs, one on the left and another on the right side of the thalamus. In humans, both LGNs have six layers of neurons ( grey matter) alternating with optic fibers (white matter). The LGN receives information directly from the ascending retinal ganglion cells via the optic tract and from the reticular activating system. Neurons of the LGN send their axons through the optic radiation, a direct pathway to the primary visual cortex. In addition, the LGN receives many strong feedback connections from the primary visual cortex. In humans as well as other mammals, the two strongest pathways linking the eye to the brain are those projecting to the dorsal part of ...
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Internal Capsule
The internal capsule is a paired white matter structure, as a two-way nerve tract, tract, carrying afferent nerve fiber, ascending and efferent nerve fiber, descending axon, fibers, to and from the cerebral cortex. The internal capsule is situated in the Anatomical terms of location#Medial and lateral, inferomedial part of each cerebral hemisphere of the brain. It carries information past the subcortical basal ganglia. As it courses it separates the caudate nucleus and the thalamus from the putamen and the globus pallidus. It also separates the caudate nucleus and the putamen in the dorsal striatum, a brain region involved in motor and reward pathways. The internal capsule is V-shaped in transection forming an anterior and posterior limb, with the angle between them called the genu. The corticospinal tract constitutes a large part of the internal capsule, carrying motor information from the primary motor cortex to the lower motor neurons in the spinal cord. Above the basal gangli ...
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